Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Kim F. Albizati"'
Autor:
Angela Birchler, Aubrey A. Haddach, Dale L. Rieger, Bennett C. Borer, Barbara C. M. Potts, Michelle Fugett, Alan W. Grubbs, Miguel Pagan, Juliette K Busse, Travis Remarchuk, Srinivasan Babu, Szendroi Robert J, Kim F. Albizati, Rick Rodriguez, Tony Tibbetts, Whitten Kathleen R, Jim Shanley
Publikováno v:
Tetrahedron Letters. 42:6481-6485
This letter describes a new synthesis of the HIV-protease inhibitor nelfinavir. The synthesis features a selective opening of a d -tartaric acid-derived cyclic sulfate with nitrogen nucleophiles.
Publikováno v:
Magnetic Resonance in Chemistry. 37:393-400
Liquid chromatography (LC)–NMR spectroscopy was used to obtain detailed information regarding the structure of a bulk drug impurity present in glycinamide ribonucleotide transformylase (GART) inhibitor AG2034. The LC–NMR experiments (1D 1H and 2D
Publikováno v:
Organic Preparations and Procedures International. 26:1-84
Autor:
Kim F. Albizati, V. Vaillancourt
Publikováno v:
Journal of the American Chemical Society. 115:3499-3502
The versatility of brominated camphor derivatives as six-membered-ring chiral building blocks in the synthesis of compounds of mixed biogenesis has been demonstrated in an eight-step synthesis of (+)-hapalindole Q from (+)- (1R)-9-bromocamphor in an
Autor:
Kim F. Albizati, Yun Bo Zhao
Publikováno v:
Tetrahedron Letters. 34:575-578
Stereocontrol in the carbonyl reductions of the titled leads compounds leads to a variety of hydroxylated spiroketals. Reductive cleavage leads to tetrahydropyrans with complete stereocontrol over 7 stereogenic centers.
Publikováno v:
ChemInform. 22
An efficient synthesis of α-(hydroxymethyl) ketones from β-keto esters has been developed, which is experimentally simple, amenable to large scale production and provides products of high purity without resort to chromatography in most cases. The m
Autor:
Kim F. Albizati, D. J. Faulkner, V. Vaillancourt, Olivier Richou, Mohamad R. Agharahimi, Uma N. Sundram
Publikováno v:
ChemInform. 22
Publikováno v:
ChemInform. 22
Autor:
Desmond H. Murray, Kim F. Albizati
Publikováno v:
ChemInform. 22
Trialkylsilyloxyallyl cations 2 with a π-donating methoxy substituent at the allylic termini are generated from nonhalogenated substrates via treatment of 5b-e with Lewis acids. 2 undergoes stereo- and regioselective cycloaddition with furans yieldi
Publikováno v:
ChemInform. 23