Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Kim H. Brown"'
Autor:
J. Kimble Frazer, Lance A. Batchelor, Diana F. Bradley, Kim H. Brown, Kimberly P. Dobrinski, Charles Lee, Nikolaus S. Trede
Publikováno v:
Advances in Hematology, Vol 2012 (2012)
Genomic instability plays a crucial role in oncogenesis. Somatically acquired mutations can disable some genes and inappropriately activate others. In addition, chromosomal rearrangements can amplify, delete, or even fuse genes, altering their functi
Externí odkaz:
https://doaj.org/article/785154bf8e2b4e0782fa45d7a00fe098
Autor:
Eleanor Y Chen, Kimberly P Dobrinski, Kim H Brown, Ryan Clagg, Elena Edelman, Myron S Ignatius, Jin Yun Helen Chen, Jillian Brockmann, G Petur Nielsen, Sridhar Ramaswamy, Charles Keller, Charles Lee, David M Langenau
Publikováno v:
PLoS Genetics, Vol 9, Iss 8, p e1003727 (2013)
Human cancer genomes are highly complex, making it challenging to identify specific drivers of cancer growth, progression, and tumor maintenance. To bypass this obstacle, we have applied array comparative genomic hybridization (array CGH) to zebrafis
Externí odkaz:
https://doaj.org/article/bdb040027d8c49349d04d4103bc0795b
Autor:
Kim H. Brown, Joshua J. Faber-Hammond
Publikováno v:
Human Genetics. 135:727-740
The human genome reference (HGR) completion marked the genomics era beginning, yet despite its utility universal application is limited by the small number of individuals used in its development. This is highlighted by the presence of high-quality se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e0a7e7c9a277c328a445a706322fd28
https://doi.org/10.1007/s00439-016-1667-5
https://doi.org/10.1007/s00439-016-1667-5
Publikováno v:
Zebrafish. 16(1)
Zebrafish (Danio rerio) are a widely utilized model system for human disorders, but common laboratory strains have distinct behavioral and physiological differences. Accompanying these known strain differences, commonly used “wildtype” zebrafish
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab5c785f2232390667256b1cba921491
https://pubmed.ncbi.nlm.nih.gov/30418105
https://pubmed.ncbi.nlm.nih.gov/30418105
Autor:
Jarkko Salojärvi, Lindsay A. Holden, Kim H. Brown, Hannes Lohi, Meharji Arumilli, Marjo K. Hytönen, Sruthi Hundi
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Dogs are excellent animal models for human disease. They have extensive veterinary histories, pedigrees, and a unique genetic system due to breeding practices. Despite these advantages, one factor limiting their usefulness is the canine genome refere
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e988ac749fc669fd9ab63c14a5f1e6d
http://europepmc.org/articles/PMC6052005
http://europepmc.org/articles/PMC6052005
Autor:
Kim H. Brown, C. C. Yildirimer
Publikováno v:
Journal of applied microbiology.
AIMS This study focused on intestinal microbiome variation across the phylogeogrpahic divide of rainbow trout and its potential functional effects on ocean migration. METHODS AND RESULTS Hindgut intestinal contents were analysed using the 16S V4 hype
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02d509f37bc99a04d498a1fa0e2c80d1
https://pubmed.ncbi.nlm.nih.gov/30074661
https://pubmed.ncbi.nlm.nih.gov/30074661
Autor:
Lindsay A. Holden, Kim H. Brown
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Common strains of wildtype zebrafish (Danio rerio) have unique genomic features including SNPs and CNV, but strain information often goes unreported in the literature. As a result, the confounding effects of interstrain variation makes repetition of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6760d5f499f3b8d853af7b489ef11d0c
http://europepmc.org/articles/PMC5859126
http://europepmc.org/articles/PMC5859126
Publikováno v:
Genome Biology and Evolution
Salmonids present an excellent model for studying evolution of young sex-chromosomes. Within the genus, Oncorhynchus, at least six independent sex-chromosome pairs have evolved, many unique to individual species. This variation results from the movem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1b19d057000a247ab6ea06e7d02f72e
https://doi.org/10.1093/gbe/evv123
https://doi.org/10.1093/gbe/evv123
Autor:
Joshua J. Faber-Hammond, Kim H. Brown
Zebrafish represents the third vertebrate with an officially completed genome, yet it remains incomplete with additions and corrections continuing with the current release, GRCz10, having 13% of zebrafish cDNA sequences unmapped. This disparity may r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd1e2e08cdda1b038f90dcd70cf0951d
https://europepmc.org/articles/PMC4799696/
https://europepmc.org/articles/PMC4799696/
Autor:
Charles Lee, Nikolaus S. Trede, Diana F. Bradley, Kimberly P. Dobrinski, J. Kimble Frazer, Kim H. Brown, Lance Batchelor
Publikováno v:
Advances in Hematology, Vol 2012 (2012)
Advances in Hematology
Advances in Hematology
Genomic instability plays a crucial role in oncogenesis. Somatically acquired mutations can disable some genes and inappropriately activate others. In addition, chromosomal rearrangements can amplify, delete, or even fuse genes, altering their functi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ba561e2bf168044353277e5dfa266dc
https://doi.org/10.1155/2012/627920
https://doi.org/10.1155/2012/627920