Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Kimberly A. Broadhurst"'
Autor:
Isabella M. Grumbach, Michelle R. Tamplin, Kimberly A. Broadhurst, Ryuya Hashimoto, Anthony H. Vitale, Randy H. Kardon
Publikováno v:
Translational Vision Science & Technology
Purpose The purpose of this study was to investigate the applicability of laser speckle flowgraphy (LSFG) for a longitudinal study of blood flow parameters in mice before, during, and after continuous infusion of angiotensin-II. Methods Normotensive
Publikováno v:
Clinical and experimental pharmacologyphysiologyREFERENCES. 48(4)
The mechanisms responsible for dysregulation of iron metabolism in response to ethanol ingestion are poorly understood. Relatively brief ethanol exposures in rodents are associated with reduced hepatic hepcidin expression without increases in hepatic
Autor:
Ottar M. Bergmann, Kimberly A. Broadhurst, Kyle E. Brown, Hasan Hicsasmaz, Steven A. Bloomer, Alicia K. Olivier, M. Meleah Mathahs
Publikováno v:
Cell Biochemistry and Function. 34:628-639
Autor:
Steven A, Bloomer, Alicia K, Olivier, Ottar M, Bergmann, M Meleah, Mathahs, Kimberly A, Broadhurst, Hasan, Hicsasmaz, Kyle E, Brown
Publikováno v:
Cell biochemistry and function. 34(8)
Nonalcoholic steatohepatitis is a common liver disease that is often accompanied by dysregulated iron metabolism. The aim of the study was to test the hypothesis that aberrant iron metabolism in nonalcoholic steatohepatitis is modulated by genetic su
Autor:
Neal W. Wilkinson, Kyle E. Brown, Jamie A. Weydert, Okhee Han, Kimberly A. Broadhurst, James R. Howe, Ottar M. Bergmann, Warren N. Schmidt, M. Meleah Mathahs
Publikováno v:
Laboratory Investigation. 88:1349-1357
Hepatic iron deposition unrelated to hereditary hemochromatosis occurs commonly in cirrhosis but the pathogenesis of this condition is unknown. The aim of this study was to compare the expression of genes involved in the regulation of iron metabolism
Publikováno v:
Toxicology and Applied Pharmacology. 223:180-186
Introduction: Oxidative stress can trigger a cellular stress response characterized by induction of antioxidants, acute phase reactants (APRs) and heat shock proteins (HSPs), which are presumed to play a role in limiting tissue damage. In rodents, he
Autor:
Anthony S K Luu, Durga P. Mohapatra, Orlando Lara, Kimberly A Broadhurst, Ana Recober, Heather L. Rossi, Sunny D. Kothari
Publikováno v:
Pain. 157(1)
Obesity is associated with several pain disorders including headache. The effects of obesity on the trigeminal nociceptive system, which mediates headache, remain unknown. We used 2 complementary mouse models of obesity (high-fat diet and leptin defi
Publikováno v:
Translational Research. 148:55-62
Hepatomegaly is commonly observed in hepatic iron overload due to human hemochromatosis and in animal models of iron loading, but the mechanisms underlying liver enlargement in these conditions have received scant attention. In this study, male rats
Publikováno v:
Journal of Surgical Research. 110:188-192
Background. Restraint stress produces gastric hypercontractility and acidity leading to stress ulceration. Intracerebroventricular (ICV) salmon calcitonin (sCT) decreases restraint injury and acidity, but its effects on restraint-induced hypercontrac
Autor:
Joseph J. Cullen, Marilyn M. Hinkhouse, Robert C. Doty, Kimberly A. Broadhurst, Kimberly S. Ephgrave
Publikováno v:
Journal of Surgical Research. 81:81-86
Background. Septic patients are often intolerant of enteral feedings due to a combination of motility disturbances and impaired absorptive function. Our laboratory has previously demonstrated that endotoxemia results in rapid intestinal transit and d