Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Kimberly A. Waller"'
Publikováno v:
International Journal of Molecular Sciences, Vol 18, Iss 6, p 1252 (2017)
Deficiency of PRG4 (lubricin), the boundary lubricant in mammalian joints, contributes to increased joint friction accompanied by superficial and upper intermediate zone chondrocyte caspase-3 activation, as shown in lubricin-null (Prg4−/−) mice.
Externí odkaz:
https://doaj.org/article/3920e110d2a4458dbc7d277ba97be9e8
Autor:
Johannes Konrad, Martha M. Murray, Braden C. Fleming, Benedikt L. Proffen, Naga Padmini Karamchedu, Kaitlyn E. Chin, Ata M. Kiapour, Kimberly A. Waller, Gabriel S. Perrone, Matthew R. Akelman, Jakob T. Sieker
Publikováno v:
Journal of Orthopaedic Research®. 36:2128-2139
To determine the transcriptional profile of synovium during the molecular phase of post-traumatic osteoarthritis, anterior cruciate ligament transections (ACL) were performed in 36 Yucatan minipigs. Equal numbers were randomly assigned to no further
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::48085640e8715da328cf4c0d6d8e4984
https://doi.org/10.1002/jor.23876
https://doi.org/10.1002/jor.23876
Autor:
Ling X. Zhang, Gregory D. Jay, Kimberly A. Waller, Tannin A. Schmidt, Kaitlyn E. Chin, Gary J. Badger, Scott McAllister, Braden C. Fleming, Erin Teeple
Publikováno v:
The American Journal of Sports Medicine. 45:1512-1521
Background: Lubricin, or proteoglycan 4 (PRG4), is a glycoprotein responsible for joint boundary lubrication. PRG4 has been shown previously to be down-regulated after traumatic joint injury such as a meniscal tear. Preliminary evidence suggests that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a8ec48b399499aee50204e1777d3437
https://doi.org/10.1177/0363546516686965
https://doi.org/10.1177/0363546516686965
Autor:
Talia Serrecchia, Kimberly A. Waller, Tomoyoshi Ishikawa, Rafael Muniz, Thomas R. Varricchione
Publikováno v:
International Journal of Human Factors and Ergonomics. 7:144
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d9dfc8e053f9374cc8a59a77c53cd62b
https://doi.org/10.1504/ijhfe.2020.109561
https://doi.org/10.1504/ijhfe.2020.109561
Autor:
David Zurakowski, Steven Hann, Yajun Cui, Ling X. Zhang, Ugur M. Ayturk, Samantha Lessard, Gregory D. Jay, Adele Hill, Kimberly A. Waller, Patrick Smits, Matthew L. Warman, Justin M. Allen
Publikováno v:
Arthritis & Rheumatology. 67:3070-3081
Objective. Congenital deficiency of the principal boundary lubricant in cartilage (i.e., lubricin, encoded by the gene PRG4) increases joint friction and causes progressive joint failure. This study was undertaken to determine whether restoring lubri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68ae91a00db1041135410a92f3efc0d2
https://doi.org/10.1002/art.39276
https://doi.org/10.1002/art.39276
Autor:
Jakob T, Sieker, Benedikt L, Proffen, Kimberly A, Waller, Kaitlyn E, Chin, Naga Padmini, Karamchedu, Matthew R, Akelman, Gabriel S, Perrone, Ata M, Kiapour, Johannes, Konrad, Braden C, Fleming, Martha M, Murray
Publikováno v:
Journal of orthopaedic research : official publication of the Orthopaedic Research Society.
To determine the transcriptional profile of synovium during the molecular phase of post-traumatic osteoarthritis, anterior cruciate ligament transections (ACL) were performed in 36 Yucatan minipigs. Equal numbers were randomly assigned to no further
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6cee7523070b16ae4c14e3df41bdda99
https://pubmed.ncbi.nlm.nih.gov/29460983
https://pubmed.ncbi.nlm.nih.gov/29460983
Autor:
Naga Padmini Karamchedu, Ata M. Kiapour, Matthew R. Akelman, Kimberly A. Waller, Johannes Konrad, Martha M. Murray, Braden C. Fleming, Kaitlyn E. Chin, Gabriel S. Perrone, Jakob T. Sieker, Benedikt L. Proffen
Publikováno v:
Journal of Orthopaedic Research.
To identify the molecular pathophysiology present in early post-traumatic osteoarthritis (PTOA), the transcriptional profile of articular cartilage and its response to surgical PTOA induction were determined. 36 Yucatan minipigs underwent anterior cr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1460016d16552008daedb6380783ed00
https://doi.org/10.1002/jor.23644
https://doi.org/10.1002/jor.23644
Publikováno v:
International Journal of Molecular Sciences; Volume 18; Issue 6; Pages: 1252
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 18, Iss 6, p 1252 (2017)
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 18, Iss 6, p 1252 (2017)
Deficiency of PRG4 (lubricin), the boundary lubricant in mammalian joints, contributes to increased joint friction accompanied by superficial and upper intermediate zone chondrocyte caspase-3 activation, as shown in lubricin-null (Prg4−/−) mice.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca86e3ab04b16579535c8b59c085ec12
Autor:
Kimberly A. Waller, Gregory D. Jay
Publikováno v:
Matrix Biology. 39:17-24
Lubricin is a surface-active mucinous glycoprotein secreted in the synovial joint that plays an important role in cartilage integrity. In healthy joints, lubricin molecules coat the cartilage surface, providing boundary lubrication and preventing cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7fb88bf0ee0192a875daacc414775fb
Autor:
Gregory D. Jay, Khaled A. Elsaid, Kimberly A. Waller, Ling Zhang, Scott C. Anderson, Erin Teeple, Braden C. Fleming, Karen A. Kelly
Publikováno v:
Arthritis & Rheumatism. 64:1162-1171
Objective To investigate whether cartilage degeneration is prevented or minimized in an anterior cruciate ligament (ACL) injury rat model following a single dose-escalated intra-articular injection of lubricin derived from human synoviocytes in cultu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0078d2ba3024d862e458a0d98fcddc46
https://doi.org/10.1002/art.33461
https://doi.org/10.1002/art.33461