Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Kimberly Batten"'
Autor:
Prasanna Bhat, Vasilisa Aksenova, Matthew Gazzara, Emily A. Rex, Sadaf Aslam, Christina Haddad, Shengyan Gao, Matthew Esparza, Tolga Cagatay, Kimberly Batten, Sara S. El Zahed, Alexei Arnaoutov, Hualin Zhong, Jerry W. Shay, Blanton S. Tolbert, Mary Dasso, Kristen W. Lynch, Adolfo García-Sastre, Beatriz M. A. Fontoura
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Nuclear export of influenza A virus (IAV) mRNAs occurs through the nuclear pore complex (NPC). Using the Auxin-Induced Degron (AID) system to rapidly degrade proteins, we show that among the nucleoporins localized at the nucleoplasmic side o
Externí odkaz:
https://doaj.org/article/ef526c85c77e4e78867cbdc75323343a
Autor:
Yihu Xie, Shengyan Gao, Ke Zhang, Prasanna Bhat, Bradley P. Clarke, Kimberly Batten, Menghan Mei, Matthew Gazzara, Jerry W. Shay, Kristen W. Lynch, Alexia E. Angelos, Pate S. Hill, Austin L. Ivey, Beatriz M.A. Fontoura, Yi Ren
Publikováno v:
Cell Reports, Vol 42, Iss 8, Pp 112988- (2023)
Summary: mRNA in eukaryotic cells is packaged into highly compacted ribonucleoprotein particles (mRNPs) in the nucleus and exported to the cytoplasm for translation. mRNP packaging and export require the evolutionarily conserved transcription-export
Externí odkaz:
https://doaj.org/article/df54e3fcb6014d21ab1a152352313d47
Autor:
Andrew T. Ludlow, Mandy Sze Wong, Jerome D. Robin, Kimberly Batten, Laura Yuan, Tsung-Po Lai, Nicole Dahlson, Lu Zhang, Ilgen Mender, Enzo Tedone, Mohammed E. Sayed, Woodring E. Wright, Jerry W. Shay
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
Splicing of the telomerase transcript, hTERT, can be altered in cancer cells. Here the authors report NOVA1, as a splicing regulator that directly interacts with hTERT pre-mRNA enhancing the number of full-length transcripts and thus telomerase activ
Externí odkaz:
https://doaj.org/article/2cd190c0898f4b9ebf7b01ae510309b7
Autor:
Ilgen Mender, Ryan LaRanger, Krishna Luitel, Michael Peyton, Luc Girard, Tsung-Po Lai, Kimberly Batten, Crystal Cornelius, Maithili P. Dalvi, Michael Ramirez, Wenting Du, Lani F. Wu, Steven J. Altschuler, Rolf Brekken, Elisabeth D. Martinez, John D. Minna, Woodring E. Wright, Jerry W. Shay
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 20, Iss 8, Pp 826-837 (2018)
Standard and targeted cancer therapies for late-stage cancer patients almost universally fail due to tumor heterogeneity/plasticity and intrinsic or acquired drug resistance. We used the telomerase substrate nucleoside precursor, 6-thio-2′-deoxygua
Externí odkaz:
https://doaj.org/article/4cb2a9b75e64451da5d6b5d27e43a411
Autor:
Mahesh S. Padanad, Georgia Konstantinidou, Niranjan Venkateswaran, Margherita Melegari, Smita Rindhe, Matthew Mitsche, Chendong Yang, Kimberly Batten, Kenneth E. Huffman, Jingwen Liu, Ximing Tang, Jaime Rodriguez-Canales, Neda Kalhor, Jerry W. Shay, John D. Minna, Jeffrey McDonald, Ignacio I. Wistuba, Ralph J. DeBerardinis, Pier Paolo Scaglioni
Publikováno v:
Cell Reports, Vol 16, Iss 6, Pp 1614-1628 (2016)
KRAS is one of the most commonly mutated oncogenes in human cancer. Mutant KRAS aberrantly regulates metabolic networks. However, the contribution of cellular metabolism to mutant KRAS tumorigenesis is not completely understood. We report that mutant
Externí odkaz:
https://doaj.org/article/accd4720f8274f44bb862c81497526a0
Autor:
Peter Ly, Ugur Eskiocak, Sang B. Kim, Andres I. Roig, Suzie K. Hight, Dypti R. Lulla, Ying S. Zou, Kimberly Batten, Woodring E. Wright, Jerry W. Shay
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 13, Iss 4, Pp 348-357 (2011)
Chromosomal instability leading to aneuploidy occurs in most sporadic colorectal cancers (CRCs) and is believed to be an early driving force in disease progression. Despite this observation, the cellular advantages conferred by these cytogenetic alte
Externí odkaz:
https://doaj.org/article/c684211bc5fe41269fc99a3ff9c33987
Autor:
Stina M. Singel, Crystal Cornelius, Elma Zaganjor, Kimberly Batten, Venetia R. Sarode, Dennis L. Buckley, Yan Peng, George B. John, Hsiao C. Li, Navid Sadeghi, Woodring E. Wright, Lawrence Lum, Timothy W. Corson, Jerry W. Shay
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 16, Iss 3, Pp 247-256.e2 (2014)
Despite evidence that kinesin family member 14 (KIF14) can serve as a prognostic biomarker in various solid tumors, how it contributes to tumorigenesis remains unclear. We observed that experimental decrease in KIF14 expression increases docetaxel ch
Externí odkaz:
https://doaj.org/article/6c64beef889741d38f469bb388b70ed5
Autor:
Jerry W. Shay, John D. Minna, Boning Gao, Luc Girard, Crystal Cornelius, Aishwarya Vemula, Michael Peyton, Kimberly Batten, Ilgen Mender
Supplementary Table 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c2a0e47cc85a8cdbd234420d2c6e25f
https://doi.org/10.1158/0008-5472.22426140.v1
https://doi.org/10.1158/0008-5472.22426140.v1
Autor:
Jerry W. Shay, Lawrence Lum, Woodring E. Wright, Gail Fasciani, Kimberly Batten, Crystal Cornelius, Stina Mui Singel
PDF File - 35K, Annexin V staining by flow cytometry 24 hours after addition of 1nM docetaxel to MDA-MB-231 cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::145d686c75e6911431b5b30cb743747e
https://doi.org/10.1158/1078-0432.22452152.v1
https://doi.org/10.1158/1078-0432.22452152.v1
Autor:
Jerry W. Shay, Lawrence Lum, Woodring E. Wright, Gail Fasciani, Kimberly Batten, Crystal Cornelius, Stina Mui Singel
PDF File - 86K, List of cell lines (from Neve et al. 2006, see text) with clinical annotations for analysis of KIF14 and TLN1 expression within each clinical subtype of breast cancer.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22b13c7de0d59a6d137bb5c77a10f95b
https://doi.org/10.1158/1078-0432.22452140
https://doi.org/10.1158/1078-0432.22452140