Zobrazeno 1 - 10
of 158
pro vyhledávání: '"Kim Khoo"'
Autor:
Anya C. Jones, Jonatan Leffler, Ingrid A. Laing, Joelene Bizzintino, Siew-Kim Khoo, Peter N. LeSouef, Peter D. Sly, Patrick G. Holt, Deborah H. Strickland, Anthony Bosco
Publikováno v:
Respiratory Research, Vol 24, Iss 1, Pp 1-12 (2023)
Abstract Asthma exacerbations in children are associated with respiratory viral infection and atopy, resulting in systemic immune activation and infiltration of immune cells into the airways. The gene networks driving the immune activation and subseq
Externí odkaz:
https://doaj.org/article/18ac5eb4bd4b4257b8ceb0da32978369
Autor:
Amir Ariff, Yong Song, Ruth Aguilar, Augusto Nhabomba, Maria Nelia Manaca, Siew-Kim Khoo, Selma Wiertsema, Quique Bassat, Arnoldo Barbosa, Llorenç Quintó, Ingrid A. Laing, Caterina Guinovart, Pedro L. Alonso, Carlota Dobaño, Peter Le Souëf, Guicheng Zhang
Publikováno v:
Malaria Journal, Vol 22, Iss 1, Pp 1-9 (2023)
Abstract Background Malaria is a deadly disease caused by Plasmodium spp. Several blood phenotypes have been associated with malarial resistance, which suggests a genetic component to immune protection. Methods One hundred and eighty-seven single nuc
Externí odkaz:
https://doaj.org/article/8cef9e578a3c426dbe18e719a17859cd
Publikováno v:
Endocrinology, Diabetes & Metabolism Case Reports, Vol 1, Iss 1, Pp 1-5 (2021)
Polycystic ovarian syndrome (PCOS) is associated with menstrual irregularities, ovulatory dysfunction, hirsutism, insulin resistance, obesity and metabolic syndrome but is rarely associated with severe hyperandrogenaemia and virilisation resulting in
Externí odkaz:
https://doaj.org/article/601c392ae8064c20b0b18ccdb5dde98d
Autor:
Jing Guo, Xiaoping Zhang, Aarti Saiganesh, Christopher Peacock, Emilija Filipovska-Naumovska, Shu Chen, Siew-Kim Khoo, Gary Dykes, Belinda Hales, Peter Le Souëf, Guicheng(Brad) Zhang
Publikováno v:
World Allergy Organization Journal, Vol 13, Iss 8, Pp 100164- (2020)
Externí odkaz:
https://doaj.org/article/56b4d897848e4ad8a85ca69b2d25f4a0
Publikováno v:
Journal of the ASEAN Federation of Endocrine Societies, Vol 35, Iss 1 (2020)
Thyrotoxicosis is a well-recognized cause of myopathy, but rarely presents as acute flaccid quadriparesis. We report a 25-year-old female with underlying uncontrolled Graves’ disease who presented with thyroid storm and acute flaccid quadriparesis
Externí odkaz:
https://doaj.org/article/6f2ab9725dd944c2b198e1d5b4fb39e8
Autor:
Yong Song, Michelle J. Schwager, Vibeke Backer, Jing Guo, Celeste Porsbjerg, Siew-Kim Khoo, Ingrid A. Laing, Eric K. Moses, Peter LeSouëf, Guicheng (Brad) Zhang
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Abstract The prevalence of asthma and allergic diseases is disproportionately distributed among different populations, with an increasing trend observed in Western countries. Here we investigated how the environment affected genotype-phenotype associ
Externí odkaz:
https://doaj.org/article/4df8280c1da84ecdb038918a3168727a
Autor:
Leah Cuthbertson, Stephen W C Oo, Michael J Cox, Siew-Kim Khoo, Des W Cox, Glenys Chidlow, Kimberley Franks, Franciska Prastanti, Meredith L Borland, James E Gern, David W Smith, Joelene A Bizzintino, Ingrid A Laing, Peter N Le Souëf, Miriam F Moffatt, William O C Cookson
Publikováno v:
PLoS ONE, Vol 14, Iss 10, p e0223990 (2019)
Acute viral wheeze in children is a major cause of hospitalisation and a major risk factor for the development of asthma. However, the role of the respiratory tract microbiome in the development of acute wheeze is unclear. To investigate whether seve
Externí odkaz:
https://doaj.org/article/9744bb3b496547a790bdfc405d1bc6f7
Publikováno v:
Case Reports in Cardiology, Vol 2018 (2018)
Severe thyrotoxicosis can present with a myriad of cardiovascular complications. It may be mild features such as palpitations, tachycardia, and exertional dyspnea or may progress to life-threatening consequences such as atrial fibrillation, tachyarrh
Externí odkaz:
https://doaj.org/article/c8c7a35ca3064e7d8f6d1d69396fdaaf
Autor:
Glenys Chidlow, Peter Le Souef, Joelene Bizzintino, Guicheng Zhang, Yury A. Bochkov, Kimberley Franks, Franciska Prastanti, James E. Gern, Meredith L Borland, Des W. Cox, Ingrid A. Laing, Stephen Oo, David W. Smith, Siew-Kim Khoo
Publikováno v:
Pediatric Infectious Disease Journal. 40:873-879
BACKGROUND Acute wheezing is one of the most common hospital presentations for young children. Respiratory syncytial virus (RSV) and rhinovirus (RV) species A, B and the more recently described species C are implicated in the majority of these presen
Autor:
Salome Abbott, Robin J. Green, Siew-Kim Khoo, Joelene Bizzintino, Guicheng Zhang, Peter N. Le Souëf, Andrew J. Currie, Julie Hibbert, Ingrid A. Laing, Alicia A. Annamalay
Publikováno v:
Journal of Medical Virology. 93:3647-3655
Altered host immune responses are considered to play a key role in the pathogenesis of acute lower respiratory infections (ALRI). The existing literature on cytokine responses in ALRI is largely focussed on adults from developed countries and there a