Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Kim Watt"'
Publikováno v:
Journal of Lipid Research, Vol 51, Iss 6, Pp 1407-1415 (2010)
HDL cholesterol levels are decreased in Crohn's disease, a tumor necrosis factor-α (TNF-α)–driven chronic inflammatory condition involving the gastrointestinal tract. ATP-binding cassette transporter A1 (ABCA1), one of several liver X receptor (L
Externí odkaz:
https://doaj.org/article/d1c0417a65164beaa366b462351beb53
Publikováno v:
Journal of Lipid Research, Vol 49, Iss 12, Pp 2605-2619 (2008)
The origins of cholesterol utilized by intestinal ABCA1 were investigated in the human intestinal cell line Caco-2. Influx of apical membrane cholesterol increases ABCA1 mRNA and mass, resulting in enhanced efflux of HDL-cholesterol. Luminal (micella
Externí odkaz:
https://doaj.org/article/577cb3d7fc2246b18102c557992cedf0
Publikováno v:
Journal of Lipid Research, Vol 48, Iss 8, Pp 1735-1745 (2007)
Niemann-Pick C1-like 1 protein (NPC1L1) is the putative intestinal sterol transporter and the molecular target of ezetimibe, a potent inhibitor of cholesterol absorption. To address the role of NPC1L1 in cholesterol trafficking in intestine, the regu
Externí odkaz:
https://doaj.org/article/d6d0fa1ec477464eabedd1b730f5bbe8
Publikováno v:
Journal of Lipid Research, Vol 49, Iss 12, Pp 2605-2619 (2008)
The origins of cholesterol utilized by intestinal ABCA1 were investigated in the human intestinal cell line Caco-2. Influx of apical membrane cholesterol increases ABCA1 mRNA and mass, resulting in enhanced efflux of HDL-cholesterol. Luminal (micella
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b29d8dfb633ff0ad972afe6337e02843
http://www.sciencedirect.com/science/article/pii/S0022227520345910
http://www.sciencedirect.com/science/article/pii/S0022227520345910
Publikováno v:
Journal of Lipid Research, Vol 48, Iss 8, Pp 1735-1745 (2007)
Niemann-Pick C1-like 1 protein (NPC1L1) is the putative intestinal sterol transporter and the molecular target of ezetimibe, a potent inhibitor of cholesterol absorption. To address the role of NPC1L1 in cholesterol trafficking in intestine, the regu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b58674f095bf2d28eaa3a267203c5e1b
http://www.sciencedirect.com/science/article/pii/S002222752042509X
http://www.sciencedirect.com/science/article/pii/S002222752042509X
Autor:
Julia L. MacIsaac, Sarah M. Neumann, Michael S. Kobor, Kim Watt, Eldon Emberly, Meaghan J. Jones, Naznin Virji-Babul, Lisa M. McEwen, Max S. Cynader, Pau Farré
Publikováno v:
BMC Medical Genomics
Background The presence of an extra whole or part of chromosome 21 in people with Down syndrome (DS) is associated with multiple neurological changes, including pathological aging that often meets the criteria for Alzheimer’s Disease (AD). In addit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58725cb1f4f46c4436dcd020441eda28
Autor:
Sue Cooper, Sarah Lewis, James G Thornton, Neil Marlow, Kim Watts, John Britton, Matthew J Grainge, Jaspal Taggar, Holly Essex, Steve Parrott, Anne Dickinson, Rachel Whitemore, Tim Coleman, for the Smoking, Nicotine And Pregnancy (SNAP) Trial Team
Publikováno v:
Health Technology Assessment, Vol 18, Iss 54 (2014)
Background: Smoking during pregnancy causes many adverse pregnancy and birth outcomes. Nicotine replacement therapy (NRT) is effective for cessation outside pregnancy but efficacy and safety in pregnancy are unknown. We hypothesised that NRT would in
Externí odkaz:
https://doaj.org/article/ccdb9dd5d62d4590900bf32cb5439da4
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