Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Kim I. Chisholm"'
Autor:
Kim I Chisholm, Mattéa J. Finelli
Publikováno v:
BMC Neuroscience, Vol 24, Iss 1, Pp 1-3 (2023)
Abstract This editorial highlights common challenges faced by early career researchers (ECRs) who play a crucial role in our research community. We propose that enhancing the experiences of ECRs will yield benefits to the entire scientific community
Externí odkaz:
https://doaj.org/article/d6b3bbe8b40c4104b8312dfe71b27131
Heightened spontaneous activity in sensory neurons is often reported in individuals living with chronic pain. It is possible to study this activity in rodents using electrophysiology, but these experiments require great skill and can be prone to bias
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::233c8b4c869cfc5306a41f6781ce742a
https://doi.org/10.1101/2023.01.12.523728
https://doi.org/10.1101/2023.01.12.523728
Satellite glial cells (SGCs) are important for proper neuronal function of primary sensory neurons to whom they provide homeostatic support. Most research of SGC function has been performed within vitrostudies, but recent advances inin vivocalcium im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28d0c963ce6a670fe3548c62270db96b
https://doi.org/10.1101/2022.10.07.511264
https://doi.org/10.1101/2022.10.07.511264
Autor:
Teodora Trendafilova, Kaustubh Adhikari, Annina B. Schmid, Ryan Patel, Erika Polgár, Kim I. Chisholm, Steven J. Middleton, Kieran Boyle, Allen C. Dickie, Evangelia Semizoglou, Jimena Perez-Sanchez, Andrew M. Bell, Luis Miguel Ramirez-Aristeguieta, Samar Khoury, Aleksandar Ivanov, Hendrik Wildner, Eleanor Ferris, Juan-Camilo Chacón-Duque, Sophie Sokolow, Mohamed A. Saad Boghdady, André Herchuelz, Pierre Faux, Giovanni Poletti, Carla Gallo, Francisco Rothhammer, Gabriel Bedoya, Hanns Ulrich Zeilhofer, Luda Diatchenko, Stephen B. McMahon, Andrew J. Todd, Anthony H. Dickenson, Andres Ruiz-Linares, David L. Bennett
Publikováno v:
Neuron, 110 (16)
Repeated application of noxious stimuli leads to a progressively increased pain perception; this temporal summation is enhanced in and predictive of clinical pain disorders. Its electrophysiological correlate is “wind-up,” in which dorsal horn sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3df091f7ef0a309761bab165ab5c500b
https://hdl.handle.net/20.500.11850/566573
https://hdl.handle.net/20.500.11850/566573
Autor:
Kim I. Chisholm, Stephen B. McMahon, Andrew J. Todd, Laure Lo Re, Maria Gutierrez-Mecinas, Erika Polgár
Publikováno v:
Pain
Supplemental Digital Content is Available in the Text. We here report on the use of in vivo optical imaging to study lamina I projection neurons and their response to cutaneous stimuli.
Lamina I of the dorsal horn, together with its main output
Lamina I of the dorsal horn, together with its main output
Autor:
Kim I. Chisholm, Martyn G Jones, Joseph O Lloyd, Giorgio Lambru, Adnan Al-Kaisy, Beatrice Oehle, Bright N Okine, Anna P. Andreou, Stephen B. McMahon
Publikováno v:
Neurotherapeutics
Single-pulse transcranial magnetic stimulation (sTMS) of the occipital cortex is an effective migraine treatment. However, its mechanism of action and cortical effects of sTMS in migraine are yet to be elucidated. Using calcium imaging and GCaMP-expr
Autor:
Kim I. Chisholm, Stephen B. McMahon
Publikováno v:
Neuromethods ISBN: 9781071620380
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f757a5f038167bb8a46732110aa4fa96
https://doi.org/10.1007/978-1-0716-2039-7_14
https://doi.org/10.1007/978-1-0716-2039-7_14
Autor:
Kirsty Bannister, Mateusz Kucharczyk, Anthony H. Dickenson, Stephen B. McMahon, Franziska Denk, Kim I. Chisholm
Publikováno v:
Pain
Kucharczyk, M, Chisholm, K, Denk, F, Dickenson, A, Bannister, K & McMahon, S 2020, ' The impact of bone cancer on the peripheral encoding of mechanical pressure stimuli ', Pain, vol. 161, no. 8, pp. 1894-1905 . https://doi.org/10.1097/j.pain.0000000000001880
Kucharczyk, M, Chisholm, K, Denk, F, Dickenson, A, Bannister, K & McMahon, S 2020, ' The impact of bone cancer on the peripheral encoding of mechanical pressure stimuli ', Pain, vol. 161, no. 8, pp. 1894-1905 . https://doi.org/10.1097/j.pain.0000000000001880
Supplemental Digital Content is Available in the Text. In vivo GCaMP6s imaging of hind-limb sensory neurons revealed that the number of mechanically responsive sensory neurons triples in bone cancer conditions.
Skeletal metastases are frequently
Skeletal metastases are frequently
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::243cb444e7772ed7d0efa35a0dbf8dd1
Autor:
Douglas M, Lopes, Franziska, Denk, Kim I, Chisholm, Tesha, Suddason, Camille, Durrieux, Matthew, Thakur, Clive, Gentry, Stephen B, McMahon
Publikováno v:
Pain
Supplemental Digital Content is Available in the Text. Mast cells do not play a role as a direct nociceptor sensitiser during acute inflammatory pain and in mechanical hypersensitivity triggered by local nerve growth factor.
The immune and senso
The immune and senso
Publikováno v:
eNeuro
Greater emphasis on the study of intact cellular networks in their physiological environment has led to rapid advances in intravital imaging of the central nervous system (CNS), while the peripheral system remains largely unexplored. To assess large