Výsledky vyhledávání - "Kimberly, Steinmann"

Human plasma‐derived alpha1‐proteinase inhibitor in patients with new‐onset type 1 diabetes mellitus: A randomized, placebo‐controlled proof‐of‐concept study

Autor: William H. Lagarde, Eva Tsalikian, Kimberly Steinmann, Barry Reiner, Steven M. Willi, Kecia L. Courtney

Publikováno v: Pediatric Diabetes

Background While circulating levels of alpha1‐proteinase inhibitor (alpha1‐PI) are typically normal, antiprotease activity appears to be compromised in patients with Type 1 diabetes mellitus (T1DM). Because alpha1‐PI [human] (alpha1‐PI[h]) th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08a4f2a395371627eefdb01a08bfa44a
http://europepmc.org/articles/PMC7984376

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Safety and pharmacokinetics of Alpha-1 MP (Prolastin®-C) in Japanese patients with alpha1-antitrypsin (AAT) deficiency

Autor: Masaharu Nishimura, Masaru Suzuki, Junliang Chen, Kazuhisa Takahashi, Kimberly Steinmann, Satoshi Konno, Toshihiro Nukiwa, Susan C. Sorrells, Tadashi Sato, Ken-ichi Hayashi, Kuniaki Seyama

Publikováno v: Respiratory Investigation. 57:89-96

Background Alpha1-Proteinase Inhibitor, Modified Process (Alpha-1 MP) is used for augmentation therapy in alpha1-antitrypsin deficiency (AATD), an extremely rare disease in Japan. Weekly doses of 60 mg/kg Alpha-1 MP have been shown to be safe and wel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f64ca673738868c50e20d1dfda9e9244
https://doi.org/10.1016/j.resinv.2018.09.006

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An Ecoinformatics Approach to Field-Scale Evaluation of Insecticide Effects in California Citrus: Are Citrus Thrips and Citrus Red Mite Induced Pests?

Autor: Lindsey M Hack, George Livingston, Kimberly Steinmann, Elizabeth E. Grafton-Cardwell, Jay A. Rosenheim

Publikováno v: Journal of Economic Entomology. 111:1290-1297

Experimental approaches to studying the consequences of pesticide use, including impacts on beneficial insects, are vital; however, they can be limited in scale and realism. We show that an ecoinformatics approach that leverages existing data on pest

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38bfa5d4c9b61c80be19765c63a33748
https://doi.org/10.1093/jee/toy067

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Bioequivalence of a Liquid Formulation of Alpha1-Proteinase Inhibitor Compared with Prolastin®-C (Lyophilized Alpha1-PI) in Alpha1-Antitrypsin Deficiency

Autor: Susan C. Sorrells, Alan F. Barker, Douglas Lee, Michael Campos, Robert A. Sandhaus, Jiang Lin, Mark L. Brantly, Kimberly Steinmann, James M. Stocks

Publikováno v: COPD: Journal of Chronic Obstructive Pulmonary Disease. 14:590-596

This study evaluated the bioequivalence, safety, and immunogenicity of a new liquid formulation of human plasma–derived alpha1-proteinase inhibitor, Liquid Alpha1-PI, compared with the Lyophilized ...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::47347a0e6949ddb170b737eaaf65ccc9
https://doi.org/10.1080/15412555.2017.1376044

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Variation in pesticide use across crops in California agriculture: Economic and ecological drivers

Autor: Hanna M Kahl, Jay A. Rosenheim, Kimberly Steinmann, Bodil N. Cass

Publikováno v: Science of The Total Environment. 733:138683

Pesticide use is a key component of efficient crop production, but is associated with a suite of costs. Understanding the main drivers of pesticide use will help us target research to develop effective alternatives. Although economic models predict,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::354d12600e5a596482a1dcadb6a6ea15
https://doi.org/10.1016/j.scitotenv.2020.138683

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Safety and pharmacokinetics of Alpha-1 MP (Prolastin

Autor: Kuniaki, Seyama, Toshihiro, Nukiwa, Tadashi, Sato, Masaru, Suzuki, Satoshi, Konno, Kazuhisa, Takahashi, Masaharu, Nishimura, Kimberly, Steinmann, Susan, Sorrells, Junliang, Chen, Ken-Ichi, Hayashi

Publikováno v: Respiratory investigation. 57(1)

AlphaThis was a multicenter, open-label trial in Japanese adults aged ≥20 years with AATD. Samples for evaluation of serum alphaFour subjects were analyzed. The median tThe PK and safety of Alpha-1 MP in Japanese subjects with AATD were consistent

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::113bd154855b20de928111033d820878
https://pubmed.ncbi.nlm.nih.gov/30416054

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