Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Kim Juhani Blomqvist"'
Autor:
Tuomas Lilius, Hanna Viisanen, Katarzyna Anna Dudek, Fredrik Harry Gustav Ahlström, Jouko Laitila, Eija Kalso, Kert Mätlik, Pekka Rauhala, Kim Juhani Blomqvist
Publikováno v:
Blomqvist, K J, Dudek, K A, Viisanen, H, Matlik, K, Ahlstrom, F H G, Laitila, J, Kalso, E A, Rauhala, P V & Lilius, T O 2022, ' Antagonism of peripheral opioid receptors by methylnaltrexone does not prevent morphine tolerance in rats ', Journal of Neuroscience Research, vol. 100, no. 1, pp. 329-338 . https://doi.org/10.1002/jnr.24638
Journal of Neuroscience Research
Journal of Neuroscience Research
Opioids are effective analgesics in the management of severe pain. However, tolerance, leading to dose escalation and adverse effects are significant limiting factors in their use. The role of peripheral opioid receptors in analgesia has been discuss
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abc143dc2a9cc9d9140206a8fec43310
https://curis.ku.dk/ws/files/289227935/Antagonism_of_peripheral_opioid.pdf
https://curis.ku.dk/ws/files/289227935/Antagonism_of_peripheral_opioid.pdf
Autor:
Tuomas Lilius, Kim Juhani Blomqvist, Pekka Rauhala, Hanna Viisanen, Fredrik Harry Gustav Ahlström, Kert Mätlik, Yulia Sidorova, Eija Kalso, X. Liu
Publikováno v:
Ahlstrom, F H G, Matlik, K, Viisanen, H, Blomqvist, K J, Liu, X, Lilius, T O, Sidorova, Y, Kalso, E A & Rauhala, P V 2021, ' Spared Nerve Injury Causes Sexually Dimorphic Mechanical Allodynia and Differential Gene Expression in Spinal Cords and Dorsal Root Ganglia in Rats ', Molecular Neurobiology, vol. 58, pp. 5396–5419 . https://doi.org/10.1007/s12035-021-02447-1
Molecular Neurobiology
Molecular Neurobiology
BACKGROUND Neuropathic pain (NP) is more prevalent in women. However, females are under-represented in animal experiments, and the mechanisms of sex differences remain inadequately understood. Using the spared nerve injury (SNI) model in rats, we cha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17884155d892aae330010fb7e2df8981
https://doi.org/10.21203/rs.3.rs-33768/v1
https://doi.org/10.21203/rs.3.rs-33768/v1
Autor:
Fredrik Harry Gustav Ahlström, Hanna Viisanen, Jouko Laitila, Kim Juhani Blomqvist, Tuomas Lilius, Pekka Rauhala, Kert Mätlik, Katarzyna Anna Dudek, Eija Kalso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c589ffe1ea4313e22c279c8717b29973
https://doi.org/10.1002/jnr.24638/v3/response1
https://doi.org/10.1002/jnr.24638/v3/response1
Autor:
Tuomas Lilius, Viljami Jokinen, Hanna Viisanen, Fredrik Harry Gustav Ahlström, Pekka Rauhala, Yulia Sidorova, Kim Juhani Blomqvist, Ilida Suleymanova, Eija Kalso
Publikováno v:
Blomqvist, K J, Viisanen, H, Ahlstrom, F H G, Jokinen, V, Sidorova, Y A, Suleymanova, I, Rauhala, P V, Kalso, E A & Lilius, T O 2020, ' Morphine-3-glucuronide causes antinociceptive cross-tolerance to morphine and increases spinal substance P expression ', European Journal of Pharmacology, vol. 875, 173021 . https://doi.org/10.1016/j.ejphar.2020.173021
European Journal of Pharmacology
European Journal of Pharmacology
Morphine-3-glucuronide (M3G), the main metabolite of morphine, has been implicated in the development of tolerance and of opioid-induced hyperalgesia, both limiting the analgesic use of morphine. We evaluated the acute and chronic effects of M3G and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::673c616608f79bac53572a6cbb3569fc
https://curis.ku.dk/ws/files/239562235/Morphine_3_glucuronide_causes_antinociceptive_cross_tolerance_to_morphine_and_increases_spinal_substance_P_expression.pdf
https://curis.ku.dk/ws/files/239562235/Morphine_3_glucuronide_causes_antinociceptive_cross_tolerance_to_morphine_and_increases_spinal_substance_P_expression.pdf