Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Kim Ry Hejnaes"'
Autor:
Steven J. Burton, Kim Ry Hejnaes, James C. Pearson, Paul R. Morrill, Henrik Valore, Christopher R. Lowe, Svend Ludvigsen, Kenny Sproule
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 740:17-33
A new approach for the identification of ligands for the purification of pharmaceutical proteins by affinity chromatography is described. The technique involves four steps. Selection of an appropriate site on the target protein, design of a complemen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8be211d5cf6de1ced794153364e68d3
https://doi.org/10.1016/s0378-4347(99)00570-8
https://doi.org/10.1016/s0378-4347(99)00570-8
Autor:
E. Mortensen, Thomas Dyrberg, Kim Ry Hejnaes, Michael O. Marshall, A. J. Moody, Esper Boel, F. S. Larsen, I. Svendsen
Publikováno v:
Diabetologia. 38:14-23
The enzymel-glutamic acid decarboxylase is a major autoantigen of the beta cell. Autoantibodies against this enzyme are observed before the onset of insulin-dependent diabetes mellitus (IDDM) in man and may be of predictive value. There is evidence t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcc9b995e59e3e7303eaf320bab08b89
https://doi.org/10.1007/bf02369348
https://doi.org/10.1007/bf02369348
Autor:
Thomas Dyrberg, Kim Ry Hejnaes, M. Høier-Madsen, Allan E. Karlsen, Birgitte K. Michelsen, Jacob S. Petersen, Michael O. Marshall, Esper Boel, Alistar Moody
Publikováno v:
Diabetes. 43:459-467
Autoantibodies to glutamic acid decarboxylase (GAD) are frequent at or before the onset of insulin-dependent diabetes mellitus (IDDM). We have developed a simple, reproducible, and quantitative immunoprecipitation radioligand assay using as antigen i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1e9f31fb7a31fd6982b48c1f17c51c4
https://doi.org/10.2337/diab.43.3.459
https://doi.org/10.2337/diab.43.3.459
Autor:
Thomas Dyrberg, Steinunn Baekkeskov, M. Høier-Madsen, Michael O. Marshall, Jacob S. Petersen, Kim Ry Hejnaes
Publikováno v:
Diabetologia. 36:510-515
Pancreatic beta-cell destruction and development of Type 1 (insulin-dependent) diabetes mellitus are associated with circulating islet cell antibodies. Mice with severe combined immunodeficiency (SCID mice) were reconstituted with peripheral blood mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aeddee7c0f6a32349a30a5daa9667904
https://doi.org/10.1007/bf02743266
https://doi.org/10.1007/bf02743266
Autor:
Alistar Moody, Michael O. Marshall, Jacob S. Petersen, Ole D. Madsen, Thomas Dyrberg, Åke Lernmark, Birgitte K. Michelsen, William Hagopian, Karsten Buschard, Allan E. Karlsen, Natalie Cambon, Kim Ry Hejnaes, Hans Kofod, Steven Russel, Esper Boel
Publikováno v:
Diabetes. 42:484-495
The GABA synthesizing enzyme GAD is a prominent islet cell autoantigen in type I diabetes. The two forms of GAD (GAD64 and GAD67) are encoded by different genes in both rats and humans. By in situ hybridization analysis of rat and human pancreases, e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5cecae03bfcd7f04207172edd175917
https://doi.org/10.2337/diab.42.3.484
https://doi.org/10.2337/diab.42.3.484
Publikováno v:
Bioseparation and Bioprocessing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e4e14b75b3bbfe95f695a1b96f473ef
https://doi.org/10.1002/9783527619641.ch19
https://doi.org/10.1002/9783527619641.ch19
Autor:
K. Rimvall, Thomas Dyrberg, P. N. Jørgensen, Kim Ry Hejnaes, A. J. Moody, Jacob S. Petersen, J. T. Clausen, E. Hasselager
Publikováno v:
Diabetologia. 41(5)
Glutamic acid decarboxylase (GAD) is an important autoantigen in insulin-dependent diabetes mellitus (IDDM), but little is known about its regulation and function in islet cells. We investigated the effects of the GABA-transaminase inhibitor gamma-vi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10bbef8603470b7cf640ab1deb54d63a
https://pubmed.ncbi.nlm.nih.gov/9628269
https://pubmed.ncbi.nlm.nih.gov/9628269
Autor:
Stephen J. Fey, Jørn Nerup, Arkadiusz Nawrocki, Peter Mose Larsen, Thomas Mandrup-Poulsen, Henrik U. Andersen, Kim Ry Hejnaes
Publikováno v:
Andersen, H U, Fey, S J, Larsen, P M, Nawrocki, A, Hejnaes, K R, Mandrup-Poulsen, T & Nerup, J 1997, ' Interleukin-1beta induced changes in the protein expression of rat islets: a computerized database. ', Electrophoresis, vol. 18, no. 11, pp. 2091-103 . https://doi.org/10.1002/elps.1150181136
Udgivelsesdato: 1997-Oct Insulin-dependent diabetes mellitus is caused by an autoimmune destruction of the beta-cells in the islets of Langerhans. The cytokine interleukin 1 inhibits insulin release and is selectively cytotoxic to beta-cells in isola
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c6d4f40d97e9d3800cefcef4fb621ba
https://portal.findresearcher.sdu.dk/da/publications/b10e7aa0-63a6-11dd-b1a1-000ea68e967b
https://portal.findresearcher.sdu.dk/da/publications/b10e7aa0-63a6-11dd-b1a1-000ea68e967b
Publikováno v:
Annals of the New York Academy of Sciences. 782
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e632d9a2c6cba45711e300187a7bc25
https://pubmed.ncbi.nlm.nih.gov/8659913
https://pubmed.ncbi.nlm.nih.gov/8659913
Autor:
Paul E. Høyer, Thomas Dyrberg, Gian Franco Bottazzo, Kim Ry Hejnaes, Michael O. Marshall, Jacob S. Petersen, Stefano Genovese
Publikováno v:
Europe PubMed Central
The contribution of glutamate decarboxylase (Mr 65000) antibodies to the reactivity of islet cell cytoplasmic antibodies with the 'whole' islet staining pattern from patients with newly diagnosed Type I diabetes was investigated. Diluted sera (n = 10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70bf6a0dc5a1b3188ceeb3e05c90bb89
https://pubmed.ncbi.nlm.nih.gov/7980851
https://pubmed.ncbi.nlm.nih.gov/7980851