Molecular screening for Plasmodium falciparum resistance markers for artemisinins in Mbita, Kenya

Autor: Wangai, LN, Geoffrey, M, Omar, S, Magoma, G, Kimani, FT, Mwangi, JM, Burugu, MW, Maina, N

Publikováno v: African Journal of Clinical and Experimental Microbiology; Vol 12, No 3 (2011)

Artemisinins-based combination therapies (ACTs) are being recommended against uncomplicated malaria in endemic areas of Africa. However, in these areas data on their long term usefulness is limited. It has been demonstrated that ACTs resistance may b

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https://www.ajol.info/index.php/ajcem/article/view/66909

Antimalarial activity assay of artesunate-3-chloro-4(4-chlorophenoxy) aniline in vitro and in mice models.

Autor: Waithera MW; Department of Mechanical Engineering, Graduate School of Science and Engineering, Chiba University, 1-33, Inage-Ku, Chiba-Shi, Chiba, 263-8522, Japan.; Department of Biochemistry, Jomo Kenyatta University of Agriculture and Technology, P.O Box 62000-00200, Nairobi, Kenya., Sifuna MW; Department of Mechanical Engineering, Graduate School of Science and Engineering, Chiba University, 1-33, Inage-Ku, Chiba-Shi, Chiba, 263-8522, Japan. sifuna@chiba-u.jp., Kariuki DW; Department of Biochemistry, Jomo Kenyatta University of Agriculture and Technology, P.O Box 62000-00200, Nairobi, Kenya., Kinyua JK; Department of Biochemistry, Jomo Kenyatta University of Agriculture and Technology, P.O Box 62000-00200, Nairobi, Kenya., Kimani FT; Centre for Biotechnology Research and Development, Kenya Medical Research Institute, P.O Box, Nairobi, 54840-00200, Kenya., Ng'ang'a JK; Department of Biochemistry, Jomo Kenyatta University of Agriculture and Technology, P.O Box 62000-00200, Nairobi, Kenya., Takei M; Department of Mechanical Engineering, Graduate School of Science and Engineering, Chiba University, 1-33, Inage-Ku, Chiba-Shi, Chiba, 263-8522, Japan.

Publikováno v: Parasitology research [Parasitol Res] 2023 Apr; Vol. 122 (4), pp. 979-988. Date of Electronic Publication: 2023 Mar 02.

Efficacy of artemisinin-lumefantrine for treatment of uncomplicated malaria after more than a decade of its use in Kenya.

Autor: Kishoyian G; Department of Medical Laboratory Sciences, Kenya Medical Training College, P.O. Box2268-40100, Kisumu, Kenya., Njagi ENM; Department of Biochemistry and Biotechnology, Kenyatta University, P.O.BOX 43844-00100, Nairobi, Kenya., Orinda GO; Department of Biochemistry and Biotechnology, Kenyatta University, P.O.BOX 43844-00100, Nairobi, Kenya., Kimani FT; Centre for Biotechnology Research and Development, Kenya Medical Research Institute, P.O. Box 54840-00200, Nairobi, Kenya., Thiongo K; Centre for Biotechnology Research and Development, Kenya Medical Research Institute, P.O. Box 54840-00200, Nairobi, Kenya., Matoke-Muhia D; Centre for Biotechnology Research and Development, Kenya Medical Research Institute, P.O. Box 54840-00200, Nairobi, Kenya.

Publikováno v: Epidemiology and infection [Epidemiol Infect] 2021 Jan 05; Vol. 149, pp. e27. Date of Electronic Publication: 2021 Jan 05.

Prevalence of mutations in Plasmodium falciparum genes associated with resistance to different antimalarial drugs in Nyando, Kisumu County in Kenya.

Autor: Musyoka KB; Department of Biochemistry, Jomo Kenyatta University of Agriculture and Technology, Nairobi, Kenya; Centre for Biotechnology Research and Development, Kenya Medical Research Institute, Nairobi, Kenya. Electronic address: musyoka618@gmail.com., Kiiru JN; Centre for Microbiology Research, Kenya Medical Research Institute, Nairobi, Kenya., Aluvaala E; Centre for Biotechnology Research and Development, Kenya Medical Research Institute, Nairobi, Kenya., Omondi P; Department of Biochemistry, Microbiology, and Biotechnology, Kenyatta University, Nairobi, Kenya., Chege WK; Centre for Biotechnology Research and Development, Kenya Medical Research Institute, Nairobi, Kenya., Judah T; Centre for Microbiology Research, Kenya Medical Research Institute, Nairobi, Kenya., Kiboi D; Department of Biochemistry, Jomo Kenyatta University of Agriculture and Technology, Nairobi, Kenya., Nganga JK; Department of Biochemistry, Jomo Kenyatta University of Agriculture and Technology, Nairobi, Kenya., Kimani FT; Centre for Biotechnology Research and Development, Kenya Medical Research Institute, Nairobi, Kenya.

Publikováno v: Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases [Infect Genet Evol] 2020 Mar; Vol. 78, pp. 104121. Date of Electronic Publication: 2019 Nov 19.

Efficacy and safety evaluation of a novel trioxaquine in the management of cerebral malaria in a mouse model.

Autor: Odhiambo OC; Department of Biochemistry, Jomo Kenyatta University of Agriculture and Technology, P.O. Box 62000, Nairobi, Kenya., Wamakima HN; Department of Pharmaceutical Sciences, Mount Kenya University, P.O. Box 342-01000, Thika, Kenya., Magoma GN; Department of Biochemistry, Jomo Kenyatta University of Agriculture and Technology, P.O. Box 62000, Nairobi, Kenya., Kirira PG; Department of Physical Sciences, Mount Kenya University, P.O. Box 342-01000, Thika, Kenya., Malala BJ; Department of Biological Sciences, Mount Kenya University, P.O. Box 342-01000, Thika, Kenya., Kimani FT; Centre for Biotechnology Research and Development, Kenya Medical Research Institute (KEMRI), P.O. Box 54840, Nairobi, Kenya., Muregi FW; Department of Biological Sciences, Mount Kenya University, P.O. Box 342-01000, Thika, Kenya. fmuregi@mku.ac.ke.

Publikováno v: Malaria journal [Malar J] 2017 Jul 03; Vol. 16 (1), pp. 268. Date of Electronic Publication: 2017 Jul 03.