Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Kim L, de Luca"'
Autor:
Kim L. de Luca, Pim M. J. Rullens, Magdalena A. Karpinska, Sandra S. de Vries, Agnieszka Gacek-Matthews, Lőrinc S. Pongor, Gaëlle Legube, Joanna W. Jachowicz, A. Marieke Oudelaar, Jop Kind
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Accurate repair of DNA damage is critical for maintenance of genomic integrity and cellular viability. Because damage occurs non-uniformly across the genome, single-cell resolution is required for proper interrogation, but sensitive detectio
Externí odkaz:
https://doaj.org/article/4a8adea22a094f2e87579c732274e6d0
Accurate repair of DNA damage is critical for maintenance of genomic integrity and cellular survival. Because damage occurs non-uniformly across the genome, single-cell resolution is required for proper interrogation, but sensitive detection has rema
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9483fb2775a8a37d194688904e5851bf
https://doi.org/10.1101/2023.05.10.540169
https://doi.org/10.1101/2023.05.10.540169
Autor:
Silke J.A. Lochs, Robin H. van der Weide, Kim L. de Luca, Tessy Korthout, Ramada E. van Beek, Hiroshi Kimura, Jop Kind
Gene expression programs result from the collective activity of many regulatory factors. To obtain insight into the mechanisms that govern gene regulation, it is imperative to study their combined mode of action and interconnectivity. However, it has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::48ceea3792b260d90cd336cf2c83a74f
https://doi.org/10.1101/2023.01.18.524584
https://doi.org/10.1101/2023.01.18.524584
Autor:
Sebastiaan van Heesch, Marieke Simonis, Markus J. van Roosmalen, Vamsee Pillalamarri, Harrison Brand, Ewart W. Kuijk, Kim L. de Luca, Nico Lansu, A. Koen Braat, Androniki Menelaou, Wensi Hao, Jeroen Korving, Simone Snijder, Lars T. van der Veken, Ron Hochstenbach, Alida C. Knegt, Karen Duran, Ivo Renkens, Najla Alekozai, Myrthe Jager, Sarah Vergult, Björn Menten, Ewart de Bruijn, Sander Boymans, Elly Ippel, Ellen van Binsbergen, Michael E. Talkowski, Klaske Lichtenbelt, Edwin Cuppen, Wigard P. Kloosterman
Publikováno v:
Cell Reports, Vol 9, Iss 6, Pp 2001-2010 (2014)
Genomic rearrangements are a common cause of human congenital abnormalities. However, their origin and consequences are poorly understood. We performed molecular analysis of two patients with congenital disease who carried de novo genomic rearrangeme
Externí odkaz:
https://doaj.org/article/3fde279ae3264a15b1b84b25ba00f8e2
Autor:
Sjoerd J. Klaasen, My Anh Truong, Richard H. van Jaarsveld, Isabella Koprivec, Valentina Štimac, Sippe G. de Vries, Patrik Risteski, Snježana Kodba, Kruno Vukušić, Kim L. de Luca, Joana F. Marques, Elianne M. Gerrits, Bjorn Bakker, Floris Foijer, Jop Kind, Iva M. Tolić, Susanne M. A. Lens, Geert J. P. L. Kops
Publikováno v:
Nature
Nature, 607, 604-609
Nature, 607, pp. 604-609
Nature, 607(7919), 604-609. Nature Publishing Group
Nature, 607, 604-609
Nature, 607, pp. 604-609
Nature, 607(7919), 604-609. Nature Publishing Group
Chromosome segregation errors during cell divisions generate aneuploidies and micronuclei, which can undergo extensive chromosomal rearrangements such as chromothripsis [1, 2, 3, 4, 5]. Selective pressures then shape distinct aneuploidy and rearrange
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::daaaba46aeec6daf7ebdc7fd431951dd
http://fulir.irb.hr/7580/
http://fulir.irb.hr/7580/
Autor:
Christian Valdes-Quezada, Sandra S. de Vries, Yuko Sato, Franka J. Rang, Ellen Boele, Kim L. de Luca, Jeroen Bakkers, Jop Kind, Hiroshi Kimura, Phong D. Nguyen, Isabel Guerreiro
Recent advances in single-cell sequencing technologies have enabled simultaneous measurement of multiple cellular modalities, including various combinations of transcriptome, genome and epigenome. However, comprehensive profiling of the histone post-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5507d3f7362950bbd2480e66fc71a944
https://doi.org/10.1101/2021.10.26.465688
https://doi.org/10.1101/2021.10.26.465688
Autor:
Sjoerd J, Klaasen, My Anh, Truong, Richard H, van Jaarsveld, Isabella, Koprivec, Valentina, Štimac, Sippe G, de Vries, Patrik, Risteski, Snježana, Kodba, Kruno, Vukušić, Kim L, de Luca, Joana F, Marques, Elianne M, Gerrits, Bjorn, Bakker, Floris, Foijer, Jop, Kind, Iva M, Tolić, Susanne M A, Lens, Geert J P L, Kops
Publikováno v:
Nature. 607(7919)
Chromosome segregation errors during cell divisions generate aneuploidies and micronuclei, which can undergo extensive chromosomal rearrangements such as chromothripsis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d27ceb4bd0faa144da62ebd8aa38b4b1
https://pubmed.ncbi.nlm.nih.gov/35831567
https://pubmed.ncbi.nlm.nih.gov/35831567
Autor:
Kim L, de Luca, Jop, Kind
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2157
The organization of DNA within the eukaryotic nucleus is important for cellular processes such as regulation of gene expression and repair of DNA damage. To comprehend cell-to-cell variation within a complex system, systematic analysis of individual
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4d5357f3cbb31b0274649a38027a0de1
https://pubmed.ncbi.nlm.nih.gov/32820403
https://pubmed.ncbi.nlm.nih.gov/32820403
Autor:
Jop Kind, Kim L. de Luca
Publikováno v:
Methods in Molecular Biology ISBN: 9781071606636
The organization of DNA within the eukaryotic nucleus is important for cellular processes such as regulation of gene expression and repair of DNA damage. To comprehend cell-to-cell variation within a complex system, systematic analysis of individual
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fde3287c87b017adbf531aed64f23c9a
https://doi.org/10.1007/978-1-0716-0664-3_9
https://doi.org/10.1007/978-1-0716-0664-3_9
Autor:
Siddharth S. Dey, Sandra S. de Vries, Dylan Mooijman, Kim L. de Luca, Franka J. Rang, Jop Kind, Alex Chialastri, Koos Rooijers, Silke J A Lochs, Corina M. Markodimitraki
Publikováno v:
Nat Protoc
Nature Protocols, 15(6), 1922-1953. Nature Publishing Group
Nature Protocols, 15(6), 1922-1953. Nature Publishing Group
Protein-DNA interactions are essential for establishing cell type-specific chromatin architecture and gene expression. We recently developed scDam&T-seq, a multi-omics method that can simultaneously quantify protein-DNA interactions and the transcrip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::448d28caf6d66914c2a6bf94b54d4c42
https://pubmed.ncbi.nlm.nih.gov/32350457
https://pubmed.ncbi.nlm.nih.gov/32350457