Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Kim Goldenstein"'
Autor:
Andreas Michalsen, Kim Goldenstein, Peter Kardos, Ludger Klimek, Jürgen Palm, Dajana Parganlija, Johannes Stöckl
Publikováno v:
PLoS ONE, Vol 19, Iss 1 (2024)
Externí odkaz:
https://doaj.org/article/249d61ea611345dfb966d47eb87609e2
Publikováno v:
Drug Discovery Today. 24:560-566
Nonalcoholic steatohepatitis (NASH) is emerging as a major public health issue for the 21st century and is associated with significant liver-related morbidity and mortality. At present, there are no approved drug therapies for NASH. Consequently, NAS
Publikováno v:
Angewandte Chemie. 113:591-594
Publikováno v:
Tetrahedron. 56:4173-4185
Several enantiopure spiroisoxazoline amides were prepared from tert-butylester 22, which is obtained via an enantiotopic groups differentiating high pressure Diels–Alder cycloaddition. Treatment of these amides with an isoxazoline-splitting enzyme,
Publikováno v:
ChemInform. 32
Publikováno v:
Angewandte Chemie (International ed. in English). 40(3)
Publikováno v:
ChemInform. 31
Several enantiopure spiroisoxazoline amides were prepared from tert-butylester 22, which is obtained via an enantiotopic groups differentiating high pressure Diels–Alder cycloaddition. Treatment of these amides with an isoxazoline-splitting enzyme,
Publikováno v:
Angewandte Chemie (International ed. in English). 40(3)
Six at a time! Up to six stereogenic centers can be diastereoselectively formed in one step in three-component domino reactions of 4-silyloxypyrylium triflates with 2-silyloxybuta-1,3-dienes. Annulated or bridged ring systems such as 1 and 2, respect