Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Kim Z Travis"'
Autor:
Richard Jay Smeyne, Charles B Breckenridge, Melissa Beck, Yun Jiao, Mark T Butt, Jeffrey C Wolf, Dan Zadory, Daniel J Minnema, Nicholas C Sturgess, Kim Z Travis, Andrew R Cook, Lewis L Smith, Philip A Botham
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0164094 (2016)
The neurotoxicity of paraquat dichloride (PQ) was assessed in two inbred strains of 9- or 16-week old male C57BL/6 mice housed in two different laboratories and compared to the effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). PQ was ad
Externí odkaz:
https://doaj.org/article/f994ce1641f14c128b4b02f13f570ad2
Autor:
Jane Botham, Richard W. Lewis, Kim Z. Travis, Audrey Baze, Lysiane Richert, Elizabeth Codrea, Giovanna Semino Beninel, Jean-Christophe Garcin, Christian Strupp
Publikováno v:
Archives of Toxicology. 97:991-999
The mode of action (MoA) of the 4-hydroxyphenylpyruvate dioxygenase (HPPD) inhibitor herbicides in mammals is well described and is generally accepted to be due to a build-up of excess systemic tyrosine which is associated with the range of adverse e
Publikováno v:
AQUATIC MESOCOSM STUDIES in ECOLOGICAL RISK ASSESSMENT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6de33c833d8559f0630920a3446dc644
https://doi.org/10.1201/9781003070016-18
https://doi.org/10.1201/9781003070016-18
Autor:
Paul M. Hinderliter, Philip A. Botham, Daniel J. Minnema, Harvey J. Clewell, Kim Z. Travis, Andrew R. Cook, Jerry L. Campbell, Alexander Stevens, Douglas C. Wolf
Publikováno v:
Toxicology and applied pharmacology. 417
By extending our Paraquat (PQ) work to include primates we have implemented a modelling and simulation strategy that has enabled PQ pharmacokinetic data to be integrated into a single physiologically based pharmacokinetic (PBPK) model that enables mo
Publikováno v:
Environmental Science and Pollution Research International
Exposure to several specific pesticides has led to an increase of Parkinson's disease (PD) risk. However, it is difficult to quantify the PD population risk related to certain pesticides in regions where environmental exposure data are scarce. Furthe
Autor:
Kim Z. Travis, Jerry L. Campbell, Alexander Stevens, Philip A. Botham, Daniel J. Minnema, Douglas C. Wolf, Paul M. Hinderliter, Andrew R. Cook, Harvey J. Clewell, Melvin E. Andersen
Publikováno v:
Toxicology and Applied Pharmacology. 417:115462
Paraquat dichloride (PQ) is a non-selective herbicide which has been the subject of numerous toxicology studies over more than 50 years. This paper describes the development of a physiologically-based pharmacokinetic (PBPK) model of PQ kinetics for t
Publikováno v:
Freshwater Field Tests for Hazard Assessment of Chemicals ISBN: 9780203755488
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c6603346b91e20d947f69dc82efef85
https://doi.org/10.1201/9780203755488-6
https://doi.org/10.1201/9780203755488-6
Autor:
Philip A. Botham, Merrill O. Tisdel, James M. Mathews, Andrew R. Cook, Kim Z. Travis, Jeffrey C. Wolf, Dan Zadory, Charles B. Breckenridge, Daniel J. Minnema, Mark T. Butt, Melissa J. Beck, Smith Ll, Nicholas C. Sturgess
Publikováno v:
NeuroToxicology. 37:1-14
The pharmacokinetics and neurotoxicity of paraquat dichloride (PQ) were assessed following once weekly administration to C57BL/6J male mice by intraperitoneal injection for 1, 2 or 3 weeks at doses of 10, 15 or 25 mg/kg/week. Approximately 0.3% of th
Autor:
Paul R. Trundle, Anna Palczewska, Longzhi Yang, Kim Z. Travis, Daniel Neagu, Mick Ridley, Xin Fu
Publikováno v:
International Journal of Information Management. 33:567-582
Efficient management of toxicity information as an enterprise asset is increasingly important for the chemical, pharmaceutical, cosmetics and food industries. Many organisations focus on better information organisation and reuse, in an attempt to red
Autor:
Nicholas C. Sturgess, Mark T. Butt, Philip A. Botham, Kim Z. Travis, Charles B. Breckenridge, Lewis L. Smith, Yun Jiao, Dan Zadory, Richard J. Smeyne, Jeffrey C. Wolf, Andrew R. Cook, Melissa J. Beck, Daniel J. Minnema
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0164094 (2016)
PLoS ONE
PLoS ONE
The neurotoxicity of paraquat dichloride (PQ) was assessed in two inbred strains of 9- or 16-week old male C57BL/6 mice housed in two different laboratories and compared to the effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). PQ was ad