Výsledky vyhledávání - "Kimberley Glover"

Mutation of Nonessential Cysteines Shows That the NF-κB Essential Modulator Forms a Constitutive Noncovalent Dimer That Binds IκB Kinase-β with High Affinity

Autor: Kimberley Glover, Thomas D. Gilmore, Melanie Herscovitch, Thomas Ennis, Shaun M. Cote, Rishitha Bollam, Urs Weber, Mary S. Golden, Robert Shaffer, Adrian Whitty, Karen N. Allen

Publikováno v: Biochemistry. 52:9141-9154

NEMO (NF-κB essential modulator) associates with catalytic subunits IKKα and IKKβ to form the IκB kinase (IKK) complex and is a key regulator of NF-κB pathway signaling. Biochemical and structural characterization of NEMO has been challenging, h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f3646f379872b9cff5d42638ba351a1
https://doi.org/10.1021/bi401368r

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