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pro vyhledávání: '"Kimberley Solomon"'
Autor:
Kimberley Solomon, George L. Trainor, Maryanne B. Covington, Melissa Estrella, Robert C. Newton, Joseph B. Santella, Nicole Stowell, Paul S. Watson, Cheryl M. Clark, Jeffrey G. Varnes, Paul Davies, John V. Duncia, Eric A. Wadman, Carl P. Decicco, Gardner Daniel S, Patricia K. Welch, Soo S. Ko, Dean A. Wacker
Publikováno v:
Bioorganicmedicinal chemistry letters. 14(7)
The discovery of novel and selective small molecule antagonists of the CC Chemokine Receptor-3 (CCR3) is presented. Simple conversion from a 4- to 3-benzylpiperidine gave improved selectivity for CCR3 over the serotonin 5HT(2A) receptor. Chiral resol