Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Kimberly A. Savary"'
Autor:
Robert A. Reamer, David M. Tschaen, Edward J. J. Grabowski, Elizabeth Buck, Ralph P. Volante, Feng Xu, Marjorie S. Waters, Kimberly A. Savary, Matthew M. Bio, Chunhua Yang, Cameron J. Cowden, Zhiguo J. Song, J. Michael Williams
Publikováno v:
The Journal of Organic Chemistry. 69:6257-6266
A practical, efficient synthesis of 1, a hepatitis C virus RNA replication inhibitor, is described. Starting with the inexpensive diacetone glucose, the 12-step synthesis features a novel stereoselective rearrangement to prepare the key crystalline f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d5755c2f58081e7737a80d5c4a0b032
https://doi.org/10.1021/jo0491096
https://doi.org/10.1021/jo0491096
Autor:
David M. Tschaen, Fengrui Lang, Edward G. Corley, Kimberly A. Savary, Feng Xu, Jimmy O. DaSilva, Amude M. Kassim, Anthony O. King, Robert D. Larsen, Peter G. Dormer, Johnnie L. Leazer, Lisa DiMichele
Publikováno v:
Tetrahedron Letters. 45:5429-5432
A general method for the preparation of syn -2,3-disubstituted-2,3-dihydro-1,4-benzoxathiin rings from 2-mercaptoethanols and quinone ketals is presented. This ring system is produced by Michael addition of a 2-mercaptoethanol to a quinone ketal, fol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::58fc8c3353ea66f81f6fac2e01a5c505
https://doi.org/10.1016/j.tetlet.2004.05.047
https://doi.org/10.1016/j.tetlet.2004.05.047
Publikováno v:
Tetrahedron Letters. 44:1283-1286
A novel, high yielding preparation of sulfones from α,α-dibromomethyl aromatics through reaction with a sulfinate salt is reported.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e656202e24482ce17d8f48f1ca9006e7
https://doi.org/10.1016/s0040-4039(02)02769-7
https://doi.org/10.1016/s0040-4039(02)02769-7
Autor:
D. Richard Sidler, Ronald B. Jobson, Fuh-Rong Tsay, Karen M. Conrad, Renato Skerlj, Kimberly A. Savary, G. Marchesini, Peter G. Houghton, Brenda Pipik, Thomas J. Novak, Karel M. J. Brands, Ulf-H. Dolling, Lisa DiMichele, J. Michael Williams
Publikováno v:
The Journal of organic chemistry. 70(19)
[reaction: see text] A practical synthesis for the large-scale production of the new carbapenem antibiotic, [4R,5S,6S]-3-[[(3S,5S)-5-[[(3-Carboxyphenyl)amino]carbonyl]-3-pyrrolidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c86b9c17415a2c1111222370cf7db25
https://pubmed.ncbi.nlm.nih.gov/16149774
https://pubmed.ncbi.nlm.nih.gov/16149774
Publikováno v:
ChemInform. 34
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c5a2afb528cd7c23f6200b6ebab90b3d
https://doi.org/10.1002/chin.200317085
https://doi.org/10.1002/chin.200317085