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pro vyhledávání: '"Kim H. Hee"'
Autor:
Vincent H. Tam, Lawrence S. Lee, Tat-Ming Ng, Tze-Peng Lim, Benjamin P. Z. Cherng, Hafeez Adewusi, Kim H. Hee, Ying Ding, Shimin Jasmine Chung, Li-Min Ling, Piotr Chlebicki, Andrea L. H. Kwa, David C. Lye
Publikováno v:
Microorganisms, Vol 8, Iss 11, p 1814 (2020)
Polymyxin B is the last line of defense in treating multidrug-resistant gram-negative bacterial infections. Dosing of polymyxin B is currently based on total body weight, and a substantial intersubject variability has been reported. We evaluated the
Externí odkaz:
https://doaj.org/article/b66fe64fb08b464e813d9030607014ff
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 102
Rifampicin (RIF) and isoniazid (INH), first line drugs for the treatment of tuberculosis, are known to cause hepatotoxicity as a serious adverse side effect. To further understand the pharmacokinetic parameters of these two drugs, we have developed a