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pro vyhledávání: '"Kim Verdries"'
Autor:
Robert B. Nelson, Susan E. Drozda, Steve Faraci, Kim Verdries, Pat Seymour, Robert A. Volkmann, Weimin Qian, and Anabella Villalobos, Dane R. Liston, W. Frost White, Charles E. Nolan, John A. Lowe, Michael Majchrzak, Deane M. Nason, Karen M. Ward
Publikováno v:
Journal of Medicinal Chemistry. 47:1575-1586
The synthesis and structure-activity relationships of a series of 6-phenyl-2-aminopyridines that potently and selectively inhibit the neuronal isoform of nitric oxide synthase (nNOS) are described. Compound 14bi from this series exhibits potent in vi