Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Kimberly, Walter"'
Autor:
Lixia Wang, John Powderly, Tanios Bekaii-Saab, Susanna Ulahannan, Ngan Nguyen, Deborah Doroshow, Yan Xing, Mark Whidden, Carl Millward, Jonathan Benjamin, S John Weroha, Frances Valdes-Albini, Kimberly Walter, Andrew Wrong, Paul Del Castillo, Steven Isakoff
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/03e0ba082d824a39b3cb3ba0fcab7adb
Autor:
James D Joseph, Beatrice Darimont, Wei Zhou, Alfonso Arrazate, Amy Young, Ellen Ingalla, Kimberly Walter, Robert A Blake, Jim Nonomiya, Zhengyu Guan, Lorna Kategaya, Steven P Govek, Andiliy G Lai, Mehmet Kahraman, Dan Brigham, John Sensintaffar, Nhin Lu, Gang Shao, Jing Qian, Kate Grillot, Michael Moon, Rene Prudente, Eric Bischoff, Kyoung-Jin Lee, Celine Bonnefous, Karensa L Douglas, Jackaline D Julien, Johnny Y Nagasawa, Anna Aparicio, Josh Kaufman, Benjamin Haley, Jennifer M Giltnane, Ingrid E Wertz, Mark R Lackner, Michelle A Nannini, Deepak Sampath, Luis Schwarz, Henry Charles Manning, Mohammed Noor Tantawy, Carlos L Arteaga, Richard A Heyman, Peter J Rix, Lori Friedman, Nicholas D Smith, Ciara Metcalfe, Jeffrey H Hager
Publikováno v:
eLife, Vol 8 (2019)
Externí odkaz:
https://doaj.org/article/d1935c5b03e6433ea06acf491e7dc6f2
Autor:
Michael Goggins, Michael Borges, Kimberly Walter, Seung-Mo Hong, Ang Li, Audrey Vincent, Margaret Griffith, Noriyuki Omura
Supplementary Figures S1-S3 and Supplementary Tables S1-S2.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a59f7e104eb064d20560a4eb5b3888f
https://doi.org/10.1158/1541-7786.22519341
https://doi.org/10.1158/1541-7786.22519341
Autor:
Jill M. Spoerke, Steven Gendreau, Kimberly Walter, Jiaheng Qiu, Timothy R. Wilson, Heidi Savage, Junko Aimi, Mika K. Derynck, Meng Chen, Iris T. Chan, Lukas C. Amler, Garret M. Hampton, Stephen Johnston, Ian Krop, Peter Schmid, Mark R. Lackner
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
Fulvestrant degrades the oestrogen receptor. Here, the authors report on a clinical trial using fulvestrant and show that mutations in the oestrogen receptor alpha gene are prevalent in circulating tumour DNA and do not influence the clinical outcome
Externí odkaz:
https://doaj.org/article/3ed6583a52b645a290a897ba20ac7a5f
Autor:
Lisa D. Belmont, Hartmut Koeppen, Richard Bourgon, Thomas O'Brien, Robert L. Yauch, Xiaorong Liang, Bianca Liederer, Peter M. Haverty, Thinh Pham, Yang Xiao, Dane Mohl, Pan Du, Thomas Holcomb, Kimberly Walter, Kristi Elkins, David S. Shames
Purpose: We sought to identify predictive biomarkers for a novel nicotinamide phosphoribosyltransferase (NAMPT) inhibitor.Experimental Design: We use a NAMPT inhibitor, GNE-617, to evaluate nicotinic acid rescue status in a panel of more than 400 can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e84aa7961f32a2031d250e784a4c317
https://doi.org/10.1158/1078-0432.c.6520628.v1
https://doi.org/10.1158/1078-0432.c.6520628.v1
Autor:
Michael Goggins, Michael Borges, Audrey Vincent, Margaret Griffith, Seung-Mo Hong, Noriyuki Omura, Kimberly Walter
Supplementary Data from Overexpression of Smoothened Activates the Sonic Hedgehog Signaling Pathway in Pancreatic Cancer–Associated Fibroblasts
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d22bb7444a666bac5ff57892a8ff711
https://doi.org/10.1158/1078-0432.22440027
https://doi.org/10.1158/1078-0432.22440027
Autor:
Lisa D. Belmont, Hartmut Koeppen, Richard Bourgon, Thomas O'Brien, Robert L. Yauch, Xiaorong Liang, Bianca Liederer, Peter M. Haverty, Thinh Pham, Yang Xiao, Dane Mohl, Pan Du, Thomas Holcomb, Kimberly Walter, Kristi Elkins, David S. Shames
PDF file 122K, A) Chemical structure of GNE-617, B) cellular NAD and ATP levels in H522 cells after exposure to 4nM GNE-617, C) correlation of NAPRT1 mRNA and protein (n=32, spearman r= 0.88, p,0.0001)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3078920a930d4fcc697360aeedd937c0
https://doi.org/10.1158/1078-0432.22446035
https://doi.org/10.1158/1078-0432.22446035
Autor:
Michael Goggins, Michael Borges, Audrey Vincent, Margaret Griffith, Seung-Mo Hong, Noriyuki Omura, Kimberly Walter
Purpose: Accumulating evidence suggests that cancer-associated stromal fibroblasts (CAF) contribute to tumor growth by actively communicating with cancer cells. Our aim is to identify signaling pathways involved in tumor-stromal cell interactions in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15f69a290ad0587f42d58afbd4f093a1
https://doi.org/10.1158/1078-0432.c.6517407
https://doi.org/10.1158/1078-0432.c.6517407
Autor:
Lisa D. Belmont, Hartmut Koeppen, Richard Bourgon, Thomas O'Brien, Robert L. Yauch, Xiaorong Liang, Bianca Liederer, Peter M. Haverty, Thinh Pham, Yang Xiao, Dane Mohl, Pan Du, Thomas Holcomb, Kimberly Walter, Kristi Elkins, David S. Shames
PDF file 141K, Supplementary methods for NAD quantification and the QMSP assay. Table S1 GNE-617 IC50 and mRNA Levels of NAMPT and NAPRT1, Table S2 Cell Lines Not Rescued with 10uM NA, Table S3 Cell Lines with Low NAPRT1 Expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ead523cff3b9f9c55d3f8c544a360c9
https://doi.org/10.1158/1078-0432.22446032.v1
https://doi.org/10.1158/1078-0432.22446032.v1
Autor:
Michael Goggins, Michael Borges, Margaret Griffith, Kimberly Walter, Audrey Vincent, Seung-Mo Hong, Noriyuki Omura, Ang Li
Supplementary Tables 1-2 from Pancreatic Cancers Epigenetically Silence SIP1 and Hypomethylate and Overexpress miR-200a/200b in Association with Elevated Circulating miR-200a and miR-200b Levels
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f488343203cd1f7d9113bb9504c8343
https://doi.org/10.1158/0008-5472.22383444
https://doi.org/10.1158/0008-5472.22383444