Zobrazeno 1 - 10
of 85
pro vyhledávání: '"Kimberly A Stephens"'
Autor:
David A. Vinson, Kimberly E. Stephens, Robert N. O’Meally, Shri Bhat, Blair C. R. Dancy, Robert N. Cole, Srinivasan Yegnasubramanian, Sean D. Taverna
Publikováno v:
Epigenetics & Chromatin, Vol 15, Iss 1, Pp 1-13 (2022)
Abstract Epigenetic modifications to histone proteins serve an important role in regulating permissive and repressive chromatin states, but despite the identification of many histone PTMs and their perceived role, the epigenetic writers responsible f
Externí odkaz:
https://doaj.org/article/56597f1bd31e400b982987e50e7aab0c
Autor:
Kimberly E. Stephens, Weiqiang Zhou, Zachary Renfro, Zhicheng Ji, Hongkai Ji, Yun Guan, Sean D. Taverna
Publikováno v:
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-16 (2021)
Abstract Background Efforts to understand genetic variability involved in an individual’s susceptibility to chronic pain support a role for upstream regulation by epigenetic mechanisms. Methods To examine the transcriptomic and epigenetic basis of
Externí odkaz:
https://doaj.org/article/2689fd1838d244338a7bd5ef711af79c
Autor:
Lindsay F. Rizzardi, Peter F. Hickey, Adrian Idrizi, Rakel Tryggvadóttir, Colin M. Callahan, Kimberly E. Stephens, Sean D. Taverna, Hao Zhang, Sinan Ramazanoglu, GTEx Consortium, Kasper D. Hansen, Andrew P. Feinberg
Publikováno v:
Genome Biology, Vol 22, Iss 1, Pp 1-26 (2021)
Abstract Background DNA methylation dynamics in the brain are associated with normal development and neuropsychiatric disease and differ across functionally distinct brain regions. Previous studies of genome-wide methylation differences among human b
Externí odkaz:
https://doaj.org/article/fff90ca74fe2430eb0baacf7ea4ca109
Autor:
Kimberly E. Stephens, Weiqiang Zhou, Zhicheng Ji, Zhiyong Chen, Shaoqiu He, Hongkai Ji, Yun Guan, Sean D. Taverna
Publikováno v:
BMC Genomics, Vol 20, Iss 1, Pp 1-18 (2019)
Abstract Background Pain is a subjective experience derived from complex interactions among biological, environmental, and psychosocial pathways. Sex differences in pain sensitivity and chronic pain prevalence are well established. However, the molec
Externí odkaz:
https://doaj.org/article/28fbd83fc0c9493682c1daf8fa8fc938
Autor:
Meher R. Juttukonda, Binyin Li, Randa Almaktoum, Kimberly A. Stephens, Kathryn M. Yochim, Essa Yacoub, Randy L. Buckner, David H. Salat
Publikováno v:
NeuroImage, Vol 230, Iss , Pp 117807- (2021)
Arterial spin labeling (ASL) magnetic resonance imaging (MRI) has become a popular approach for studying cerebral hemodynamics in a range of disorders and has recently been included as part of the Human Connectome Project-Aging (HCP-A). Due to the hi
Externí odkaz:
https://doaj.org/article/8ccf5b72243e400292533ca187b1a234
Publikováno v:
Journal of Clinical and Translational Science, Vol 6, Pp 73-73 (2022)
OBJECTIVES/GOALS: The present work aims to use baseline data to identify demographic, clinical, and psychosocial factors associated with patients who receive analgesic benefit from temporary neurostimulation. METHODS/STUDY POPULATION: This study pres
Externí odkaz:
https://doaj.org/article/59da3821fceb4932ab6f1418dd6f414b
Autor:
Meher R Juttukonda, Kimberly A Stephens, Yi-Fen Yen, Casey M Howard, Jonathan R Polimeni, Bruce R Rosen, David H Salat
Publikováno v:
J Cereb Blood Flow Metab
White matter lesions (WML) have been linked to cognitive decline in aging as well as in Alzheimer’s disease. While hypoperfusion is frequently considered a cause of WMLs due to the resulting reduction in oxygen availability to brain tissue, such re
Autor:
Zhangli Su, Fengbin Wang, Jin-Hee Lee, Kimberly E. Stephens, Romeo Papazyan, Ekaterina Voronina, Kimberly A. Krautkramer, Ana Raman, Jeremy J. Thorpe, Melissa D. Boersma, Vyacheslav I. Kuznetsov, Mitchell D. Miller, Sean D. Taverna, George N. Phillips, John M. Denu
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
KDM4 histone demethylases target specific chromatin regions by a mechanism that is not fully characterised. Here, the authors identify trimethyl-lysine histone-binding preferences for closely related KDM4 double tudor domains and use structural and b
Externí odkaz:
https://doaj.org/article/502865cd91ae47c58370ec2f6dd3787b
Autor:
Eellan Sivanesan, Kimberly E. Stephens, Qian Huang, Zhiyong Chen, Neil C. Ford, Wanru Duan, Shao-Qui He, Xinyan Gao, Bengt Linderoth, Srinivasa N. Raja, Yun Guan
Publikováno v:
PAIN Reports, Vol 4, Iss 5, p e785 (2019)
Abstract. Introduction:. Paclitaxel-induced peripheral neuropathy (PIPN) is a common dose-limiting side effect of this cancer treatment drug. Spinal cord stimulation (SCS) has demonstrated efficacy for attenuating some neuropathic pain conditions. Ob
Externí odkaz:
https://doaj.org/article/9fca326cd81a4334ac777098a149ceb7
Autor:
Eellan Sivanesan, Karla R. Sanchez, Chi Zhang, Shao-Qiu He, Bengt Linderoth, Kimberly E. Stephens, Srinivasa N. Raja, Yun Guan
Publikováno v:
Neuromodulation: Technology at the Neural Interface.