Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Kimberley Joanne Hatfield"'
Publikováno v:
Biomedicines, Vol 10, Iss 8, p 1881 (2022)
The prognosis of acute myeloid leukemia (AML) is poor, especially for the elderly population. Targeted therapy with small molecules may be a potential strategy to overcome chemoresistance and improve survival in AML. We investigated the inhibition of
Externí odkaz:
https://doaj.org/article/5ab618bf5a73480392dce1742978b747
Autor:
Håkon Reikvam, Kimberley Joanne Hatfield, Øystein Wendelbo, Roald Lindås, Philippe Lassalle, Øystein Bruserud
Publikováno v:
Biomolecules, Vol 12, Iss 4, p 492 (2022)
Endocan is a soluble dermatan sulfate proteoglycan expressed by endothelial cells and detected in serum/plasma. Its expression is increased in tumors/tumor vessels in several human malignancies, and high expression (high serum/plasma levels or tumor
Externí odkaz:
https://doaj.org/article/3f1cf9c0c8d14957bd9c801183b67a65
Autor:
Ida Sofie Grønningsæter, Håkon Reikvam, Elise Aasebø, Sushma Bartaula-Brevik, Tor Henrik Tvedt, Øystein Bruserud, Kimberley Joanne Hatfield
Publikováno v:
Cells, Vol 9, Iss 5, p 1155 (2020)
Acute myeloid leukemia (AML) is an aggressive blood cancer resulting in accumulation of immature, dysfunctional blood cells in the bone marrow. Changes in cell metabolism are features of many cancers, including AML and this may be exploited as a ther
Externí odkaz:
https://doaj.org/article/5f40a3c0e3e740798134cb98273fe632
Autor:
Håkon Reikvam, Annette K. Brenner, Karen Marie Hagen, Knut Liseth, Silje Skrede, Kimberley Joanne Hatfield, Øystein Bruserud
Publikováno v:
Stem Cell Research, Vol 15, Iss 3, Pp 530-541 (2015)
Interactions between acute myeloid leukemia (AML) blasts and neighboring stromal cells are important for disease development and chemosensitivity. However, the molecular mechanisms involved in the cytokine-mediated crosstalk between mesenchymal stem
Externí odkaz:
https://doaj.org/article/c61cd7b682824ae29c989f9a8eba5eb0
Autor:
Ida Sofie Grønningsæter, Hanne Kristin Fredly, Bjørn Tore Gjertsen, Kimberley Joanne Hatfield, Øystein Bruserud
Publikováno v:
Cells, Vol 8, Iss 10, p 1229 (2019)
Acute myeloid leukemia (AML) is an aggressive malignancy, and many elderly/unfit patients cannot receive intensive and potentially curative therapy. These patients receive low-toxicity disease-stabilizing treatment. The combination of all-trans retin
Externí odkaz:
https://doaj.org/article/419f4a8262fe4aef8f2d95ea15a1dcaf
Autor:
Roald Lindås, Tor Henrik Andersson Tvedt, Kimberley Joanne Hatfield, Håkon Reikvam, Øystein Bruserud
Publikováno v:
Journal of Transplantation, Vol 2014 (2014)
Endothelial cells are involved in the pathogenesis of acute graft-versus-host disease (GVHD) after allogeneic stem cell transplantation. These cells express several molecules that can be detected as biologically active soluble forms; serum levels of
Externí odkaz:
https://doaj.org/article/9dff82aec6c942b2963460712740d8b0
Autor:
Marte Karen Brattås, Anette Lodvir Hemsing, Kristin Paulsen Rye, Kimberley Joanne Hatfield, Håkon Reikvam
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 23; Pages: 14706
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Acute myeloid leukemia (AML) is an aggressive hematological malignancy with a dismal prognosis. The cytoplasmic spleen tyrosine kinase (SYK) is highly expressed by hematopoietic cells and has emerged as a potential therapeutic target. In this study,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1ef813bb066c1da5eb5b425f47a48a5
Publikováno v:
Current Medical Research and Opinion. 37:2107-2111
Acute myeloid leukemia (AML) is a highly malignant blood cancer disease, with dismal prognosis. The theory that cancer cells utilize metabolism to their growth advantage was postulated almost hundred years ago. However, only recently have been able t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a5a39ec48a17dc866cc45c819544e96
https://doi.org/10.1080/03007995.2021.1978960
https://doi.org/10.1080/03007995.2021.1978960
Autor:
Håkon Reikvam, Anh Khoi Vo, Silje Johansen, Anette Lodvir Hemsing, Magne Haugland Solheim, Knut Anders Mosevoll, Tor Henrik Anderson Tvedt, Kimberley Joanne Hatfield
Publikováno v:
Blood Advances
Chronic graft-versus-host disease (cGVHD) is the most common long-term complication of allogeneic hematopoietic stem cell transplantation (allo-HSCT). During the last decade, the interest of micro RNAs (miRNAs) in the pathophysiological process of cG
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::454a3455415fb0f714b1ffe152b67871
https://hdl.handle.net/11250/3028672
https://hdl.handle.net/11250/3028672
Autor:
Håkon Reikvam, Ida Sofie Grønningsæter, Frode S. Berven, Øystein Bruserud, Maria Hernandez-Valladares, Sushma Bartaula-Brevik, Kimberley Joanne Hatfield, Frode Selheim, Tor Henrik Anderson Tvedt, Elise Aasebø
Publikováno v:
Journal of Personalized Medicine, Vol 11, Iss 779, p 779 (2021)
Journal of Personalized Medicine
Journal of Personalized Medicine
Autophagy is a highly conserved cellular degradation process that prevents cell damage and promotes cell survival, and clinical efforts have exploited autophagy inhibition as a therapeutic strategy in cancer. Chloroquine is a well-known antimalarial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b2ec025f54cdd827686227f7efd21d9
https://www.mdpi.com/2075-4426/11/8/779
https://www.mdpi.com/2075-4426/11/8/779