Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Kimberley L. Alexander"'
Publikováno v:
Journal of Extracellular Vesicles, Vol 11, Iss 10, Pp n/a-n/a (2022)
Abstract Extracellular vesicles (EVs) are lipid‐membrane enclosed nanoparticles that play significant roles in health and disease. EVs are abundant in body fluids and carry an array of molecules (proteins, lipids, nucleic acids and glycans) that re
Externí odkaz:
https://doaj.org/article/f8bad14c89c44ad68bc700415faec0c7
Autor:
Susannah Hallal, Saeideh Ebrahim Khani, Heng Wei, Maggie Yuk Ting Lee, Hao-Wen Sim, Joanne Sy, Brindha Shivalingam, Michael E. Buckland, Kimberley L. Alexander-Kaufman
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 14, p 4954 (2020)
Extracellular vesicles (EVs) play key roles in glioblastoma (GBM; astrocytoma grade IV) biology and are novel sources of biomarkers. EVs released from GBM tumors can cross the blood-brain-barrier into the periphery carrying GBM molecules, including s
Externí odkaz:
https://doaj.org/article/26f19f3966904b16adb25f6450ecd880
Autor:
Islam Alzoubi, Guoqing Bao, Rong Zhang, Christina Loh, Yuqi Zheng, Svetlana Cherepanoff, Gary Gracie, Maggie Lee, Michael Kuligowski, Kimberley L. Alexander, Michael E. Buckland, Xiuying Wang, Manuel B. Graeber
Publikováno v:
Cancers; Volume 14; Issue 14; Pages: 3441
Routine examination of entire histological slides at cellular resolution poses a significant if not insurmountable challenge to human observers. However, high-resolution data such as the cellular distribution of proteins in tissues, e.g., those obtai
Autor:
Ágota Tűzesi, Susannah Hallal, Laveniya Satgunaseelan, Michael E. Buckland, Kimberley L. Alexander
Publikováno v:
Cancers. 15:1232
RNA modifications are diverse, dynamic, and reversible transcript alterations rapidly gaining attention due to their newly defined RNA regulatory roles in cellular pathways and pathogenic mechanisms. The exciting emerging field of ‘epitranscriptomi
Publikováno v:
F1000Research. 12:52
Glioblastoma (GBM) is the most aggressive form of primary brain cancer, with 5-year survival rates of less than 5%. Clinical management of GBM has not changed in the last 15 years, and current treatment approaches combine surgical resection, followed
Autor:
Christine L Paul, Hubert Hondermarck, James Lynam, Cassandra P Griffin, Marjorie M. Walker, Kimberley L Alexander
Publikováno v:
Neuro-oncology Advances
There have been limited improvements in diagnosis, treatment, and outcomes of primary brain cancers, including glioblastoma, over the past 10 years. This is largely attributable to persistent deficits in understanding brain tumor biology and pathogen
Autor:
Alexander Yuile, Laveniya Satgunaseelan, Kimberley L Alexander, Subotheni Thavaneswaran, Michael Krasovitsky, Michael Buckland, Maggie Lee, Grace Wei, Marina Kastelan, Mark Wong, Isabella Wilson, Angela Bayly, Winny Varikat, Hao-Wen Sim, Ben Kong, Zarnie Lwin, Cassie Turner, Michael Back, Samuel Miller, Adrian Lee, Helen Wheeler
Publikováno v:
Neuro-Oncology. 24:vii41-vii41
BACKGROUND IDH-mutant astrocytomas with CDKN2A/B homozygous deletions (HD) are now categorized as grade 4 astrocytomas. It is unclear how these HD astrocytomas should be treated. We aimed to compare 3-year outcomes for HD versus heterozygous deleted
Autor:
Brindha Shivalingam, Michael E. Buckland, Joanne Sy, Susannah Hallal, Hao-Wen Sim, Heng Wei, Kimberley L Alexander-Kaufman, Saeideh Ebrahim Khani, Maggie Lee
Publikováno v:
International Journal of Molecular Sciences
Volume 21
Issue 14
International Journal of Molecular Sciences, Vol 21, Iss 4954, p 4954 (2020)
Volume 21
Issue 14
International Journal of Molecular Sciences, Vol 21, Iss 4954, p 4954 (2020)
Extracellular vesicles (EVs) play key roles in glioblastoma (GBM
astrocytoma grade IV) biology and are novel sources of biomarkers. EVs released from GBM tumors can cross the blood-brain-barrier into the periphery carrying GBM molecules, includi
astrocytoma grade IV) biology and are novel sources of biomarkers. EVs released from GBM tumors can cross the blood-brain-barrier into the periphery carrying GBM molecules, includi