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pro vyhledávání: '"Kim Tipton"'
Autor:
Teodora Losic, Mary Do, Kim Tipton, Satyajit Sujit Kumar Mitra, Tony W. Liang, Jeffrey Kang, Sanjeev Satyal, Vasu Jammalamadaka, Greg Tuffy, William E. Haskins, William Monteith, Adriana Gamboa Lopez, Scott Savage, Melissa S. Jurica
Publikováno v:
Cancer Research. 81:1832-1832
Background: Thailanstatins are naturally occurring anti-proliferative compounds that target spliceosomes and modulate pre-mRNA splicing. Alterations in splicing machinery and mRNA splicing is common in cancer and represents a potential susceptibility
Autor:
Luc Desnoyers, Yuanhui Huang, Shouchun Liu, Annie Yang Weaver, Shweta Singh, Linnea Diep, Kim Tipton, Jonathan Alexander Terrett, Clayton White, Jennifer Richardson, Amy DuPage, W. Michael Kavanaugh, Michael Krimm, Jason Gary Sagert
Publikováno v:
Cancer Research. 76:2975-2975
The targets of Antibody Drug Conjugates (ADCs) have typically been selected by identifying transmembrane antigens that are highly expressed in tumors but are low or absent in normal tissues. The number of potential ADC targets meeting these requireme