Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Kim L. Roberts"'
Autor:
Conor McGinn, Robert Scott, Niamh Donnelly, Kim L. Roberts, Marina Bogue, Christine Kiernan, Michael Beckett
Publikováno v:
Frontiers in Robotics and AI, Vol 7 (2021)
The importance of infection control procedures in hospital radiology departments has become increasingly apparent in recent months as the impact of COVID-19 has spread across the world. Existing disinfectant procedures that rely on the manual applica
Externí odkaz:
https://doaj.org/article/6ccb5da34c66461e91de8c20cb599078
Autor:
Neeltje van Doremalen, Holly Shelton, Kim L Roberts, Ian M Jones, Ray J Pickles, Catherine I Thompson, Wendy S Barclay
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e25755 (2011)
The first pandemic of the 21(st) century, pandemic H1N1 2009 (pH1N1 2009), emerged from a swine-origin source. Although human infections with swine-origin influenza have been reported previously, none went on to cause a pandemic or indeed any sustain
Externí odkaz:
https://doaj.org/article/b179ac49d2924f21bdc0e3d62710e40f
Autor:
Margaret A Scull, Laura Gillim-Ross, Celia Santos, Kim L Roberts, Elena Bordonali, Kanta Subbarao, Wendy S Barclay, Raymond J Pickles
Publikováno v:
PLoS Pathogens, Vol 5, Iss 5, p e1000424 (2009)
Transmission of avian influenza viruses from bird to human is a rare event even though avian influenza viruses infect the ciliated epithelium of human airways in vitro and ex vivo. Using an in vitro model of human ciliated airway epithelium (HAE), we
Externí odkaz:
https://doaj.org/article/be1395fa66a145cabdff2563eefa0d97
Autor:
J. S. Malik Peiris, Stuart M. Haslam, Renee W. Y. Chan, Hui-Ling Yen, Wendy S. Barclay, Alfred King-Yin Lam, Nan Jia, Gillian M. Air, John M. Nicholls, Anne Dell, Kim L. Roberts
Publikováno v:
The Journal of Biological Chemistry
Background: The ferret is a key animal model to study the transmission characteristics of influenza viruses. Results: Characterization of ferret respiratory tract tissues identified influenza virus glycan receptors. Conclusion: Species-specific influ
Autor:
Cliona O'Farrelly, Rebecca Mahony, Nigel J. Stevenson, Siobhan Gargan, Andrew G. Bowie, Kim L. Roberts, Sinead E. Keating, Nollaig M. Bourke
Publikováno v:
Cellular and molecular life sciences : CMLS. 74(9)
The cytokine, Interferon (IFN)-α, induces a wide spectrum of anti-viral mediators, via the Janus kinase/signal transducer and activator of transcription (JAK/STAT) pathway. STAT1 and STAT2 are well characterised to upregulate IFN-stimulated gene (IS
Autor:
Saranya Sridhar, Shaima Begom, Kim L. Roberts, Peter J. M. Openshaw, Thedi Ziegler, Wendy S. Barclay, Alison Bermingham, Ajit Lalvani
Publikováno v:
European Journal of Immunology. 42:2913-2924
The 2009/10 pandemic (pH1N1) highlighted the need for vaccines conferring heterosubtypic immunity against antigenically shifted influenza strains. Although cross-reactive T cells are strong candidates for mediating heterosubtypic immunity, little is
Autor:
Silke Schepelmann, Lauren Parker, Ruth A. Elderfield, Wendy S. Barclay, Kim L. Roberts, Peter Stilwell
Publikováno v:
The Journal of general virology. 96(8)
Ferrets have become the model animal of choice for influenza pathology and transmission experiments as they are permissive and susceptible to human influenza A viruses. However, inoculation of ferrets with mumps virus (MuV) did not lead to successful
Publikováno v:
The Journal of General Virology
The H5N1 influenza A viruses have circulated widely in the avian population for 10 years with only sporadic infection of humans observed and no sustained human to human transmission. Vaccination against potential pandemic strains is one strategy in p
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 8, p e43303 (2012)
PLoS ONE, Vol 7, Iss 8, p e43303 (2012)
During the early phase of the 2009 influenza pandemic, attempts were made to contain the spread of the virus. Success of reactive control measures may be compromised if the proportion of transmission that occurs before overt clinical symptoms develop
Autor:
Wendy S. Barclay, Ben Johnson, Peter Stilwell, Holly Shelton, Lorian C. Hartgroves, Matthew J. Smith, Kim L. Roberts
Publikováno v:
The Journal of General Virology
Influenza viruses readily mutate by accumulating point mutations and also by reassortment in which they acquire whole gene segments from another virus in a co-infected host. The NS1 gene is a major virulence factor of influenza A virus. The effects o