Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Kim T. Arndt"'
Autor:
Hans-Peter Gerber, Kim T. Arndt, Christopher J. O'Donnell, Andreas Maderna, Edmund Graziani, Judy Lucas, Mike Cinque, Kenny Sung Kyoo Kim, Kiran Khandke, Manoj B. Charati, William Hu, My-Hanh Lam, Sylvia Musto, Maximillian T. Follettie, Veronica Diesl, Fang Wang, Eugene Melamud, Jeremy S. Myers, Guixian Jin, Matthew Sung, Xingzhi Tan, Frank Loganzo
Supplementary Figures S1 to S11. Supplementary Figure S1: Schematic illustration of the approach used to create trastuzumab-maytansinoid ADC resistant cell lines. Supplementary Figure S2: Structures of payloads and ADCs. Supplementary Figure S3: 361-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d79603999d612f532f7eea3bb1f02469
https://doi.org/10.1158/1535-7163.22500637.v1
https://doi.org/10.1158/1535-7163.22500637.v1
Autor:
Hans-Peter Gerber, Kim T. Arndt, Christopher J. O'Donnell, Andreas Maderna, Edmund Graziani, Judy Lucas, Mike Cinque, Kenny Sung Kyoo Kim, Kiran Khandke, Manoj B. Charati, William Hu, My-Hanh Lam, Sylvia Musto, Maximillian T. Follettie, Veronica Diesl, Fang Wang, Eugene Melamud, Jeremy S. Myers, Guixian Jin, Matthew Sung, Xingzhi Tan, Frank Loganzo
Supplementary Methods, Table S1 S2, and Figure Legends. Supplementary Table S1: Properties of cell lines made resistant to TM-conjugate. Supplementary Table S2: Relative resistance of selected free payloads and Cys-capped-released species in H69 (no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::030c02d31cd9136288d63c1ed31908a5
https://doi.org/10.1158/1535-7163.22500634.v1
https://doi.org/10.1158/1535-7163.22500634.v1
Autor:
Shunqiang Li, Donald P. McDonnell, John D. Norris, Jin-Ping Lai, Robert Crowder, Jieya Shao, Elizabeth Griffin, Tina Primeau, Kim T. Arndt, Stephen G. Dann, Todd VanArsdale, Koleen Eisele, Holly M. Alley, Matthew J. Ellis, Suzanne E. Wardell
Supplemental figure 3: SERDs and palbociclib inhibit breast cancer cell proliferation by independent mechanisms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::913466b83847b02760d8832503645b8d
https://doi.org/10.1158/1078-0432.22454691.v1
https://doi.org/10.1158/1078-0432.22454691.v1
Autor:
Shunqiang Li, Donald P. McDonnell, John D. Norris, Jin-Ping Lai, Robert Crowder, Jieya Shao, Elizabeth Griffin, Tina Primeau, Kim T. Arndt, Stephen G. Dann, Todd VanArsdale, Koleen Eisele, Holly M. Alley, Matthew J. Ellis, Suzanne E. Wardell
Supplemental figure 4: Evaluation of pharmacodynamics endpoints confirms on target activity of SERDs and palbociclib, resulting in sustained inhibition of tumors receiving both treatments
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ee29c5e6c07b5a865bf126f1bef796e
https://doi.org/10.1158/1078-0432.22454688
https://doi.org/10.1158/1078-0432.22454688
Autor:
Shunqiang Li, Donald P. McDonnell, John D. Norris, Jin-Ping Lai, Robert Crowder, Jieya Shao, Elizabeth Griffin, Tina Primeau, Kim T. Arndt, Stephen G. Dann, Todd VanArsdale, Koleen Eisele, Holly M. Alley, Matthew J. Ellis, Suzanne E. Wardell
Supplemental figure 1: SERDs and SERMs differ in their ability to inhibit ER-dependent stimulation of breast cancer cell proliferation by growth factors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45421649f6c61cc430618d3b84ec6afd
https://doi.org/10.1158/1078-0432.22454700
https://doi.org/10.1158/1078-0432.22454700
Autor:
Shunqiang Li, Donald P. McDonnell, John D. Norris, Jin-Ping Lai, Robert Crowder, Jieya Shao, Elizabeth Griffin, Tina Primeau, Kim T. Arndt, Stephen G. Dann, Todd VanArsdale, Koleen Eisele, Holly M. Alley, Matthew J. Ellis, Suzanne E. Wardell
Supplemental figure 2: SERDs inhibit the constitutive activity of the clinically relevant Y537N,D538G ESR1 double mutant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53e5398bfcdac49fc14ce14291926781
https://doi.org/10.1158/1078-0432.22454697.v1
https://doi.org/10.1158/1078-0432.22454697.v1
Autor:
Shunqiang Li, Donald P. McDonnell, John D. Norris, Jin-Ping Lai, Robert Crowder, Jieya Shao, Elizabeth Griffin, Tina Primeau, Kim T. Arndt, Stephen G. Dann, Todd VanArsdale, Koleen Eisele, Holly M. Alley, Matthew J. Ellis, Suzanne E. Wardell
Supplemental figure 5: IHC analysis of treated PDX tumors indicated on-target activity of bazedoxifene and palbociclib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::741a8d0744eed5814f3385c071daffe5
https://doi.org/10.1158/1078-0432.22454685
https://doi.org/10.1158/1078-0432.22454685
Publikováno v:
Molecular and Cellular Biology. 11:2133-2148