Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Kimberley T. McLean"'
Autor:
Amy L. Burns, Brad E. Sleebs, Maria Gancheva, Kimberley T. McLean, Ghizal Siddiqui, Henrietta Venter, James G. Beeson, Ryan O’Handley, Darren J. Creek, Shutao Ma, Sonja Frölich, Christopher D. Goodman, Geoffrey I. McFadden, Danny W. Wilson
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
IntroductionThe spread of artemisinin resistant Plasmodium falciparum parasites is of global concern and highlights the need to identify new antimalarials for future treatments. Azithromycin, a macrolide antibiotic used clinically against malaria, ki
Externí odkaz:
https://doaj.org/article/09251fb382a0406ab2e4670017894854
Autor:
Shannon C. David, Erin B. Brazel, Eve V. Singleton, Vikrant Minhas, Zoe Laan, Catherine Scougall, Austen Y. Chen, Hui Wang, Chloe J. Gates, Kimberley T. McLean, Jeremy S. Brown, Giuseppe Ercoli, Rachel A. Higgins, Paul V. Licciardi, Kim Mulholland, Justin B. Davies, Timothy R. Hirst, James C. Paton, Mohammed Alsharifi
Publikováno v:
mBio, Vol 13, Iss 5 (2022)
ABSTRACT Streptococcus pneumoniae (Spn) remains a major cause of global mortality, with extensive antigenic diversity between capsular serotypes that poses an ongoing challenge for vaccine development. Widespread use of pneumococcal conjugate vaccine
Externí odkaz:
https://doaj.org/article/511cd819d0a5443389dd8f6cbe5374df
Autor:
Hannah N. Agnew, Erin B. Brazel, Alexandra Tikhomirova, Mark van der Linden, Kimberley T. McLean, James C. Paton, Claudia Trappetti
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Streptococcus pneumoniae is the leading cause of bacterial paediatric meningitis after the neonatal period worldwide, but the bacterial factors and pathophysiology that drive pneumococcal meningitis are not fully understood. In this work, we have ide
Externí odkaz:
https://doaj.org/article/4cc47e2da4fb452bbcb8af1819fdaad2
Autor:
Maoge Zang, Hugo MacDermott-Opeskin, Felise G. Adams, Varsha Naidu, Jack K. Waters, Ashley B. Carey, Alex Ashenden, Kimberley T. McLean, Erin B. Brazel, Jhih-Hang Jiang, Alessandra Panizza, Claudia Trappetti, James C. Paton, Anton Y. Peleg, Ingo Köper, Ian T. Paulsen, Karl A. Hassan, Megan L. O’Mara, Bart A. Eijkelkamp
Publikováno v:
mBio, Vol 12, Iss 3 (2021)
Antimicrobial resistance is an emerging global health crisis. Consequently, we have a critical need to prolong our current arsenal of antibiotics, in addition to the development of novel treatment options.
Externí odkaz:
https://doaj.org/article/6d0881cf57d441f7bee271a358bfc5d7
Autor:
Alexandra Tikhomirova, Erin B. Brazel, Kimberley T. McLean, Hannah N. Agnew, James C. Paton, Claudia Trappetti
Publikováno v:
Pathogens, Vol 11, Iss 2, p 216 (2022)
The LuxS protein, encoded by luxS, is required for the production of autoinducer 2 (AI-2) in Streptococcus pneumoniae. The AI-2 molecule serves as a quorum sensing signal, and thus regulates cellular processes such as carbohydrate utilisation and bio
Externí odkaz:
https://doaj.org/article/f4e41ea4414940ccb18aec82d37031f1
Autor:
Alexandra, Tikhomirova, Erin B, Brazel, Kimberley T, McLean, Hannah N, Agnew, James C, Paton, Claudia, Trappetti
Publikováno v:
Pathogens (Basel, Switzerland). 11(2)
The LuxS protein, encoded by
Autor:
Vikrant Minhas, Salomé Legendre, James C. Paton, Kimberley T. McLean, Claudia Trappetti, Erin B. Brazel, Gian Haasbroek, Alexandra Tikhomirova
Publikováno v:
J Bacteriol
Streptococcus pneumoniae (the pneumococcus) is a formidable human pathogen that is capable of asymptomatically colonizing the nasopharynx. Progression from colonization to invasive disease involves adaptation to distinct host niches, which vary marke
Autor:
Kimberley T. McLean, Shannon C. David, James C. Paton, Iain Comerford, Lauren J. McAllister, Jan-Willem Veening, Claudia Trappetti, Vikrant Minhas, Shaun R. McColl, Hui Wang, Rieza Aprianto
Publikováno v:
Communications biology, vol. 3, no. 1, pp. 293
Communications Biology, Vol 3, Iss 1, Pp 1-12 (2020)
Communications Biology
Communications Biology, Vol 3, Iss 1, Pp 1-12 (2020)
Communications Biology
Streptococcus pneumoniae is a genetically diverse human-adapted pathogen commonly carried asymptomatically in the nasopharynx. We have recently shown that a single nucleotide polymorphism (SNP) in the raffinose pathway regulatory gene rafR accounts f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efe68ee42a08e10e08d61f61bab8c04a
https://serval.unil.ch/resource/serval:BIB_AA4F7869B18E.P001/REF.pdf
https://serval.unil.ch/resource/serval:BIB_AA4F7869B18E.P001/REF.pdf
Autor:
Kimberley T. McLean, Shannon C. David, Claudia Trappetti, James C. Paton, Hui Wang, Rieza Aprianto, Vikrant Minhas, Lauren J. McAllister, Jan-Willem Veening, Shaun R. McColl, Iain Comerford
Streptococcus pneumoniae is a genetically diverse human-adapted pathogen commonly carried asymptomatically in the nasopharynx. We have recently shown that a single nucleotide polymorphism (SNP) in the raffinose pathway regulatory gene rafR accounts f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55d444942bda8410047927c683865ee8