Clinical Unmet Needs in the Treatment of Adrenal Crisis: Importance of the Patient’s Perspective

Autor: Kim M. J. A. Claessen, Cornelie D. Andela, Nienke R. Biermasz, Alberto M. Pereira

Publikováno v: Frontiers in Endocrinology, Vol 12 (2021)

Adrenal crisis is the most severe manifestation of adrenal insufficiency (AI), but AI can present with variable signs and symptoms of gradual severity. Despite current hormone replacement strategies, adrenal crisis is still one of the leading causes

Externí odkaz: https://doaj.org/article/0f940d921fed43d0800e92e957d763d5

Progression of acromegalic arthropathy in long-term controlled acromegaly patients: 9 years of longitudinal follow-up

Autor: Alberto M. Pereira, Kim M J A Claessen, Wouter R van Furth, Nienke R. Biermasz, Herman M. Kroon, Iris C. M. Pelsma, Margreet Kloppenburg

Publikováno v: Journal of Clinical Endocrinology and Metabolism, 106(1), 188-200. ENDOCRINE SOC
Pelsma, I C M, Biermasz, N R, van Furth, W R, Pereira, A M, Kroon, H M, Kloppenburg, M & Claessen, K M J A 2021, ' Progression of acromegalic arthropathy in long-term controlled acromegaly patients: 9 years of longitudinal follow-up ', Journal of Clinical Endocrinology and Metabolism, vol. 106, no. 1, pp. 188-200 . https://doi.org/10.1210/clinem/dgaa747
Journal of Clinical Endocrinology and Metabolism, 106(1), 188-200. The Endocrine Society

Context Joint complaints in patients with acromegaly are common, although the long-term disease course is largely unknown. Objective This study aims to evaluate the long-term course of acromegalic arthropathy. Design and Setting A prospective longitu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ef01bc72878ace318692946b0f76912
https://doi.org/10.1210/clinem/dgaa747

Low sclerostin levels after long-term remission of acromegaly

Autor: Antoon H van Lierop, Alberto M. Pereira, Herman M. Kroon, Natasha M. Appelman-Dijkstra, Kim M J A Claessen, Nienke R. Biermasz, Iris C. M. Pelsma

Publikováno v: Endocrine
Endocrine, 75, 228-238. SPRINGER

Purpose Bone health is compromised in acromegaly resulting in vertebral fractures (VFs), regardless of biochemical remission. Sclerostin is a negative inhibitor of bone formation and is associated with increased fracture risk in the general populatio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8d46fa54b569546282ab7852cde9e7e
https://hdl.handle.net/1887/3237851

State of the art of patient-reported outcomes in acromegaly or GH deficiency

Autor: Merel van der Meulen, Amir H Zamanipoor Najafabadi, Leonie H A Broersen, Jan W Schoones, Alberto M Pereira, Wouter R van Furth, Kim M J A Claessen, Nienke R Biermasz

Publikováno v: Journal of Clinical Endocrinology and Metabolism, 107(5), 1225-1238. OXFORD UP

Context Insight into the current landscape of patient-reported outcome (PRO) measures (PROM) and differences between PROs and conventional biochemical outcomes is pivotal for future implementation of PROs in research and clinical practice. Therefore,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9207d84fb13d8ad1eb3414b7835a2570
https://hdl.handle.net/1887/3563108

Progression of vertebral fractures in long-term controlled acromegaly: A 9-year follow-up study

Autor: Nienke R. Biermasz, Kim M J A Claessen, Margreet Kloppenburg, Herman M. Kroon, Iris C. M. Pelsma, W. R. van Furth, Alberto M. Pereira, Natasha M. Appelman-Dijkstra

Publikováno v: European Journal of Endocrinology, 183(4), 427-437. BIOSCIENTIFICA LTD

Objective: Growth hormone (GH) and insulin-like growth factor 1 (IGF-1) excess results in both reversible and irreversible musculoskeletal damage, including increased vertebral fracture (VF) risk. The prevalence of VFs is approximately 60% in control

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adcae6332b6fbd0d69fd95362301ed80
https://doi.org/10.1530/endoabs.70.aep215