Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Kim-Dung Huynh"'
Autor:
Christian Vogler, Klara Spalek, Amanda Aerni, Philippe Demougin, Ariane Müller, Kim-Dung Huynh, Andreas Papassotiropoul, Dominique J F De Quervain
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 3 (2009)
Cytoplasmic polyadenylation element-binding (CPEB) proteins are crucial for synaptic plasticity and memory in model organisms. A highly conserved, mammalian-specific short intronic sequence within CPEB3 has been identified as a ribozyme with self-cle
Externí odkaz:
https://doaj.org/article/061565c227134b149f792232ba808619
Autor:
Peter Boesiger, Dominique J.-F. de Quervain, Klaus Scheffler, Amanda Aerni, Christian Vogler, Sandra Ackermann, Kostic, Andreas Papassotiropoulos, Edveena Hanser, Kim-Dung Huynh, Roger Luechinger, Markus Klarhöfer, Philippe Demougin, Leo Gschwind, Elka Stefanova, Klara Spalek, Ivana Novakovic, Angela Heck, Björn Rasch
Publikováno v:
Molecular Psychiatry; Vol 18
Molecular Psychiatry
Molecular psychiatry
Molecular Psychiatry
Molecular psychiatry
Unbiased genome wide screens combined with imaging data on brain function may identify novel molecular pathways related to human cognition. Here we performed a dense genome wide screen to identify episodic memory related gene variants. A genomic locu
Autor:
Dominique J.-F. de Quervain, Kim-Dung Huynh, Andreas Papassotiropoulos, J. C. Sigmund, Christian Vogler
Publikováno v:
Biological Psychology. 79:239-242
A functional polymorphism (His452Tyr) in the gene encoding the serotonin 2A receptor (HTR2A) has been previously associated with human episodic memory performance and with differences in brain volume in memory-related brain regions. Here we present d
Autor:
David Osborne, Andreas Papassotiropoulos, Jason J. Corneveaux, Andreas Buchmann, Katharina Henke, Jürgen Hänggi, David Craig, Christian R.A. Mondadori, Kim Dung Huynh, Eric M. Reiman, Daniel Coluccia, Richard J. Caselli, Dietrich A. Stephan, M. Axel Wollmer, Amanda Aerni, Dominique J.-F. de Quervain, Matthew J. Huentelman, John V. Pearson, Frédéric J. Hoerndli, Fabienne Brunner
Publikováno v:
Science. 314:475-478
Human memory is a polygenic trait. We performed a genome-wide screen to identify memory-related gene variants. A genomic locus encoding the brain protein KIBRA was significantly associated with memory performance in three independent, cognitively nor
Autor:
Christiane Gerhards, Andrea Pfeifer, Amanda Aerni, Paolo Paganetti, Philippe Demougin, Kim-Dung Huynh, Bianca Auschra, Leo Gschwind, Frank Jessen, Klara Spalek, Nathalie Schicktanz, Sandra Ackermann, Edveena Hanser, Andreas Papassotiropoulos, Verena Ertl, Christian Vogler, Thomas Elbert, Andreas Muhs, Dominique J.-F. de Quervain, Iris-Tatjana Kolassa, Angela Heck, Eva Mumme, Annette Milnik
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
In the last decade there has been an exponential increase in knowledge about the genetic basis of complex human traits, including neuropsychiatric disorders. It is not clear, however, to what extent this knowledge can be used as a starting point for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0564f0325eda957dac6836bf5080dc8c
Autor:
Roger M. Nitsch, Magdalini Tsolaki, Kim-Dung Huynh, Christoph Hock, Andreas U. Monsch, Dimitra Molyva, M. Axel Wollmer, Jay Tracy, Dietmar Rudolf Thal, Andreas Papassotiropoulos, Hannes B. Staehelin
Publikováno v:
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. :21-23
A 30 cM broad genomic region on the long arm of chromosome 10 at 80 cM shows significant and consistent linkage with AD and with plasma concentration of the beta-amyloid peptide 1-42 (Abeta42). The PLAU gene, which is involved in the production and d
Autor:
Dominique J.-F. de Quervain, Iris-Tatjana Kolassa, Edveena Hanser, Christoph Stippich, Peter Boesiger, Markus Klarhöfer, Angela Heck, Attila Stetak, Verena Ertl, N.O. Hadziselimovic, Roger Luechinger, Amanda Aerni, Philippe Demougin, Klaus Scheffler, Vanja Vukojevic, Petra Hieber, Thomas Elbert, Björn Rasch, Kim-Dung Huynh, Leo Gschwind, Klara Spalek, Andreas Papassotiropoulos, Christian Vogler, Sandra Ackermann
Publikováno v:
Proceedings of the National Academy of Sciences
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences; Vol 109
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences; Vol 109
Strong memory of a traumatic event is thought to contribute to the development and symptoms of posttraumatic stress disorder (PTSD). Therefore, a genetic predisposition to build strong memories could lead to increased risk for PTSD after a traumatic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ada65d9c693565e6d90e09aa0eb5b44d
Autor:
Elisabeth Kapaki, Dimitra Molyva, Lena Kilander, Fabienne Brunner, Christoph Hock, Kim-Dung Huynh, Anna Glaser, Marie Hedlund, Maria Barcikowska, Roger M. Nitsch, Kristel Sleegers, Magdalini Tsolaki, Cezary Zekanowski, RoseMarie Brundin, Lars Lannfelt, Aleksandra Maruszak, George P. Paraskevas, Vilmantas Giedraitis, Makrina Daniilidou, Nathalie Brouwers, Andreas Papassotiropoulos, Peter Paul De Deyn, M. Axel Wollmer, Sebastiaan Engelborghs, Jacek Kuznicki, Martin Ingelsson, Christine Van Broeckhoven, Dietmar Rudolf Thal
Publikováno v:
Neurogenetics
Alzheimer's disease (AD) is a genetically complex disorder, and several genes related to cholesterol metabolism have been reported to contribute to AD risk. To identify further AD susceptibility genes, we have screened genes that map to chromosomal r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f367318d782b7fa135125533d8928e6e
https://www.zora.uzh.ch/id/eprint/49421/
https://www.zora.uzh.ch/id/eprint/49421/
Autor:
Luigi M.E. Grimaldi, M. Axel Wollmer, Thomas Hegi, Sibylle Wolleb, Elisabeth Kapaki, Philippe Amouyel, Andreas Papassotiropoulos, Johannes Streffer, Alessia Maddalena, Uwe Konietzko, John Hardy, Jean-Charles Lambert, Heinz Von Der Kammer, Hans H. Jung, Kim-Dung Huynh, Christoph Hock, Heiko Braak, Thomas Pasch, Dieter Lütjohann, Roger M. Nitsch, Magdalini Tsolaki, Dietmar Rudolf Thal, Rivka Ravid, Brigitte Schneider, Fabienne Wavrant-De Vrièze, Evgeny I. Rogaev
Alzheimer’s disease (AD) is the most common cause of dementia. It is characterized by β-amyloid (Aβ) plaques, neurofibrillary tangles and the degeneration of specifically vulnerable brain neurons. We observed high expression of the cholesterol 25
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c44903f6c8c895c063bdc08fc2301d1
https://www.zora.uzh.ch/id/eprint/49534/
https://www.zora.uzh.ch/id/eprint/49534/
Autor:
Dietmar Rudolf Thal, Magdalini Tsolaki, Fabienne Brunner, Kim-Dung Huynh, Christoph Hock, Roger M. Nitsch, Andreas Papassotiropoulos, M A Wollmer
Publikováno v:
Neurobiology of Aging. 25:S488