Výsledky vyhledávání

Akademický článek

Evaluation of POSSUM and P-POSSUM as predictors of mortality and morbidity in patients undergoing laparotomy at a referral hospital in Nairobi, Kenya

Autor: Kimani MM, Kiiru JN, Matu MM, Chokwe T, saidi H

Publikováno v: The Annals of African Surgery, Vol 5 (2010)

Background: The Physiological and Operative Severity Score for enUmeration of Morbidity and Mortality (POSSUM) and its Portsmouth modification (P-POSSUM) were developed for comparative audit in surgical patients. This study evaluated applicability of

Externí odkaz: https://doaj.org/article/6cd953ea82a749d7b33636922b807e3f

Zobrazit plný text záznamu

Akademický článek

Rapid screening of 2-benzylbenzimidazole nitazene analogs in suspect counterfeit tablets using Raman, SERS, DART-TD-MS, and FT-IR.

Autor: Kimani MM; Office of Regulatory Affairs, Office of Regulatory Science, Forensic Chemistry Center, US Food and Drug Administration, Cincinnati, Ohio, USA., Kern S; Office of Regulatory Affairs, Office of Regulatory Science, Forensic Chemistry Center, US Food and Drug Administration, Cincinnati, Ohio, USA., Lanzarotta A; Office of Regulatory Affairs, Office of Regulatory Science, Forensic Chemistry Center, US Food and Drug Administration, Cincinnati, Ohio, USA., Thatcher M; Office of Regulatory Affairs, Office of Regulatory Science, Forensic Chemistry Center, US Food and Drug Administration, Cincinnati, Ohio, USA., Lorenz LM; Office of Regulatory Affairs, Office of Regulatory Science, Forensic Chemistry Center, US Food and Drug Administration, Cincinnati, Ohio, USA., Smith SW; Office of Regulatory Affairs, Office of Regulatory Science, Forensic Chemistry Center, US Food and Drug Administration, Cincinnati, Ohio, USA., Collins M; Office of Regulatory Affairs, Office of Regulatory Science, Forensic Chemistry Center, US Food and Drug Administration, Cincinnati, Ohio, USA., Howe GW; Office of Regulatory Affairs, Office of Regulatory Science, Pacific Southwest Medical Products Laboratory, US Food and Drug Administration, Irvine, California, USA., Wetherby AE Jr; Office of Regulatory Affairs, Office of Regulatory Science, Winchester Engineering Analytical Center, US Food and Drug Administration, Winchester, Massachusetts, USA.

Publikováno v: Drug testing and analysis [Drug Test Anal] 2023 May; Vol. 15 (5), pp. 539-550. Date of Electronic Publication: 2023 Feb 05.

Zobrazit plný text záznamu

Akademický článek

Rapid detection of active pharmaceutical ingredients in drug products collected at an international mail facility by a satellite laboratory using a "toolkit" consisting of a handheld Raman spectrometer, portable mass spectrometer and portable FT-IR spectrometer.

Autor: Lanzarotta A; Forensic Chemistry Center, Office of Regulatory Science, Office of Regulatory Affairs, US Food & Drug Administration, Cincinnati, OH 45237, USA. Electronic address: adam.lanzarotta@fda.hhs.gov., Kern S; Forensic Chemistry Center, Office of Regulatory Science, Office of Regulatory Affairs, US Food & Drug Administration, Cincinnati, OH 45237, USA., Batson J; Forensic Chemistry Center, Office of Regulatory Science, Office of Regulatory Affairs, US Food & Drug Administration, Cincinnati, OH 45237, USA., Boyd B; Forensic Chemistry Center, Office of Regulatory Science, Office of Regulatory Affairs, US Food & Drug Administration, Cincinnati, OH 45237, USA., Kimani MM; Forensic Chemistry Center, Office of Regulatory Science, Office of Regulatory Affairs, US Food & Drug Administration, Cincinnati, OH 45237, USA., Kuo W; Forensic Chemistry Center, Office of Regulatory Science, Office of Regulatory Affairs, US Food & Drug Administration, Cincinnati, OH 45237, USA., LaGarde D; Forensic Chemistry Center, Office of Regulatory Science, Office of Regulatory Affairs, US Food & Drug Administration, Cincinnati, OH 45237, USA., Loh M; Forensic Chemistry Center, Office of Regulatory Science, Office of Regulatory Affairs, US Food & Drug Administration, Cincinnati, OH 45237, USA., Adeoshun LL; Forensic Chemistry Center, Office of Regulatory Science, Office of Regulatory Affairs, US Food & Drug Administration, Cincinnati, OH 45237, USA., Lorenz L; Forensic Chemistry Center, Office of Regulatory Science, Office of Regulatory Affairs, US Food & Drug Administration, Cincinnati, OH 45237, USA., Melendez R; Forensic Chemistry Center, Office of Regulatory Science, Office of Regulatory Affairs, US Food & Drug Administration, Cincinnati, OH 45237, USA., Morales-Garcia F; Forensic Chemistry Center, Office of Regulatory Science, Office of Regulatory Affairs, US Food & Drug Administration, Cincinnati, OH 45237, USA., Thatcher M; Forensic Chemistry Center, Office of Regulatory Science, Office of Regulatory Affairs, US Food & Drug Administration, Cincinnati, OH 45237, USA., Wetherby AE Jr; Forensic Chemistry Center, Office of Regulatory Science, Office of Regulatory Affairs, US Food & Drug Administration, Cincinnati, OH 45237, USA., Witkowski MR; Forensic Chemistry Center, Office of Regulatory Science, Office of Regulatory Affairs, US Food & Drug Administration, Cincinnati, OH 45237, USA.

Publikováno v: Journal of pharmaceutical and biomedical analysis [J Pharm Biomed Anal] 2023 Feb 05; Vol. 224, pp. 115153. Date of Electronic Publication: 2022 Nov 16.

Zobrazit plný text záznamu

Akademický článek

Screening suspect pharmaceuticals for illicit designer benzodiazepines using raman, SERS, and FT-IR prior to comprehensive analysis using LC-MS.

Autor: Kimani MM; US Food and Drug Administration, Office of Regulatory Affairs, Office of Regulatory Science, Forensic Chemistry Center, Cincinnati, OH 45237, USA. Electronic address: martin.kimani@fda.hhs.gov., Smith SW; US Food and Drug Administration, Office of Regulatory Affairs, Office of Regulatory Science, Forensic Chemistry Center, Cincinnati, OH 45237, USA., Lanzarotta A; US Food and Drug Administration, Office of Regulatory Affairs, Office of Regulatory Science, Forensic Chemistry Center, Cincinnati, OH 45237, USA., Brueggemeyer JL; US Food and Drug Administration, Office of Regulatory Affairs, Office of Regulatory Science, Forensic Chemistry Center, Cincinnati, OH 45237, USA., Batson JS; US Food and Drug Administration, Office of Regulatory Affairs, Office of Regulatory Science, Forensic Chemistry Center, Cincinnati, OH 45237, USA.

Publikováno v: Forensic science international [Forensic Sci Int] 2022 Sep; Vol. 338, pp. 111390. Date of Electronic Publication: 2022 Jul 13.

Zobrazit plný text záznamu

Akademický článek

Rapid determination of eight benzodiazepines in suspected counterfeit pharmaceuticals using surface-enhanced Raman scattering with handheld Raman spectrometers.

Autor: Kimani MM; US Food and Drug Administration, Forensic Chemistry Center, Cincinnati, OH, USA., Lanzarotta A; US Food and Drug Administration, Forensic Chemistry Center, Cincinnati, OH, USA., Batson JS; US Food and Drug Administration, Forensic Chemistry Center, Cincinnati, OH, USA.

Publikováno v: Journal of forensic sciences [J Forensic Sci] 2021 Nov; Vol. 66 (6), pp. 2167-2179. Date of Electronic Publication: 2021 Jul 27.

Zobrazit plný text záznamu

Akademický článek

Evaluation of "Toolkit" consisting of handheld and portable analytical devices for detecting active pharmaceutical ingredients in drug products collected during a simultaneous nation-wide mail blitz.

Autor: Lanzarotta A; Forensic Chemistry Center, Office of Regulatory Science, Office of Regulatory Affairs, U.S. Food & Drug Administration, Cincinnati, OH, 45237, USA. Electronic address: adam.lanzarotta@fda.hhs.gov., Kern S; Forensic Chemistry Center, Office of Regulatory Science, Office of Regulatory Affairs, U.S. Food & Drug Administration, Cincinnati, OH, 45237, USA., Batson J; Forensic Chemistry Center, Office of Regulatory Science, Office of Regulatory Affairs, U.S. Food & Drug Administration, Cincinnati, OH, 45237, USA., Falconer TM; Forensic Chemistry Center, Office of Regulatory Science, Office of Regulatory Affairs, U.S. Food & Drug Administration, Cincinnati, OH, 45237, USA., Fulcher M; Forensic Chemistry Center, Office of Regulatory Science, Office of Regulatory Affairs, U.S. Food & Drug Administration, Cincinnati, OH, 45237, USA., Gaston KW; Forensic Chemistry Center, Office of Regulatory Science, Office of Regulatory Affairs, U.S. Food & Drug Administration, Cincinnati, OH, 45237, USA., Kimani MM; Forensic Chemistry Center, Office of Regulatory Science, Office of Regulatory Affairs, U.S. Food & Drug Administration, Cincinnati, OH, 45237, USA., Lorenz L; Forensic Chemistry Center, Office of Regulatory Science, Office of Regulatory Affairs, U.S. Food & Drug Administration, Cincinnati, OH, 45237, USA., Morales-Garcia F; Forensic Chemistry Center, Office of Regulatory Science, Office of Regulatory Affairs, U.S. Food & Drug Administration, Cincinnati, OH, 45237, USA., Ranieri N; Forensic Chemistry Center, Office of Regulatory Science, Office of Regulatory Affairs, U.S. Food & Drug Administration, Cincinnati, OH, 45237, USA., Skelton D; Forensic Chemistry Center, Office of Regulatory Science, Office of Regulatory Affairs, U.S. Food & Drug Administration, Cincinnati, OH, 45237, USA., Thatcher MD; Forensic Chemistry Center, Office of Regulatory Science, Office of Regulatory Affairs, U.S. Food & Drug Administration, Cincinnati, OH, 45237, USA., Toomey VM; Forensic Chemistry Center, Office of Regulatory Science, Office of Regulatory Affairs, U.S. Food & Drug Administration, Cincinnati, OH, 45237, USA., Voelker S; Forensic Chemistry Center, Office of Regulatory Science, Office of Regulatory Affairs, U.S. Food & Drug Administration, Cincinnati, OH, 45237, USA., Witkowski MR; Forensic Chemistry Center, Office of Regulatory Science, Office of Regulatory Affairs, U.S. Food & Drug Administration, Cincinnati, OH, 45237, USA.

Publikováno v: Journal of pharmaceutical and biomedical analysis [J Pharm Biomed Anal] 2021 Sep 05; Vol. 203, pp. 114183. Date of Electronic Publication: 2021 Jun 02.

Zobrazit plný text záznamu

Akademický článek

Trace level detection of select opioids (fentanyl, hydrocodone, oxycodone, and tramadol) in suspect pharmaceutical tablets using surface-enhanced Raman scattering (SERS) with handheld devices.

Publikováno v: Journal of forensic sciences [J Forensic Sci] 2021 Mar; Vol. 66 (2), pp. 491-504. Date of Electronic Publication: 2020 Nov 02.

Zobrazit plný text záznamu

Akademický článek

Evaluation of Suspected Counterfeit Pharmaceutical Tablets Declared to Contain Controlled Substances Using Handheld Raman Spectrometers.

Autor: Lanzarotta A; Forensic Chemistry Center, Office of Regulatory Science, Office of Regulatory Affairs, U.S. Food & Drug Administration, Cincinnati, OH, 45237., Kimani MM; Forensic Chemistry Center, Office of Regulatory Science, Office of Regulatory Affairs, U.S. Food & Drug Administration, Cincinnati, OH, 45237., Thatcher MD; Forensic Chemistry Center, Office of Regulatory Science, Office of Regulatory Affairs, U.S. Food & Drug Administration, Cincinnati, OH, 45237., Lynch J; Forensic Chemistry Center, Office of Regulatory Science, Office of Regulatory Affairs, U.S. Food & Drug Administration, Cincinnati, OH, 45237., Fulcher M; Forensic Chemistry Center, Office of Regulatory Science, Office of Regulatory Affairs, U.S. Food & Drug Administration, Cincinnati, OH, 45237., Witkowski MR; Forensic Chemistry Center, Office of Regulatory Science, Office of Regulatory Affairs, U.S. Food & Drug Administration, Cincinnati, OH, 45237., Batson JS; Forensic Chemistry Center, Office of Regulatory Science, Office of Regulatory Affairs, U.S. Food & Drug Administration, Cincinnati, OH, 45237.

Publikováno v: Journal of forensic sciences [J Forensic Sci] 2020 Jul; Vol. 65 (4), pp. 1274-1279. Date of Electronic Publication: 2020 Jan 27.

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání