Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Kim L. Jensen"'
Publikováno v:
Chemistry - A European Journal. 21:7379-7383
In this communication, we report a straightforward synthesis of enantiomerically pure 2-alkyl azetidines. The protocol is based on a highly regioselective nickel-catalyzed cross-coupling of aliphatic organozinc reagents with an aziridine that feature
Publikováno v:
Journal of the American Chemical Society. 136:11145-11152
Herein, we report the first ligand-controlled, nickel-catalyzed cross-coupling of aliphatic N-tosylaziridines with aliphatic organozinc reagents. The reaction protocol displays complete regioselectivity for reaction at the less hindered C-N bond, and
Publikováno v:
Organic Syntheses
Poulsen, P H, Overgaard, M K, Jensen, K L & Jørgensen, K A 2014, ' Enantioselective Organocatalytic α-Arylation of Aldehydes ', Organic Synthesis, vol. 91, pp. 175-184 . https://doi.org/10.15227/orgsyn.091.0175
Poulsen, P H, Overgaard, M K, Jensen, K L & Jørgensen, K A 2014, ' Enantioselective Organocatalytic α-Arylation of Aldehydes ', Organic Synthesis, vol. 91, pp. 175-184 . https://doi.org/10.15227/orgsyn.091.0175
This article describes an organocatalytic, enantioselective α- arylation of aldehydes, in which quinones are applied as the aromatic partner, to afford optically active α-arylated aldehydes. Following the addition/aromatization sequence, subsequent
Publikováno v:
Jensen, K L, Poulsen, P H, Donslund, B, Morana, F & Jørgensen, K A 2012, ' Asymmetric Synthesis of gamma-Nitroesters by an Organocatalytic One-Pot Strategy ', Organic Letters, vol. 14, pp. 1516-1519 . https://doi.org/10.1021/ol3002514
An enantioselective synthesis of γ-nitroesters by a one-pot asymmetric Michael addition/oxidative esterification of α,β-unsaturated aldehydes is presented. The procedure is based on merging the enantioselective organocatalytic nitroalkane addition
Autor:
Kim L. Jensen, J. A. Alexander, David A. Katzka, Thomas C. Smyrk, Anita Arora, Amy E. Foxx-Orenstein, Yvonne Romero, Dawn L. Francis, Sara Linker Nord
Publikováno v:
Alimentary Pharmacology & Therapeutics. 35:300-307
Aliment Pharmacol Ther 2012; 35: #–# Summary Background The consensus statements for eosinophilic oesophagitis recommend that ambulatory pH monitoring is one means of determining if gastro-oesophageal reflux is the cause of oesophageal eosinophilia
Publikováno v:
Jacobsen, C B, Jensen, K L, Udmark, J R K & Jørgensen, K A 2011, ' Organocatalytic iminium ion/carbene reaction cascade for the formation of optically active 2,4-disubstituted cyclopentenones ', Organic Letters, vol. 13, no. 18, pp. 4790-4793 . https://doi.org/10.1021/ol2018104
An organocatalytic iminium ion/N-heterocyclic carbene (NHC) cascade reaction between β-keto phenyltetrazolesulfones and α,β- unsaturated aldehydes, providing direct access to optically active 2,4-disubstituted cyclopent-2-enones, has been develope
Publikováno v:
Monge, D, Jensen, K L, Marín, I & Jørgensen, K A 2011, ' Synthesis of 1,2,4-Triazolines Base-Catalyzed Hydrazination/Cyclization Cascade of α-Isocyano Esters and Amides. ', Organic Letters, vol. 13, no. 2, pp. 328 . https://doi.org/10.1021/ol102812c
A convenient, efficient synthesis of 1,2,4-triazolines from α-isocyano esters/amides and azodicarboxylates is presented. The developed reaction cascade is based on a base-catalyzed hydrazination-type reaction followed by a subsequent cyclization pro
Autor:
Anders Fomsgaard, Lars Peter Nielsen, Karoline Bragstad, Cyril Jean-Marie Martel, Kim L. Jensen, Joakim S. Thomsen, Bent Aasted
Publikováno v:
Influenza and Other Respiratory Viruses. 5:13-23
Please cite this paper as: Bragstad et al. (2010) Pandemic influenza 1918 H1N1 and 1968 H3N2 DNA vaccines induce cross-reactive immunity in ferrets against infection with viruses drifted for decades. Influenza and Other Respiratory Viruses 5(1), 13
Publikováno v:
Monge, D, Jensen, K L, Franke, P T, Lykke, L & Jørgensen, K A 2010, ' Asymmetric One-Pot Sequential Organo-and Gold Catalysis for the Enantioselective Synthesis of Dihydropyrrole Derivatives ', Chemistry: A European Journal, vol. 16, no. 31, pp. 9478-9484 .
A direct asymmetric one-pot synthesis of optically active 2,3-dihy- dropyrroles from propargylated malo- nonitrile and N-Boc-protected (Boc = tert-butoxycarbonyl) imines is present- ed. The approach is based on a bifunc- tional organocatalytic Mannic
Publikováno v:
Reproduction in Domestic Animals. 43:760-763
Tumours are rare in the bovine testicle. A case of malignant Sertoli cell tumour in a 29-month-old Simmenthal bull that was hospitalized with a history of severe unilateral scrotal swelling is reported. On inspection and palpation, the scrotal sac wa