Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Kim Holmstrom"'
Autor:
Boye Schnack Nielsen, Natasha H. Madsen, Jesper Larsen, Hjalte M. Larsen, Monika Gad, Kim Holmstrom
Publikováno v:
Cancer Research. 83:4566-4566
3D cancer cell cultures have enabled new opportunities for replacing compound testing in experimental animals and provide a basis for high content work-flows for drug testing. Here we present data obtained from 3D multicellular tumor spheroids (MCTS)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3bbf13d26e727654d0738c04c529a3c8
https://doi.org/10.1158/1538-7445.am2023-4566
https://doi.org/10.1158/1538-7445.am2023-4566
Autor:
Boye Schnack Nielsen, Natasha Helleberg Madsen, Jesper Larsen, Isabella Skandorff, Monika Gad, Kim Holmstrøm
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
3D cancer cell cultures have enabled new opportunities for replacing compound testing in experimental animals. However, most solid tumors are composed of multiple cell types, including fibroblasts. In this study we developed multicellular tumor heter
Externí odkaz:
https://doaj.org/article/ed34f1c7b90146b7bb62572bf29dc2c3
Autor:
Jaslin Pallikkunnath James, Boye Schnack Nielsen, Ib Jarle Christensen, Ebbe Langholz, Mikkel Malham, Tim Svenstrup Poulsen, Kim Holmstrøm, Lene Buhl Riis, Estrid Høgdall
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Differential diagnosis of inflammatory bowel disease (IBD) to Crohn’s disease (CD) or ulcerative colitis (UC) is crucial for treatment decision making. With the aim of generating a clinically applicable molecular-based tool to classify IBD
Externí odkaz:
https://doaj.org/article/d978c2381668411fa9631bc9104e9339
Autor:
Christopher J. Barnes, Maria Asplund, Maja-Lisa Clausen, Linett Rasmussen, Caroline Meyer Olesen, Yasemin Topal Yüksel, Paal Skytt Andersen, Thomas Litman, Kim Holmstrøm, Lene Bay, Blaine Gabriel Fritz, Thomas Bjarnsholt, Tove Agner, Anders Johannes Hansen
Publikováno v:
BMC Microbiology, Vol 23, Iss 1, Pp 1-12 (2023)
Abstract There has been considerable research into the understanding of the healthy skin microbiome. Similarly, there is also a considerable body of research into whether specific microbes contribute to skin disorders, with atopic dermatitis (AD) rou
Externí odkaz:
https://doaj.org/article/0a8ec7e8ca4f4a558e5a445308b7fd0c
Autor:
Troels Ronco, Line H. Kappel, Maria F. Aragao, Niccolo Biagi, Søren Svenningsen, Jørn B. Christensen, Anders Permin, Lasse Saaby, Kim Holmstrøm, Janne K. Klitgaard, Artur J. Sabat, Viktoria Akkerboom, Monica Monaco, Marco Tinelli, Alexander W. Friedrich, Bimal Jana, Rikke H. Olsen
Publikováno v:
Frontiers in Microbiology, Vol 12 (2022)
Multidrug-resistant pathogens constitute a serious global issue and, therefore, novel antimicrobials with new modes of action are urgently needed. Here, we investigated the effect of a phenothiazine derivative (JBC 1847) with high antimicrobial activ
Externí odkaz:
https://doaj.org/article/a70ca383e2d94fc0aec69fc9b38b1f43
Autor:
Silvia Aldi, Ljubica Perisic Matic, Gregory Hamm, Daniëlle van Keulen, Dennie Tempel, Kim Holmstrøm, Agnieszka Szwajda, Boye Schnack Nielsen, Valur Emilsson, Rima Ait-Belkacem, Mariette Lengquist, Gabrielle Paulsson-Berne, Per Eriksson, Jan H.N. Lindeman, Alain J. Gool, Jonathan Stauber, Ulf Hedin, Eva Hurt-Camejo
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 10, Iss , Pp 17-28 (2018)
Variants in the PLPP3 gene encoding for lipid phosphate phosphohydrolase 3 have been associated with susceptibility to atherosclerosis independently of classical risk factors. PLPP3 inactivates lysophosphatidic acid (LPA), a pro-inflammatory, pro-thr
Externí odkaz:
https://doaj.org/article/7bfc8ac6211a4952996ab2d554be695f
Autor:
Danielle van Keulen, Marianne G Pouwer, Valur Emilsson, Ljubica Perisic Matic, Elsbet J Pieterman, Ulf Hedin, Vilmundur Gudnason, Lori L Jennings, Kim Holmstrøm, Boye Schnack Nielsen, Gerard Pasterkamp, Jan H N Lindeman, Alain J van Gool, Maarten D Sollewijn Gelpke, Hans M G Princen, Dennie Tempel
Publikováno v:
PLoS ONE, Vol 14, Iss 8, p e0221477 (2019)
ObjectivePrevious studies indicate a role for Oncostatin M (OSM) in atherosclerosis and other chronic inflammatory diseases for which inhibitory antibodies are in development. However, to date no intervention studies with OSM have been performed, and
Externí odkaz:
https://doaj.org/article/ca346d3188e04a0dac053e012ce18eb6
Autor:
Trine Møller, Jaslin P James, Kim Holmstrøm, Flemming B Sørensen, Jan Lindebjerg, Boye S Nielsen
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 8, p 1907 (2019)
MicroRNA-21 (miR-21) is upregulated in many cancers including colon cancers and is a prognostic indicator of recurrence and poor prognosis. In colon cancers, miR-21 is highly expressed in stromal fibroblastic cells and more weakly in a subset of canc
Externí odkaz:
https://doaj.org/article/97dec9bcd9ce4a47ba342d3fecd6b251