Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Kimber L. Converso"'
Autor:
Joanne F Garbincius, Lauren E Merz, Ashley J Cuttita, Kaitlynn V Bayne, Sara Schrade, Emily A Armstead, Kimber L Converso-Baran, Steven E Whitesall, Louis G D’Alecy, Daniel E Michele
Publikováno v:
Circulation Research. 121
Duchenne muscular dystrophy (DMD) is an X-linked disease caused by mutations in dystrophin and characterized by muscle degeneration, cardiomyopathy, and impaired muscle nitric oxide (NO) production that disrupts muscle blood flow regulation and leads
Autor:
Julie R. McMullen, Tetsuo Shioi, Oleg Tarnavski, Seigo Izumo, Megan C. Sherwood, Kimber L. Converso, Warren J. Manning
Publikováno v:
Circulation. 107:1664-1670
Background— Cardiac hypertrophy, or an increase in heart size, is an important risk factor for cardiac morbidity and mortality. The mammalian target of rapamycin (mTOR) is a component of the insulin-phosphoinositide 3-kinase pathway, which is known
Autor:
Yinke Yang, Jiang-Yong Min, Yu Chen, Qingen Ke, Yong-Fu Xiao, Matthew F. Sullivan, Kimber L. Converso, James P. Morgan
Publikováno v:
The Journal of Thoracic and Cardiovascular Surgery. 125:361-369
Objective: This study was designed to investigate the feasibility of and potential functional improvement with embryonic stem cell transplantation in rats 32 weeks after myocardial infarction. Methods: Before cell transplantation, cultured embryonic
Autor:
Jiang-Yong Min, Yinke Yang, Jian-Ping Zhang, Kimber L. Converso, Matthew F. Sullivan, Yong-F.u Xiao, James P. Morgan
Publikováno v:
The Annals of Thoracic Surgery. 74:1568-1575
Background Viable cardiomyocytes after myocardial infarction (MI) are unable to repair the necrotic myocardium due to their limited capability of regeneration. The present study investigated whether intramyocardial transplantation of human mesenchyma
Autor:
Colin T. Maguire, David L. Paul, Hiroko Wakimoto, Warren J. Manning, Weei-Yuarn Huang, Hideko Kasahara, Tetsuo Shioi, Charles I. Berul, Joel A. Lawitts, Margaret Liu, Seigo Izumo, Kimber L. Converso
Publikováno v:
Journal of Clinical Investigation. 108:189-201
A DNA nonbinding mutant of the NK2 class homeoprotein Nkx2.5 dominantly inhibits cardiogenesis in Xenopus embryos, causing a small heart to develop or blocking heart formation entirely. Recently, ten heterozygous CSX/NKX2.5 homeoprotein mutations wer
Autor:
Margaret Liu, Warren J. Manning, Hiroko Wakimoto, Tomomi Ueyama, Joel A. Lawitts, Peter M. Kang, Charles I. Berul, Hideko Kasahara, Kimber L. Converso, David L. Paul, Seigo Izumo, Colin T. Maguire
Publikováno v:
Journal of molecular and cellular cardiology. 35(3)
Nkx2.5, an evolutionarily conserved homeodomain containing transcription factor, is one of the earliest cardiogenic markers. Although its expression continues through adulthood, its function in adult cardiomyocytes is not well understood. To examine
Autor:
Yinke Yang, Lixin Liu, Yong-Fu Xiao, Kimber L. Converso, Jiang-Yong Min, James P. Morgan, Qin Huang
Publikováno v:
Journal of applied physiology (Bethesda, Md. : 1985). 92(1)
Massive loss of cardiac myocytes after myocardial infarction (MI) is a common cause of heart failure. The present study was designed to investigate the improvement of cardiac function in MI rats after embryonic stem (ES) cell transplantation. MI in r