Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Kimberly A Kerr"'
Autor:
Elaine M. Pinheiro, Terrill K. McClanahan, Brian J. Long, Svetlana Sadekova, Razvan Cristescu, Andrey Loboda, Derek Y. Chiang, Lily Y. Moy, Aleksandra K. Olow, Sarah Javaid, Heather A. Hirsch, Kimberly S. Kerr, Wendy M. Blumenschein, Manjiri Sathe, Michael Nebozhyn, Venkataraman Sriram, Jennifer H. Yearley, Hui Xiao, Lan Chen, Michael Caniga, Selvakumar Sukumar, Douglas C. Wilson, Louise Cadzow, Mingmei Cai, Yun Wang, Marlene C. Hinton, Douglas E. Linn, Eric S. Muise, Peter Georgiev
Targeting the programmed death 1/programmed death ligand 1 (PD-1/PD-L1) pathway with immunotherapy has revolutionized the treatment of many cancers. Somatic tumor mutational burden (TMB) and T-cell–inflamed gene expression profile (GEP) are clinica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afdb5d08b628c9801815bfadb0bfe628
https://doi.org/10.1158/1535-7163.c.6543385.v1
https://doi.org/10.1158/1535-7163.c.6543385.v1
Autor:
Elaine M. Pinheiro, Terrill K. McClanahan, Brian J. Long, Svetlana Sadekova, Razvan Cristescu, Andrey Loboda, Derek Y. Chiang, Lily Y. Moy, Aleksandra K. Olow, Sarah Javaid, Heather A. Hirsch, Kimberly S. Kerr, Wendy M. Blumenschein, Manjiri Sathe, Michael Nebozhyn, Venkataraman Sriram, Jennifer H. Yearley, Hui Xiao, Lan Chen, Michael Caniga, Selvakumar Sukumar, Douglas C. Wilson, Louise Cadzow, Mingmei Cai, Yun Wang, Marlene C. Hinton, Douglas E. Linn, Eric S. Muise, Peter Georgiev
Supplementary Data from Reverse Translating Molecular Determinants of Anti–Programmed Death 1 Immunotherapy Response in Mouse Syngeneic Tumor Models
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::681228ea71eeffe6a5d955b9c8768f68
https://doi.org/10.1158/1535-7163.22522450
https://doi.org/10.1158/1535-7163.22522450
Autor:
Peter Georgiev, Eric S. Muise, Douglas E. Linn, Marlene C. Hinton, Yun Wang, Mingmei Cai, Louise Cadzow, Douglas C. Wilson, Selvakumar Sukumar, Michael Caniga, Lan Chen, Hui Xiao, Jennifer H. Yearley, Venkataraman Sriram, Michael Nebozhyn, Manjiri Sathe, Wendy M. Blumenschein, Kimberly S. Kerr, Heather A. Hirsch, Sarah Javaid, Aleksandra K. Olow, Lily Y. Moy, Derek Y. Chiang, Andrey Loboda, Razvan Cristescu, Svetlana Sadekova, Brian J. Long, Terrill K. McClanahan, Elaine M. Pinheiro
Publikováno v:
Molecular Cancer Therapeutics. 21:427-439
Targeting the programmed death 1/programmed death ligand 1 (PD-1/PD-L1) pathway with immunotherapy has revolutionized the treatment of many cancers. Somatic tumor mutational burden (TMB) and T-cell–inflamed gene expression profile (GEP) are clinica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f195b533efd20f8c25094ce9564cd84c
https://doi.org/10.1158/1535-7163.mct-21-0561
https://doi.org/10.1158/1535-7163.mct-21-0561
Autor:
Lutz Kockel, Kimberly S Kerr, Michael Melnick, Katja Brückner, Matthias Hebrok, Norbert Perrimon
Publikováno v:
PLoS Genetics, Vol 6, Iss 6, p e1000990 (2010)
Akt represents a nodal point between the Insulin receptor and TOR signaling, and its activation by phosphorylation controls cell proliferation, cell size, and metabolism. The activity of Akt must be carefully balanced, as increased Akt signaling is f
Externí odkaz:
https://doaj.org/article/bb54d020547f433fb102547d41b03397
Autor:
Neal X. Chen, Mark A. Deeg, Steven J. Miller, Carlos A. Labarrere, William C Watson, Joseph L. Unthank, Kimberly A Kerr
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 293:H2634-H2643
Recent studies have established that age is the major risk factor for vascular disease. Numerous aberrant changes occur in vascular structure and function during aging, and animal models are the primary means to determine the underlying mechanisms of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f4b478ae37ee9333d3995a50197d9b5
https://doi.org/10.1152/ajpheart.00397.2007
https://doi.org/10.1152/ajpheart.00397.2007
Publikováno v:
Anesthesiology. 103:65-73
Background: Dysfunctional mitochondria have been widely accepted as one of the key targets and a mediator of secondary cell injury and organ failure during hemorrhagic shock (HS). The liver is known to be the first organ to display the signs of injur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96182fb67ebda4bc39eb12915e3b07e2
https://doi.org/10.1097/00000542-200507000-00013
https://doi.org/10.1097/00000542-200507000-00013
Autor:
Yuly Fuentes-Medel, James A. Ashley, Marc R. Freeman, Amy E. Sheehan, Cassandra Brewer, Kimberly S. Kerr, Vivian Budnik, Katharine C. Abruzzi, Ozge E. Tasdemir-Yilmaz, Romina Barria
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 34(8)
Glial cells are emerging as important regulators of synapse formation, maturation, and plasticity through the release of secreted signaling molecules. Here we use chromatin immunoprecipitation along withDrosophilagenomic tiling arrays to define poten
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8184d39fe86bc08ab58f9be371f0345
https://pubmed.ncbi.nlm.nih.gov/24553932
https://pubmed.ncbi.nlm.nih.gov/24553932
Autor:
Kimberly A Kerr, Robert V. Considine, Qihong Zhu, RoseMarie Jones, William R. Watson, Beth E. Juliar, Jason E. Bovenkerk, Mikako Degawa-Yamauchi
Publikováno v:
The Journal of clinical endocrinology and metabolism. 88(11)
The role of resistin in obesity and insulin resistance in humans is controversial. Therefore, resistin protein was quantitated by ELISA in serum of 27 lean [13 women/14 men, body mass index (BMI) 21.7 ± 0.4 kg/m2, age 33 ± 2 yr] and 50 obese (37 wo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d21e8985bd3994f9e6866bd9615a28b
https://pubmed.ncbi.nlm.nih.gov/15070974
https://pubmed.ncbi.nlm.nih.gov/15070974
Autor:
B. Paul Herring, Jay L. Tuttle, Joseph L. Unthank, Kimberly A Kerr, Bridget M. Sanders, Michael C. Dalsing, Harold M. Burkhart, Steven W. Fath, William C Watson
Publikováno v:
Microcirculation (New York, N.Y. : 1994). 9(5)
Objective: To determine whether collateral artery development is impaired in spontaneously hypertensive (SHR) relative to normotensive (WKY) rats. Methods: Sequential mesenteric arteries were ligated to create a collateral pathway responsible for the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c75e669792bfd522e2c8b5c060539ce
https://pubmed.ncbi.nlm.nih.gov/12375172
https://pubmed.ncbi.nlm.nih.gov/12375172
Autor:
Robert V. Considine, William R. Watson, Beth E. Juliar, Jason E. Bovenkerk, Mikako Degawa-Yamauchi, RoseMarie Jones, Kimberly A Kerr
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 89:1977-1978
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cef2f279146897f3345e5d4af5ea0c45
https://doi.org/10.1210/jc.2003-032253
https://doi.org/10.1210/jc.2003-032253