Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Kim P. Larsson"'
Differentiation dependent expression of TRPA1 and TRPM8 channels in IMR-32 human neuroblastoma cells
Autor:
Johnny Näsman, Lauri M. Louhivuori, Verna Louhivuori, Genevieve Bart, Tommy Nordström, Karl E.O. Åkerman, Kim P. Larsson, A. Koivisto
Publikováno v:
Journal of Cellular Physiology. 221:67-74
TRPA1 and TRPM8 are transient receptor potential (TRP) channels involved in sensory perception. TRPA1 is a non-selective calcium permeable channel activated by irritants and proalgesic agents. TRPM8 reacts to chemical cooling agents such as menthol.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cb04f7e17fceafd848625f0ca36ca45
https://doi.org/10.1002/jcp.21828
https://doi.org/10.1002/jcp.21828
Autor:
Eero Castrén, Seppo Heinonen, Ben A. Oostra, Cathy E. Bakker, Kim P. Larsson, Virve Kärkkäinen, Maija L. Castrén, Karl E.O. Åkerman, Topi A. Tervonen
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of Ame, 102(49), 17834-17839. National Academy of Sciences
Fragile X syndrome, a common form of inherited mental retardation, is caused by the absence of the fragile X mental retardation protein (FMRP) due to a mutation in the FMR1 gene. We investigated the differentiation of neural stem cells generated from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e775809bb172e28b7d39bc9d2925b94b
https://hdl.handle.net/1765/68206
https://hdl.handle.net/1765/68206
Autor:
Hanna M. Peltonen, Miia Antikainen, Annika Penttonen, Kim P. Larsson, Genevieve Bart, Lauri M. Louhivuori, Jyrki P. Kukkonen, Karl E.O. Åkerman
Publikováno v:
Journal of Biological Chemistry. 280:1771-1781
The orexins are peptide transmitters/hormones, which exert stimulatory actions in many types of cells via the G-protein-coupled OX(1) and OX(2) receptors. Our previous results have suggested that low (subnanomolar) concentrations of orexin-A activate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c71dc95633fbd920f96db0a74f8c3251
https://doi.org/10.1074/jbc.m406073200
https://doi.org/10.1074/jbc.m406073200
Autor:
Sanna T.H. Uotila, Karl E.O. Åkerman, Jyrki P. Kukkonen, Kim P. Larsson, Johanna Magga, Johnny Näsman, Karl-Heinz Herzig
Publikováno v:
Biochemical and Biophysical Research Communications. 309:209-216
Orexins are newly discovered neuropeptides regulating feeding and vigilance and have been detected in neuroendocrine cells of the gut. Potential neuroendocrine functions of orexin are unknown. Therefore, the effects of orexin-A on the intestinal neur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a646455ba61bad15f1f77ba6354406ea
https://doi.org/10.1016/s0006-291x(03)01563-8
https://doi.org/10.1016/s0006-291x(03)01563-8
Autor:
Garry Wong, Kim P. Larsson, Stefan Stamm, Annakaisa Haapasalo, Peter Stoilov, Ilkka Sipola, Eero Castrén, Karl E.O. Åkerman
Publikováno v:
Journal of Biological Chemistry. 277:43160-43167
Brain-derived neurotrophic factor (BDNF) signaling through its receptor TRKB modulates survival, differentiation, and activity of neurons. BDNF activates TRKB on the cell surface, which leads to the initiation of intracellular signaling cascades and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a395287f49b4d3769599345b809f876c
https://doi.org/10.1074/jbc.m205202200
https://doi.org/10.1074/jbc.m205202200
Autor:
Hanna M. Peltonen, Johnny Näsman, Karl E.O. Åkerman, Lauri M. Louhivuori, Kim P. Larsson, Genevieve Bart
We studied the cellular response to orexin type 1 receptor (OX1R) stimulation in differentiated IMR-32 neuroblastoma cells.In vitrodifferentiation of IMR-32 cells with 5-bromo-2′-deoxyuridine leads to a neuronal phenotype with long neurite extensio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1f56061e465852ecba88bac4bdb757e
https://europepmc.org/articles/PMC6674737/
https://europepmc.org/articles/PMC6674737/
Autor:
Kim P, Larsson, Hanna M, Peltonen, Genevieve, Bart, Lauri M, Louhivuori, Annika, Penttonen, Miia, Antikainen, Jyrki P, Kukkonen, Karl E O, Akerman
Publikováno v:
The Journal of biological chemistry. 280(3)
The orexins are peptide transmitters/hormones, which exert stimulatory actions in many types of cells via the G-protein-coupled OX(1) and OX(2) receptors. Our previous results have suggested that low (subnanomolar) concentrations of orexin-A activate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::edba00eb2cdf1a9b54d858e4ac6f1356
https://pubmed.ncbi.nlm.nih.gov/15537648
https://pubmed.ncbi.nlm.nih.gov/15537648
Autor:
Kim P. Larsson, Michael J. Courtney, Ramin Shariatmadari, Karl E.O. Åkerman, Jelena Krjukova, Jyrki P. Kukkonen
Publikováno v:
Cell calcium. 36(5)
Communication between neuronal and non-neuronal is called volume transmission when the released neurotransmitter (NT) acts via diffusion and affects several target cells. Both the neurosecretory and postsynaptic cell responses are linked to [Ca2+]i e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff29d575157f6824341ae4c19651c8cc
https://pubmed.ncbi.nlm.nih.gov/15451623
https://pubmed.ncbi.nlm.nih.gov/15451623
Autor:
Kai Kaarniranta, Kim P. Larsson, Giedrius Kalesnykas, Karl E.O. Åkerman, Minna Niittykoski, Hannu Uusitalo
Publikováno v:
Investigative Opthalmology & Visual Science. 51:6387
Purpose To investigate calcium signaling in a rat experimental model of glaucoma. Methods A method for labeling ganglion cell layer (GCL) neurons with the calcium indicator Fura-2 in flat-mounted retinas of adult rats was established. Pharmacological
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddc39cbe35db69e63a56c98d4c5a878d
https://doi.org/10.1167/iovs.09-3816
https://doi.org/10.1167/iovs.09-3816