Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Kim Williamson"'
Autor:
Regina Joice, Vagheesh Narasimhan, Jacqui Montgomery, Amar Bir Sidhu, Keunyoung Oh, Evan Meyer, Willythssa Pierre-Louis, Karl Seydel, Danny Milner, Kim Williamson, Roger Wiegand, Daouda Ndiaye, Johanna Daily, Dyann Wirth, Terrie Taylor, Curtis Huttenhower, Matthias Marti
Publikováno v:
PLoS Computational Biology, Vol 9, Iss 12, p e1003392 (2013)
In the current era of malaria eradication, reducing transmission is critical. Assessment of transmissibility requires tools that can accurately identify the various developmental stages of the malaria parasite, particularly those required for transmi
Externí odkaz:
https://doaj.org/article/6a5f3a6117014388998c94323d7c11f1
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
'Scientific Reports ', vol: 11, pages: 18693-1-18693-14 (2021)
Scientific Reports
'Scientific Reports ', vol: 11, pages: 18693-1-18693-14 (2021)
Scientific Reports
DNA ligases, the enzymes responsible for joining breaks in the phosphodiester backbone of DNA during replication and repair, vary considerably in size and structure. The smallest members of this enzyme class carry out their functions with pared-down
Publikováno v:
Nucleic Acids Research
DNA ligases are diverse enzymes with essential functions in replication and repair of DNA; here we review recent advances in their structure and distribution and discuss how this contributes to understanding their biological roles and technological p
DNA ligases, essential enzymes which re-join the backbone of DNA come in two structurally-distinct isoforms, NAD-dependent and ATP-dependent, which differ in cofactor usage. The present view is that all bacteria exclusively use NAD-dependent DNA liga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67c57109b6a6039c98be90a8139fa6eb
Autor:
Luke J Stevenson, Adele Kim Williamson, Katherine J. Robins, Wayne M. Patrick, Janine K Sharma, David F. Ackerley
DNA ligases have numerous applications in molecular biology and biotechnology. However, many of these applications require the ligation of blunt-ended DNA termini, which is an inefficient activity for existing commercial ligases. To address this limi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::084cdc777e8fe39c5ee928d71af57488
https://doi.org/10.1016/bs.mie.2020.04.061
https://doi.org/10.1016/bs.mie.2020.04.061
Autor:
Hasan Arsin, Pål Puntervoll, Øivind Larsen, Adele Kim Williamson, Antonio García-Moyano, Gro Elin Kjæreng Bjerga, Ingar Leiros
Publikováno v:
Proteins: Structure, Function, and Bioinformatics. 86:965-977
Intracellular subtilisin proteases (ISPs) have important roles in protein processing during the stationary phase in bacteria. Their unregulated protein degrading activity may have adverse effects inside a cell, but little is known about their regulat
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
'Scientific Reports ', vol: 7, pages: 17278-1-17278-10 (2017)
Scientific Reports
'Scientific Reports ', vol: 7, pages: 17278-1-17278-10 (2017)
Scientific Reports
Source at http://dx.doi.org/10.1038/s41598-017-17677-4 . The family 15 carbohydrate esterase (CE15) MZ0003, which derives from a marine Arctic metagenome, has a broader substrate scope than other members of this family. Here we report the crystal str
This is a post-peer-review, pre-copyedit version of an article published in Extremophiles. The final authenticated version is available online at: https://doi.org/10.1007/s00792-019-01082-y. DNA ligases operating at low temperatures have potential ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a49c9900a9dcbc739a1e379f0160615
https://hdl.handle.net/10037/18024
https://hdl.handle.net/10037/18024
Publikováno v:
Nucleic Acids Research
'Nucleic Acids Research ', vol: 47, pages: 7147-7162 (2019)
'Nucleic Acids Research ', vol: 47, pages: 7147-7162 (2019)
Source at https://doi.org/10.1093/nar/gkz596. DNA ligases join adjacent 5′ phosphate (5′P) and 3′ hydroxyl (3′OH) termini of double-stranded DNA via a three-step mechanism requiring a nucleotide cofactor and divalent metal ion. Although consi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::062d73bb9440d0cdd832bed39a697233
https://hdl.handle.net/10037/16058
https://hdl.handle.net/10037/16058
Publikováno v:
Molecular Microbiology. 99:274-290
Prior to the discovery of a minimal ATP-dependent DNA ligase in Haemophilus influenzae, bacteria were thought to only possess a NAD-dependent ligase, which was involved in sealing of Okazaki fragments. We now know that a diverse range of bacterial sp