Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Kim S Rutgers"'
Autor:
Rob J A Nabuurs, Kim S Rutgers, Mick M Welling, Athanasios Metaxas, Maaike E de Backer, Maarten Rotman, Brian J Bacskai, Mark A van Buchem, Silvère M van der Maarel, Louise van der Weerd
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e38284 (2012)
This study investigated the in vivo properties of two heavy chain antibody fragments (V(H)H), ni3A and pa2H, to differentially detect vascular or parenchymal amyloid-β deposits characteristic for Alzheimer's disease and cerebral amyloid angiopathy.
Externí odkaz:
https://doaj.org/article/345936b88cb54209aa94fbd068f64428
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 911
Phage display technology is frequently used to obtain antigen specific binders with predetermined characteristics. Phage display libraries are often constructed from animals immunized with the antigen of interest. An important point of consideration
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::154326155e3380f0d2b60c30379f84b0
https://pubmed.ncbi.nlm.nih.gov/22886256
https://pubmed.ncbi.nlm.nih.gov/22886256
Publikováno v:
Methods in Molecular Biology ISBN: 9781617799679
Phage display technology is frequently used to obtain antigen specific binders with predetermined characteristics. Phage display libraries are often constructed from animals immunized with the antigen of interest. An important point of consideration
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e65d6cef9f419b03d9be835fd8a6de2
https://doi.org/10.1007/978-1-61779-968-6_15
https://doi.org/10.1007/978-1-61779-968-6_15
Autor:
C. Theo Verrips, Silvère M. van der Maarel, Marion L. Maat-Schieman, Steven M. Greenberg, Brian J. Bacskai, Sjoerd G. van Duinen, Kim S. Rutgers, Matthew P. Frosch, Alexandra van Remoortere, Mark A. van Buchem
Publikováno v:
Neurobiology of Aging, 32(10), 1774-1783
By phage display, llama-derived heavy chain antibody fragments were selected from non-immune and immune libraries and tested for their affinity and specificity for beta amyloid by phage-ELISA, immunohistochemistry and surface plasmon resonance. We id
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::177ea20bcafdefc0602b98c27f1e2226
http://hdl.handle.net/1887/110227
http://hdl.handle.net/1887/110227
Autor:
Rob J.A. Nabuurs, A. G. De Boer, Maarten Rotman, Geert J. Schenk, S.M. van der Maarel, M.A. van Buchem, S. G. Van Duinen, C.T. Verrips, Marion L.C. Maat-Schieman, Kim S. Rutgers, S.A.A. van den Berg
Publikováno v:
Neuroscience, 190, 37-42. Elsevier Limited
Neuroscience, 190, 37-42
Neuroscience, 190, 37-42
Previously selected amyloid beta recognizing heavy chain antibody fragments (VHH) affinity binders derived from the Came lid heavy chain antibody repertoire were tested for their propensity to cross the blood-brain barrier (BBB) using an established
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c550d59751ff34f8b11851a7deb48fd
https://doi.org/10.1016/j.neuroscience.2011.05.076
https://doi.org/10.1016/j.neuroscience.2011.05.076