Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Kimberley A Pitman"'
Autor:
Megan O'Rourke, Carlie L Cullen, Loic Auderset, Kimberley A Pitman, Daniela Achatz, Robert Gasperini, Kaylene M Young
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0162858 (2016)
In the central nervous system (CNS) platelet derived growth factor receptor alpha (PDGFRα) is expressed exclusively by oligodendrocyte progenitor cells (OPCs), making the Pdgfrα promoter an ideal tool for directing transgene expression in this cell
Externí odkaz:
https://doaj.org/article/15dcc914951e404485ffac793f62a0ac
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0118497 (2015)
Isovaline is a non-proteinogenic amino acid that has analgesic properties. R-isovaline is a proposed agonist of the γ-aminobutyric acid type B (GABA(B)) receptor in the thalamus and peripheral tissue. Interestingly, the responses to R-isovaline diff
Externí odkaz:
https://doaj.org/article/c669bfb5977b46f8b07c477161a5d231
Autor:
Kimberley A Pitman, Kaylene M. Young, Benjamin S. Summers, Solène Ferreira, Carlie L. Cullen, Shiwei Wang
Publikováno v:
The European Journal of Neuroscience
Myelin and axon losses are associated with cognitive decline in healthy ageing but are worse in people diagnosed with tauopathy. To determine whether tauopathy is also associated with enhanced myelin plasticity, we evaluated the behaviour of OPCs in
Autor:
Mackenzie T. Clutterbuck, Viola Oorschot, Jennifer Rodger, Carlie L. Cullen, Alexander D. Tang, Loic Auderset, Ben Emery, Renee E Pepper, Renaud Jolivet, Kaylene M. Young, Kimberley A Pitman, Georg Ramm
Publikováno v:
Cell Reports, 34(3):108641. Cell Press
Central nervous system myelination increases action potential conduction velocity. However, it is unclear how myelination is coordinated to ensure the temporally precise arrival of action potentials and facilitate information processing within cortic
Autor:
Lisa Foa, Renee E Pepper, Loic Auderset, Bruce V. Taylor, Kaylene M. Young, Carlie L. Cullen, Kimberley A Pitman
Publikováno v:
Frontiers in Cell and Developmental Biology
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Low-density lipoprotein receptor-related protein 1 (LRP1) is a large, endocytic cell surface receptor that is highly expressed by oligodendrocyte progenitor cells (OPCs) and LRP1 expression is rapidly downregulated as OPCs differentiate into oligoden
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0ef508834b0f6c5410c4dc5fb05e6e7
https://doi.org/10.1101/2020.05.21.108209
https://doi.org/10.1101/2020.05.21.108209
Autor:
null Solène Ferreira, null Kimberley A Pitman, null Benjamin S Summers, null Shiwei Wang, null Kaylene M Young, null Carlie L Cullen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ff29e5792ca4e6ec8a841d1dbecb6c3
https://doi.org/10.1111/ejn.14726/v3/response1
https://doi.org/10.1111/ejn.14726/v3/response1
Autor:
Shiwei Wang, Kimberley A Pitman, Benjamin S. Summers, Carlie L. Cullen, Nicole Bye, Kaylene M. Young, Solène Ferreira
Publikováno v:
Journal of Neuroscience Research
In Alzheimer's disease, amyloid plaque formation is associated with the focal death of oligodendrocytes and soluble amyloid β impairs the survival of oligodendrocytes in vitro. However, the response of oligodendrocyte progenitor cells (OPCs) to earl
Autor:
Carlie L. Cullen, Alexander D. Tang, Viola Oorschot, Kimberley A Pitman, Jennifer Rodger, Mackenzie T. Clutterbuck, Ben Emery, Loic Auderset, Renaud Jolivet, Georg Ramm, Renee E Pepper, Kaylene M. Young
Myelination of central nervous system axons increases action potential conduction velocity and increases the speed of information transfer. However, it is unclear whether myelination optimizes action potential conduction to achieve synchronicity and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da609e1d488dd92a2f32d73526f6702c
https://doi.org/10.1101/726760
https://doi.org/10.1101/726760