Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Kim L. Harland"'
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Effector CD8+ T cells generally produce type-1 cytokines and mediators of the perforin/granzyme cytolytic pathway, yet type-2-polarized CD8+ cells (Tc2) are detected in type-2 (T2) cytokine-driven diseases such as asthma. It is unclear whether T2 cyt
Externí odkaz:
https://doaj.org/article/565247fcc9ff4a8ab598c7e856394098
Autor:
Thi H. O. Nguyen, Jane Davies, Aeron C. Hurt, Carolien E van de Sandt, Malet Aban, Damian A. Oyong, Marios Koutsakos, Kim L. Harland, Steven Y. C. Tong, Jessica R. Webb, Katie L. Flanagan, Cath Blacker, Adam K. Wheatley, Peter C. Doherty, Jane Nelson, Louise C. Rowntree, Amy W. Chung, Timon Damelang, Anngie Everitt, Katherine Kedzierska, Maria Auladell, E. Bridie Clemens, Stephen J. Kent, Luca Hensen, Magdalena Plebanski, Bruce D. Wines, Jessica R. Loughland, P. Mark Hogarth, Adrian Miller
Publikováno v:
Proceedings of the National Academy of Sciences
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, 118(41). National Academy of Sciences
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, 118(41). National Academy of Sciences
Significance Indigenous populations worldwide are highly susceptible to influenza virus infections. Vaccination with inactivated virus is highly recommended to protect Indigenous populations, including Indigenous Australians. There is no study to dat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8177d032c766c8c1ba09d40bd774890
https://doi.org/10.1073/pnas.2109388118
https://doi.org/10.1073/pnas.2109388118
Autor:
Anne Kelso, Simone Nüssing, Luca Hensen, Stephen J. Turner, Katherine Kedzierska, Annette Fox, Kim L. Harland
Publikováno v:
The Journal of Immunology. 201:3282-3293
Naive CD8+ T cells show phenotypic, functional, and epigenetic plasticity, enabling differentiation into distinct cellular states. However, whether memory CD8+ T cells demonstrate similar flexibility upon recall is poorly understood. We investigated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82c64bec79affaea64f3090c23fa2939
https://doi.org/10.4049/jimmunol.1701672
https://doi.org/10.4049/jimmunol.1701672
Autor:
E. Bridie Clemens, Cath Blacker, Magdalena Plebanski, Adam K. Wheatley, Kim L. Harland, Jane Nelson, Carolien E. van de Sandt, Amy W. Chung, Steven Y. C. Tong, Timon Damelang, Stephen J. Kent, Anngie Everitt, Katherine Kedzierska, Aeron C. Hurt, Thi H. O. Nguyen, Jessica R. Loughland, Jane Davies, Maria Auladell, Luca Hensen, Malet Aban, Jessica R. Webb, Katie L. Flanagan, Bruce D. Wines, Damian A. Oyong, Marios Koutsakos, Louise C. Rowntree, P. Mark Hogarth, Adrian Miller
Publikováno v:
SSRN Electronic Journal.
Background: Morbidity and mortality rates from seasonal and pandemic influenza occur disproportionately in high-risk groups, including Indigenous people globally. Although vaccination against influenza is recommended for those most at risk, studies o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b05c3db87774c6153e13ffffe5e10497
https://doi.org/10.2139/ssrn.3781631
https://doi.org/10.2139/ssrn.3781631
Autor:
Stephen J. Turner, Kylie M. Quinn, Annette Fox, Xavier Y.X. Sng, Liyen Loh, Haroon Naeem, David R. Powell, Jasmine Li, Peter C. Doherty, Nicole L. La Gruta, Thi H. O. Nguyen, Kim L. Harland, Rosela Webster, Moshe Olshanksy, Katherine Kedzierska, Brendan E. Russ, Tony Tiganis, Kirill Tsyganov, Florian Wiede, Chantelle Blyth
Publikováno v:
Cell Reports. 23:3512-3524
Age-associated decreases in primary CD8+ T cell responses occur, in part, due to direct effects on naive CD8+ T cells to reduce intrinsic functionality, but the precise nature of this defect remains undefined. Aging also causes accumulation of antige
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e08dd6130bb355e9fe7cd7687b741a2
https://doi.org/10.1016/j.celrep.2018.05.057
https://doi.org/10.1016/j.celrep.2018.05.057
Autor:
Kim L, Harland, Annette, Fox, Simone, Nüssing, Luca, Hensen, Katherine, Kedzierska, Stephen J, Turner, Anne, Kelso
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 201(11)
Naive CD8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::20c4b6bd5ebd656457fb9798bb592040
https://pubmed.ncbi.nlm.nih.gov/30366957
https://pubmed.ncbi.nlm.nih.gov/30366957
Autor:
Kylie M, Quinn, Annette, Fox, Kim L, Harland, Brendan E, Russ, Jasmine, Li, Thi H O, Nguyen, Liyen, Loh, Moshe, Olshanksy, Haroon, Naeem, Kirill, Tsyganov, Florian, Wiede, Rosela, Webster, Chantelle, Blyth, Xavier Y X, Sng, Tony, Tiganis, David, Powell, Peter C, Doherty, Stephen J, Turner, Katherine, Kedzierska, Nicole L, La Gruta
Publikováno v:
Cell reports. 23(12)
Age-associated decreases in primary CD8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::94e21b661e21bd124eceac0ba2032dab
https://pubmed.ncbi.nlm.nih.gov/29924995
https://pubmed.ncbi.nlm.nih.gov/29924995
Autor:
E. Bridie Day, Stephen J. Turner, Brendan E. Russ, Peter C. Doherty, Simon H. Apte, Anne Kelso, Kim L. Harland
Publikováno v:
Nature Communications
Modulation of CD8 coreceptor levels can profoundly affect T-cell sensitivity to antigen. Here we show that the heritable downregulation of CD8 during type 2 polarization of murine CD8+ effector T cells in vitro and in vivo is associated with CpG meth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57523d4d990e0b1fa0f23fbbb908281e
https://pubmed.ncbi.nlm.nih.gov/24675400
https://pubmed.ncbi.nlm.nih.gov/24675400