Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Kim M.T. de Bruyn"'
Autor:
Jan-Willem N. Akkerman, Fried J. T. Zwartkruis, Kim M.T. de Bruyn, Johan de Rooij, Johannes L. Bos
Publikováno v:
Journal of Biological Chemistry. 278:22412-22417
The small GTPase Rap1, which is activated by a large variety of stimuli, functions in the control of integrin-mediated cell adhesion. Here we show that in human megakaryocytes and several other commonly used hematopoietic cell lines such as K562, Jur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec1db48204566016390c33e2b2c7ce5d
https://doi.org/10.1074/jbc.m212036200
https://doi.org/10.1074/jbc.m212036200
Autor:
Alida M.M. de Vries-Smits, Boudewijn M.T. Burgering, A. Pieter J. van den Heuvel, Jurgen Riedl, Kim M.T. de Bruyn, Pascale F. Dijkers, Pascale C. van Weeren
Publikováno v:
Journal of Cell Science. 115:3957-3966
The serine/threonine kinase protein kinase B (PKB/c-Akt) acts downstream of the lipid kinase phosphoinositide 3-kinase (PI3K) and functions as an essential mediator in many growth-factor-induced cellular responses such as cell cycle regulation, cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d0fcdeb1dd28ce2bc86edfa6ef69f42
https://doi.org/10.1242/jcs.00069
https://doi.org/10.1242/jcs.00069
Autor:
Holger Rehmann, Johannes L. Bos, Johan de Rooij, Alfred H. Wittinghofer, Kim M.T. de Bruyn, Rob M. F. Wolthuis, Robbert H. Cool, Joep Wesenbeek
Publikováno v:
Journal of Biological Chemistry. 275:29761-29766
Ral is a ubiquitously expressed Ras-like small GTPase. Several guanine nucleotide exchange factors for Ral have been identified, including members of the RalGDS family, which exhibit a Ras binding domain and are regulated by binding to RasGTP. Here w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb44801eedf050b8378494869884897d
https://doi.org/10.1074/jbc.m001160200
https://doi.org/10.1074/jbc.m001160200
Essential Role for Protein Kinase B (PKB) in Insulin-induced Glycogen Synthase Kinase 3 Inactivation
Autor:
Boudewijn M.T. Burgering, Pascale C. van Weeren, Kim M.T. de Bruyn, Johan Van Lint, Alida M.M. de Vries-Smits
Publikováno v:
Journal of Biological Chemistry. 273:13150-13156
Activation of phosphatidylinositide 3'-OH kinase (PI 3-kinase) is implicated in mediating a variety of growth factor-induced responses, among which are the inactivation of glycogen synthase kinase-3 (GSK-3) and the activation of the serine/threonine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::57fcdaa895c46f8856ace44d4e64d69a
https://doi.org/10.1074/jbc.273.21.13150
https://doi.org/10.1074/jbc.273.21.13150
Publikováno v:
Journal of Biological Chemistry, 277, 33, pp. 29468-76
Journal of Biological Chemistry, 277, 29468-29476. Amer soc biochemistry molecular biology inc
Journal of biological chemistry, 277(33), 29468-29476. American Society for Biochemistry and Molecular Biology Inc.
Journal of Biological Chemistry, 277, 29468-76
Journal of Biological Chemistry, 277, 33, pp. 29468-29476
Journal of Biological Chemistry, 277, 29468-29476. Amer soc biochemistry molecular biology inc
Journal of biological chemistry, 277(33), 29468-29476. American Society for Biochemistry and Molecular Biology Inc.
Journal of Biological Chemistry, 277, 29468-76
Journal of Biological Chemistry, 277, 33, pp. 29468-29476
Contains fulltext : 142510.pdf (Publisher’s version ) (Open Access) In T-lymphocytes the Ras-like small GTPase Rap1 plays an essential role in stimulus-induced inside-out activation of integrin LFA-1 (alpha(L)beta(2)) and VLA-4 (alpha(4)beta(1)). H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cafaa976b1078267107e2601a52d1baf
https://hdl.handle.net/2066/142510
https://hdl.handle.net/2066/142510
