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pro vyhledávání: '"Kim Ellen Schmidt"'
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Frontiers in Immunology
Frontiers in Immunology
Ever since the development of the first vaccine more than 200 years ago, vaccinations have greatly decreased the burden of infectious diseases worldwide, famously leading to the eradication of small pox and allowing the restriction of diseases such a
Autor:
Johannes Lutz, Mohamed Habbeddine, Michael J. Hope, Barbara L. Mui, Ying K. Tam, Mariola Fotin-Mleczek, Thomas D. Madden, Sandra Lazzaro, Kim Ellen Schmidt, Patrick Baumhof, Regina Heidenreich
Publikováno v:
NPJ Vaccines
npj Vaccines, Vol 2, Iss 1, Pp 1-9 (2017)
npj Vaccines, Vol 2, Iss 1, Pp 1-9 (2017)
mRNA represents a promising new vaccine technology platform with high flexibility in regard to development and production. Here, we demonstrate that vaccines based on sequence optimized, chemically unmodified mRNA formulated in optimized lipid nanopa