Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Kim Peterson-Yantorno"'
Autor:
Chi Ting Leung, Ang Li, W. Daniel Stamer, Mortimer M. Civan, Kim Peterson-Yantorno, Juni Banerjee
Publikováno v:
Experimental Eye Research. 96:4-12
Lowering intraocular pressure (IOP) is currently the only strategy documented to slow the onset and progression of glaucomatous blindness. Ouabain, a cardiotonic glycoside inhibitor of Na(+), K(+)-activated ATPase, was recently reported to enhance ou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e43352029d0841112b60c8103b453848
https://doi.org/10.1016/j.exer.2012.01.009
https://doi.org/10.1016/j.exer.2012.01.009
Autor:
Claire H. Mitchell, Chi Ting Leung, Mortimer M. Civan, W. Daniel Stamer, Ang Li, Kim Peterson-Yantorno
Publikováno v:
Journal of Cellular Physiology. 227:172-182
Our guiding hypothesis is that ecto-enzymatic conversion of extracellular ATP to adenosine activates A(1) adenosine receptors, reducing resistance to aqueous humor outflow and intraocular pressure. The initial step in this purinergic regulation is AT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::027c784ec971e03ad8d30ccf7d35ed7f
https://doi.org/10.1002/jcp.22715
https://doi.org/10.1002/jcp.22715
Autor:
Juni Banerjee, Chi Ting Leung, Ang Li, W. Daniel Stamer, Kim Peterson-Yantorno, Mortimer M. Civan
Publikováno v:
Cellular Physiology and Biochemistry. 28:1135-1144
The only effective intervention to slow onset and progression of glaucomatous blindness is to lower intraocular pressure (IOP). Among other modulators, adenosine receptors (ARs) exert complex regulation of IOP. Agonists of A(3)ARs in the ciliary epit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1e96d1fc5057769e9fb23ddec04946d
https://doi.org/10.1159/000335865
https://doi.org/10.1159/000335865
Publikováno v:
American Journal of Physiology-Cell Physiology. 299:C1308-C1317
ATP release by nonpigmented (NPE) and pigmented (PE) ciliary epithelial cells is the enabling step in purinergic regulation of aqueous humor formation, but the release pathways are unknown. We measured ATP release from primary cultures of bovine mixe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68497c12abad32a79cf4ebcd8e998b5f
https://doi.org/10.1152/ajpcell.00333.2010
https://doi.org/10.1152/ajpcell.00333.2010
Autor:
Kim Peterson-Yantorno, Zhan Guo Gao, Kenneth A. Jacobson, Lak Shin Jeong, Pedro Besada, Marcel Y. Avila, Zhao Wang, Richard A. Stone, Bhalchandra V. Joshi, Mortimer M. Civan, Chi Wai Do
Publikováno v:
Experimental Eye Research. 90:146-154
The purpose of the study was to determine whether novel, selective antagonists of human A 3 adenosine receptors (ARs) derived from the A 3 -selective agonist Cl-IB-MECA lower intraocular pressure (IOP) and act across species. IOP was measured invasiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67732500de369de08dc10411f7db9ec8
https://doi.org/10.1016/j.exer.2009.10.001
https://doi.org/10.1016/j.exer.2009.10.001
Autor:
J.C. Fleischhauer, W. Daniel Stamer, M. M. Civan, Richard A. Stone, Mike O. Karl, Kim Peterson-Yantorno, Claire H. Mitchell
Publikováno v:
American Journal of Physiology-Cell Physiology. 288:C784-C794
Intraocular pressure is directly dependent on aqueous humor flow into, and resistance to flow out of, the eye. Adenosine has complex effects on intraocular pressure. Stimulation of A1and A2Aadenosine receptors changes intraocular pressure oppositely,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1980d4d8c005b113c1de556c139032b4
https://doi.org/10.1152/ajpcell.00333.2004
https://doi.org/10.1152/ajpcell.00333.2004
Publikováno v:
American Journal of Physiology-Cell Physiology. 287:C1003-C1011
The eye’s aqueous humor is secreted by a bilayered ciliary epithelium comprising pigmented (PE) and nonpigmented (NPE) epithelial cell layers. Stromal Cl−enters the PE cells and crosses gap junctions to the NPE cells for release into the aqueous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae077cf64da66969971f0955a3f9598e
https://doi.org/10.1152/ajpcell.00175.2004
https://doi.org/10.1152/ajpcell.00175.2004
Autor:
W. Daniel Stamer, Claire H. Mitchell, J.C. Fleischhauer, Mortimer M. Civan, Kim Peterson-Yantorno
Publikováno v:
American Journal of Physiology-Cell Physiology. 283:C315-C326
The volume of certain subpopulations of trabecular meshwork (TM) cells may modify outflow resistance of aqueous humor, thereby altering intraocular pressure. This study examines the contribution that Na+/H+, Cl−/HCO[Formula: see text]exchange, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff5948dd8915cfab3e16ee82c574f639
https://doi.org/10.1152/ajpcell.00544.2001
https://doi.org/10.1152/ajpcell.00544.2001
Autor:
Kim Peterson-Yantorno, Ang Li, W. Daniel Stamer, Mortimer M. Civan, Huan Ouyang, Juni Banerjee, Chi-Ting Leung
Publikováno v:
Investigative Ophthalmology & Visual Science
Purpose Trabecular meshwork (TM) cell volume is a determinant of aqueous humor outflow resistance, and thereby IOP. Regulation of TM cell volume depends on chloride ion (Cl-) release through swelling-activated channels (ICl,Swell), whose pore is form
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06b66a1f7e2712bd7bb3dae0ade44355
https://doi.org/10.1167/iovs.16-20188
https://doi.org/10.1167/iovs.16-20188
Autor:
Charles W. McLaughlin, Robert D. Purves, Anthony D. C. Macknight, David A. Carré, Mortimer M. Civan, Claire H. Mitchell, David Peart, Kim Peterson-Yantorno
Publikováno v:
American Journal of Physiology-Cell Physiology. 281:C865-C875
The β-adrenergic antagonist timolol reduces ciliary epithelial secretion in glaucomatous patients. Whether inhibition is mediated by reducing cAMP is unknown. Elemental composition of rabbit ciliary epithelium was studied by electron probe X-ray mic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d82d1b8335fa4ac50f00dd10fb7e1a7
https://doi.org/10.1152/ajpcell.2001.281.3.c865
https://doi.org/10.1152/ajpcell.2001.281.3.c865