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pro vyhledávání: '"Kimberly A, Frizzell"'
Autor:
Jonathan O, Nelson, Dominique, Förster, Kimberly A, Frizzell, Stefan, Luschnig, Mark M, Metzstein
Publikováno v:
Genetics. 209(4)
The nonsense-mediated messenger RNA (mRNA) decay (NMD) pathway is a cellular quality control and post-transcriptional gene regulatory mechanism and is essential for viability in most multicellular organisms . A complex of proteins has been identified
Autor:
Harmit S. Malik, Nitin Phadnis, Aida Flor A. de la Cruz, Emily Hsieh, Kimberly A. Frizzell, EmilyClare P. Baker, Jay Shendure, Jacob O. Kitzman, Jacob C Cooper
Publikováno v:
Science. 350:1552-1555
Essential genes and species incompatibilities Crosses between two fruit fly species, Drosophila melanogaster and D. simulans , result in hybrid progeny that are all female. Although some of the genes responsible for this species barrier are known, th
Publikováno v:
G3: Genes|Genomes|Genetics
Endoplasmic reticulum (ER) stress results from an imbalance between the load of proteins entering the secretory pathway and the ability of the ER to fold and process them. The response to ER stress is mediated by a collection of signaling pathways te
Publikováno v:
RNA. 18:1475-1486
The nonsense-mediated mRNA decay (NMD) pathway is best known for targeting mutant mRNAs containing premature termination codons for rapid degradation, but it is also required for regulation of many endogenous transcripts. Components of the NMD pathwa