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Autor:
Peter Charles, Michael J. Elliott, Diana Davis, Alison Potter, Joachim R. Kalden, Christian Antoni, Ferdinand C. Breedveld, Josef S. Smolen, Gabriele Eberl, Kim deWoody, Marc Feldmann, Ravinder N. Maini
Publikováno v:
The Journal of Immunology. 163:1521-1528
Treatment with a chimeric mAb to TNF-α has been shown to suppress inflammation and improve patient well-being in rheumatoid arthritis (RA), but the mechanisms of action of such treatment have not been fully explored. Here we show that in vivo admini