Výsledky vyhledávání - "Kimberly A. Mamula"

Importance of substantial weight loss for altering gene expression during cardiovascular lifestyle modification

Autor: Marina N. Vernalis, Kimberly A. Mamula, Renata J.M. Engler, Ryan van Laar, Fionnuala A. McDyer, Darrell L. Ellsworth, Nicholas S. Costantino, Heather L. Blackburn, Gera L. Jellema

Publikováno v: Obesity. 23:1312-1319

Objective To examine relationships between weight loss through changes in lifestyle and peripheral blood gene expression profiles. Methods A prospective nonrandomized trial was conducted over 1 year in participants undergoing intensive lifestyle modi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2173832b7d10b4c9a4e291a5bcdaffb8
https://doi.org/10.1002/oby.21079

Zobrazit plný text záznamu

Abundance and distribution of polychlorinated biphenyls (PCBs) in breast tissue

Autor: Craig D. Shriver, Paul J. Kostyniak, Rachel E. Ellsworth, Darrell L. Ellsworth, Brenda Deyarmin, Lai-Har Chi, Kimberly A. Mamula, Nicholas S. Costantino

Publikováno v: Environmental Research. 138:291-297

Many environmental chemicals accumulate in human tissues and may contribute to cancer risk. Polychlorinated biphenyls (PCBs) are associated with adverse health effects, but relationships between PCB exposure and breast cancer are unclear. In this stu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::992d55a9dee78fed00016831504574d9
https://doi.org/10.1016/j.envres.2015.02.025

Zobrazit plný text záznamu

CARDIAC LIFESTYLE INTERVENTIONS DIFFERING IN DIETARY STRINGENCY IMPROVE INSULIN RESISTANCE THROUGH CHANGES IN LIPOPROTEIN PROFILES

Autor: Marina Vernalis, Heather L. Blackburn, Darrell L. Ellsworth, Renata Engler, Kimberly A. Mamula

Publikováno v: Journal of the American College of Cardiology. 65(10)

Metabolic dysfunction characterized by insulin resistance (IR) is an important risk factor for developing type 2 diabetes and coronary artery disease (CAD). The Lipoprotein Insulin Resistance (LP-IR) score, derived from measures of lipoprotein subcla

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15637f65c0fc5baffc51beafaacccf38

Zobrazit plný text záznamu

Intensive cardiovascular risk reduction induces sustainable changes in expression of genes and pathways important to vascular function

Autor: Ryan van Laar, Darrell L. Ellsworth, Gera L. Jellema, Marina N. Vernalis, Jamie D. Weyandt, Mary Jane Haberkorn, Yaqin Chen, Lori A. Sturtz, Amy Burke, Kimberly A. Mamula, Daniel T. Croft, Fionnuala A. McDyer, Heather L. Blackburn

Publikováno v: Circulation. Cardiovascular genetics. 7(2)

Background— Healthy lifestyle changes are thought to mediate cardiovascular disease risk through pathways affecting endothelial function and progression of atherosclerosis; however, the extent, persistence, and clinical significance of molecular ch

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::065d73494c1687738ab9687b9305bf59
https://pubmed.ncbi.nlm.nih.gov/24563419

Zobrazit plný text záznamu

Outcome disparities in African American women with triple negative breast cancer: a comparison of epidemiological and molecular factors between African American and Caucasian women with triple negative breast cancer

Autor: Lori A. Sturtz, Kimberly A. Mamula, Craig D. Shriver, Rachel E. Ellsworth, Jen Melley

Publikováno v: BMC Cancer

Background Although diagnosed less often, breast cancer in African American women (AAW) displays different characteristics compared to breast cancer in Caucasian women (CW), including earlier onset, less favorable clinical outcome, and an aggressive

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25a4991278a9dcd31154caf52cb57d35
https://doi.org/10.1186/1471-2407-14-62

Zobrazit plný text záznamu

Molecular Alterations Associated with Breast Cancer Mortality

Autor: Craig D. Shriver, Laura M. Voeghtly, Rachel E. Ellsworth, J. Leigh Fantacone Campbell, Kimberly A. Mamula

Publikováno v: PLoS ONE
PLoS ONE, Vol 7, Iss 10, p e46814 (2012)

BACKGROUND: Breast cancer is a heterogeneous disease and patients with similar pathologies and treatments may have different clinical outcomes. Identification of molecular alterations associated with disease outcome may improve risk assessment and tr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d28345233b4ecb49bdb19d3223397705
http://europepmc.org/articles/PMC3464216

Zobrazit plný text záznamu

Molecular Heterogeneity in Primary Breast Carcinomas and Axillary Lymph Node Metastases Assessed by Genomic Fingerprinting Analysis

Autor: Craig D. Shriver, Heather L. Blackburn, Alisha Decewicz, Brenda Deyarmin, Rachel E. Ellsworth, Nicholas S. Costantino, Allyson L. Toro, Jeffrey A. Hooke, Darrell L. Ellsworth, Kimberly A. Mamula

Publikováno v: Cancer Growth and Metastasis, Vol 8 (2015)
Cancer Growth and Metastasis
Cancer Growth and Metastasis, Vol 2015, Iss 8, Pp 15-24 (2015)

Molecular heterogeneity within primary breast carcinomas and among axillary lymph node (LN) metastases may impact diagnosis and confound treatment. In this study, we used short tandem repeated sequences to assess genomic heterogeneity and to determin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f4ffb02238ca2b31489cd908a1bf941
https://doi.org/10.4137/cgm.s29490

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání