Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Kimberly A. Clawson"'
Autor:
Rohit Chugh, Selwyn M. Vickers, Steven J. Skube, Kimberly A. Clawson, Vikas Dudeja, Daniel Borja-Cacho, Ashok K. Saluja, Mara B. Antonoff
Publikováno v:
Journal of Surgical Research. 163:72-78
Background Our recent work demonstrated that treatment of neurobastoma with triptolide causes apoptotic cell death in vitro and decreases tumor size in vivo. Triptolide therapy has been associated with reduced expression of Hsp-70, suggesting a mecha
Autor:
Rohit Chugh, Vikas Dudeja, Kimberly A. Clawson, Selwyn M. Vickers, Nameeta Mujumdar, Rajinder K. Dawra, Y. Yokoyama, Daniel Borja-Cacho, Ashok K. Saluja
Publikováno v:
Journal of Gastrointestinal Surgery. 14:252-260
An emerging therapy in oncology is the induction of apoptotic cell death through anti-death receptor therapy. However, pancreatic cancer is resistant to apoptosis including anti-death receptor therapy. We have previously described how triptolide decr
Autor:
Daniel Borja-Cacho, Selwyn M. Vickers, Mara B. Antonoff, Ashok K. Saluja, Kimberly A. Clawson
Publikováno v:
The Journal of surgical research. 163(2)
Background Cholangiocarcinoma originates from bile duct epithelial cells in the intrahepatic and extrahepatic biliary system. We recently observed that triptolide (a diterpenoid triepoxide) is effective in inducing apoptosis in pancreatic tumors. Dea
Autor:
Daniel A. Saltzman, Kimberly A. Clawson, Ashok K. Saluja, Rohit Chugh, Selwyn M. Vickers, Vikas Dudeja, Brent S. Sorenson, Mara B. Antonoff, Daniel Borja-Cacho, Steven J. Skube
Publikováno v:
Surgery. 146(2)
Background Heat shock protein (Hsp)-70 is overexpressed in several human malignancies, and its inhibition has been shown to kill cancer cells. Our objectives were to assess the effectiveness of triptolide, an Hsp-70 inhibitor, in treating neuroblasto
Publikováno v:
Journal of Surgical Research. 158:340