Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Kimberly A. Holden"'
Autor:
Graham McLennan, Amin Mazloom, Gregory A. Daniels, Daniel S. Grosu, Marcia Eisenberg, Razelle Kurzrock, Kimberly A. Holden, Shumei Kato, Prachi Nakashe, Kerry D. Fitzgerald, Eyad Almasri, Taylor J. Jensen, Christopher K. Ellison, Erin McCarthy, Lisa Kim, Aaron M. Goodman
Publikováno v:
Molecular Cancer Therapeutics. 20:2274-2279
When tissue biopsy is not medically prudent or tissue is insufficient for molecular testing, alternative methods are needed. Because cell-free DNA (cfDNA) has been shown to provide a representative surrogate for tumor tissue, we sought to evaluate it
Autor:
Grant Hogg, Qian Zeng, Heidi M Hoffman, Eric A. Severson, Li Cai, Wenjie Chen, Sabrina Gardner, Kimberly A Holden, Lax Iyer, Angela Leo Kenyon, Deborah Boles, Scott Parker, Stanley Letovsky, Henry Dong, Narasimhan Nagan, Shakti Ramkissoon, Marcia Eisenberg, Anjen Chenn, Taylor J Jensen
Publikováno v:
Blood. 140:9783
Autor:
Dimitrios Tzachanis, Razelle Kurzrock, Taylor J. Jensen, Amin Haghighat Jahromi, Aaron M. Goodman, Graham McLennan, Marcia Eisenberg, Lisa Kim, Edward D. Ball, Ah Reum Jeong, Carolyn Mulroney, Eyad Almasri, Kimberly A. Holden, Kerry D. Fitzgerald, Carl K. Hoh, Michael Hurley
Publikováno v:
Transplantation and cellular therapy. 28(1)
Methods that enable monitoring of therapeutic efficacy of autologous chimeric antigen receptor (CAR) T-cell therapy will be clinically useful. The aim of this study is to demonstrate the feasibility of blood-derived cell-free DNA (cfDNA) to predict C
Autor:
Taylor J. Jensen, Grant Hogg, Li Cai, Heidi M. Hoffmann, Kimberly A. Holden, Kerry D. Fitzgerald, Angela Kenyon, Michael Mooney, Sabrina Gardner, Wenjie Chen, Narasimhan Nagan, Deborah Boles, Scott Parker, Tamara J. Richman, Stanley Letovsky, Henry Dong, Steven M. Anderson, Marcia Eisenberg, Anjen Chenn
Publikováno v:
Journal of Clinical Oncology. 40:7022-7022
7022 Background: Myeloid neoplasms represent a broad spectrum of hematological disorders for which somatic mutation status in key driver genes is important for diagnosis, prognosis and treatment. Here we summarize the findings from 17,181 clinical sa
Autor:
Josiane P. Lafleur, Graham McLennan, Nathan Faulkner, Susie Brousse, Olga Savichtcheva, Kimberly A. Holden, Taylor J. Jensen, Mark Basik, Adriana Aguilar-Mahecha
Publikováno v:
Cancers
Volume 13
Issue 6
Cancers, Vol 13, Iss 1331, p 1331 (2021)
Volume 13
Issue 6
Cancers, Vol 13, Iss 1331, p 1331 (2021)
Background: Circulating tumor DNA (ctDNA) offers high sensitivity and specificity in metastatic cancer. However, many ctDNA assays rely on specific mutations in recurrent genes or require the sequencing of tumor tissue, difficult to do in a metastati
Autor:
Graham McLennan, Susie Brousse, Mark Basik, Adriana Aguilar-Mahecha, Josiane P. Lafleur, Cristiano Ferrario, Taylor J. Jensen, Kimberly A. Holden
Publikováno v:
Cancer Research. 80:1968-1968
Metastatic breast cancer is mostly incurable and patients are treated with serial chemotherapy regimens to prolong life and decrease symptoms. Treatment efficacy is usually monitored by imaging every 3 months and by the measurement of blood tumor bio
Autor:
Graham McLennan, Nathan Faulkner, Taylor J. Jensen, Kerry D. Fitzgerald, Kimberly A. Holden, Xiaojun Guan, Marcia Eisenberg
Publikováno v:
Cancer Research. 80:1977-1977
Cell-free DNA (cfDNA) derived from tumor cells is present in the plasma of patients with cancer; however, the proportion of this circulating tumor DNA (ctDNA) is typically less than 2%. To overcome this limitation, methods have been developed to bett