Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Kimberley A, Beaumont"'
Autor:
Nikolas K. Haass, Kimberley A. Beaumont, Danae M. Sharp, Dajiang Guo, Shweta Tikoo, Wolfgang Weninger, Goldie Y. L. Lui
Publikováno v:
Pigment Cell & Melanoma Research. 33:889-894
The role of the small GTPase RAB27A as an essential melanosome trafficking regulator in melanocytes is well-accepted. A decade ago, RAB27A was identified as a tumor dependency gene that promotes melanoma cell proliferation. RAB27A has since been link
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51e901a0514fb9d185ecd81bcac0bed3
https://doi.org/10.1111/pcmr.12903
https://doi.org/10.1111/pcmr.12903
Autor:
Ethan K. Scott, Samantha J. Stehbens, Jagat Chauhan, Aaron G. Smith, Glen M. Boyle, David S. Hill, Colin R. Goding, Russell J Jurek, Sheena M. Daignault-Mill, Mitchell Fane, Gency Gunasingh, Brian Gabrielli, Nicholas Matigian, Wolfgang Weninger, Kimberley A. Beaumont, Gilles Vanwalleghem, Crystal A Tonnessen-Murray, Loredana Spoerri, Helmut Schaider, Nikolas K. Haass
Phenotypic heterogeneity of cancer cells plays a critical role in shaping treatment response. This type of heterogeneity is organized spatially with specific phenotypes, such as sharply demarcated clusters of proliferating and cell cycle-arrested cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::830ac02b4104d8d31185d81d0ffb827f
https://doi.org/10.1101/2020.06.09.141747
https://doi.org/10.1101/2020.06.09.141747
Autor:
Peter M. Ferguson, Stuart J. Gallagher, Dilini Gunatilake, Jason Madore, Kimberley A. Beaumont, James S. Wilmott, Wolfgang Weninger, Anja Heinemann, Peter Hersey, Danae M. Sharp, Jessamy Tiffen, Helen Rizos, Nikolas K. Haass
Publikováno v:
International Journal of Cancer. 142:1926-1937
Mutations in BRAF activate oncogenic MAPK signalling in almost half of cutaneous melanomas. Inhibitors of BRAF (BRAFi) and its target MEK are widely used to treat melanoma patients with BRAF mutations but unfortunately acquired resistance occurs in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b232ea533606543d20604da26280eb76
https://doi.org/10.1002/ijc.31199
https://doi.org/10.1002/ijc.31199
Autor:
Shweta Tikoo, Kimberley A. Beaumont, Dajiang Guo, Danae M. Sharp, Nikolas K. Haass, Wolfgang Weninger, Goldie Y. L. Lui
The role of the small GTPase RAB27A as an essential melanosome trafficking regulator in melanocytes is well-accepted. A decade ago, RAB27A was identified as a tumor dependency gene that promotes melanoma cell proliferation. RAB27A has since been link
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62a40557d8e8f062936f70028ca19712
Autor:
D. S. Hill, Aaron G. Smith, Jagat Chauhan, Kimberley A. Beaumont, Brian Gabrielli, Colin R. Goding, Helmut Schaider, Nikolas K. Haass, Crystal A Tonnessen-Murray, Loredana Spoerri, Gency Gunasingh, Wolfgang Weninger
Publikováno v:
Journal of Investigative Dermatology. 141:S93
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b4bff67817dd1a2b943bf304ead93159
https://doi.org/10.1016/j.jid.2021.02.563
https://doi.org/10.1016/j.jid.2021.02.563
Autor:
Aaron G. Smith, Wolfgang Weninger, Mitchell Fane, S. M. Daignault, R. J. Jurek, D. S. Hill, C. A. Tonnessen, Kimberley A. Beaumont, Loredana Spoerri, Nikolas K. Haass, Fahad W Ahmed
Publikováno v:
Experimental Dermatology. 25:E1-E54
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::491e44b50a95f8389874844b20e9e6b8
https://doi.org/10.1111/exd.12952
https://doi.org/10.1111/exd.12952
Autor:
Wolfgang Weninger, Kimberley A. Beaumont, D. S. Hill, S. M. Daignault, C. A. Tonnessen, Loredana Spoerri, Nikolas K. Haass, Brian Gabrielli
Publikováno v:
Australasian Journal of Dermatology. 58:28-30
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::246b6930d194c1ed1c0067fcd84bfe66
https://doi.org/10.1111/ajd.20_12652
https://doi.org/10.1111/ajd.20_12652
Autor:
Wolfgang Weninger, Shweta Tikoo, Kimberley A. Beaumont, Jae Sung Hwang, Rohit Jain, Dajiang Guo
Publikováno v:
Journal of Investigative Dermatology. 140:1470-1473.e3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4022b0b54531beaea317194c13296cd7
https://doi.org/10.1016/j.jid.2019.12.023
https://doi.org/10.1016/j.jid.2019.12.023
Autor:
Kimberley A. Beaumont, Russell J Jurek, Loredana Spoerri, Nikolas K. Haass, Crystal A Tonnessen-Murray, David S. Hill, Wolfgang Weninger, Gency Gunasingh
Publikováno v:
Journal of Investigative Dermatology. 140:S95
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::663090e6b28a1821ad5107a7714243bd
https://doi.org/10.1016/j.jid.2020.03.719
https://doi.org/10.1016/j.jid.2020.03.719
Autor:
Danae M. Sharp, Diego Chacon, Michelle van Geldermalsen, James S. Wilmott, Dominik Beck, Jeff Holst, Graham J. Mann, Jennifer L. Stow, Goldie Y. L. Lui, Camelia Quek, Darren L. Brown, Rain Y Q Kwan, John F. Thompson, Louise Jackett, Kimberley A. Beaumont, Wolfgang Weninger, Nikolas K. Haass, Shweta Tikoo, Dajiang Guo, Richard A. Scolyer, Jason W. H. Wong, Siew Li Lai
© 2018 UICC Despite recent advances in targeted and immune-based therapies, advanced stage melanoma remains a clinical challenge with a poor prognosis. Understanding the genes and cellular processes that drive progression and metastasis is critical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08ed3f6fdf192c349deb76f52f73c04d
https://hdl.handle.net/10453/132569
https://hdl.handle.net/10453/132569