Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Kim Douma"'
Publikováno v:
International Journal of Audiology, 56(3), 174-185. Routledge/Taylor & Francis Group
Objective: This study investigated the hypotheses that (1) prelingually deafened CI users do not have perfect electrode discrimination ability and (2) the deactivation of non-discriminable electrodes can improve auditory performance. Design: Electrod
Autor:
Niko Deckers, Felix M. Mottaghy, Dennis H. M. Kusters, Geert Hendrikx, Jan Bucerius, P. Granton, Kim Douma, Chris P. M. Reutelingsperger, Matthias Bauwens, M. De Saint-Hubert, M. Drummen
Publikováno v:
Molecular Imaging and Biology, 16(2), 246-254. Springer
PURPOSE: The purpose of this paper is to study molecular imaging of apoptosis and necrosis, two key players in atherosclerosis instability, using a multimodal imaging approach combining single photon emission computed tomography (SPECT), positron emi
Autor:
Allard Wagenaar, Tilman H. Hackeng, M. A. M. J. van Zandvoort, Mark J. Post, M. Wolters, ME Marianne Eline Kooi, Walter H. Backes, Kim Douma, R. H. M. van Hoof
Publikováno v:
Journal of Thrombosis and Haemostasis. 11:1766-1769
Autor:
Mat J.A.P. Daemen, Judith C. Sluimer, Mark J. Post, Tilman M. Hackeng, Kim Douma, Marc A. M. J. van Zandvoort, Sylvia Heeneman, Erik A.L. Biessen, Timo Rademakers
Publikováno v:
Arteriosclerosis, thrombosis, and vascular biology, 33(2), 249-256. Lippincott Williams and Wilkins
Arteriosclerosis Thrombosis and Vascular Biology, 33(2), 249-+. LIPPINCOTT WILLIAMS & WILKINS
Arteriosclerosis Thrombosis and Vascular Biology, 33(2), 249-+. LIPPINCOTT WILLIAMS & WILKINS
Objective— Neovascularization of human atherosclerotic plaques is implicated in plaque progression and destabilization, although its functional implications are yet unresolved. Here, we aimed to elucidate functional and morphological properties of
Autor:
Will A. Coumans, Wino Wijnen, Marc A. M. J. van Zandvoort, Nicole Hoebers, Michaela Diamant, Peter J. Simons, Sabrina Greulich, Jan F. C. Glatz, Kim Douma, Laura K.M. Steinbusch, Yeliz Angin, Joost J. F. P. Luiken, D. Margriet Ouwens
Publikováno v:
Biochemical Journal, 448, 43-53. Portland Press Ltd.
Angin, Y, Steinbusch, L K M, Simons, P J, Greulich, S, Hoebers, N T H, Douma, K, van Zandvoort, M A M J, Coumans, W A, Wijnen, W, Diamant, M, Ouwens, D M, Glatz, J F C & Luiken, J J F P 2012, ' CD36 inhibition prevents lipid accumulation and contractile dysfunction in rat cardiomyocytes ', Biochemical Journal, vol. 448, pp. 43-53 . https://doi.org/10.1042/BJ20120060
Angin, Y, Steinbusch, L K M, Simons, P J, Greulich, S, Hoebers, N T H, Douma, K, van Zandvoort, M A M J, Coumans, W A, Wijnen, W, Diamant, M, Ouwens, D M, Glatz, J F C & Luiken, J J F P 2012, ' CD36 inhibition prevents lipid accumulation and contractile dysfunction in rat cardiomyocytes ', Biochemical Journal, vol. 448, pp. 43-53 . https://doi.org/10.1042/BJ20120060
An increased cardiac fatty acid supply and increased sarcolemmal presence of the long-chain fatty acid transporter CD36 are associated with and contribute to impaired cardiac insulin sensitivity and function. In the present study we aimed at preventi
Optical molecular imaging of atherosclerosis using nanoparticles: shedding new light on the darkness
Publikováno v:
Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology, 3(4), 376-388. John Wiley & Sons Inc.
The application of optical nanoparticles in cardiovascular research is increasing because of the high spatiotemporal resolution and high sensitivity of optical techniques as compared with other imaging platforms. The major cause of cardiovascular eve
Autor:
Kim Douma, Walter H. Backes, Tilman M. Hackeng, Marc A. M. J. van Zandvoort, Marlies Oostendorp, Mark J. Post
Publikováno v:
Magnetic Resonance in Medicine, 64(1), 291-298. Wiley
Quantum dots labeled with paramagnetic gadolinium chelates can be applied as contrast agent for preclinical molecular MRI combined with fluorescence microscopy. Besides increasing the longitudinal relaxation rate, gadolinium-labeled quantum dots may
Autor:
Marlies Oostendorp, Mark J. Post, Tilman M. Hackeng, Marc A. M. J. van Zandvoort, Kim Douma, Walter H. Backes
Publikováno v:
Contrast Media & Molecular Imaging, 5(1), 9-17. Wiley Hindawi Partnership
Molecular magnetic resonance imaging (MRI) is increasingly used to investigate tumor angiogenic activity non-invasively. However, the pharmacokinetic behavior and tumor penetration of the often large contrast agent particles is thus far unknown. Here
Autor:
Dick W. Slaaf, Mark J. Post, Erik A.L. Biessen, Marc A. M. J. van Zandvoort, Lenneke Prinzen, Chris P. M. Reutelingsperger, Tilman M. Hackeng, Kim Douma
Publikováno v:
Small. 5:544-557
Molecular imaging contributes to future personalized medicine dedicated to the treatment of cardiovascular disease, the leading cause of mortality in industrialized countries. Endoscope-compatible optical imaging techniques would offer a stand-alone
Autor:
Roland K. Chiu, Kim Douma, Silvia Pastorekova, Marc A. M. J. van Zandvoort, Bradly G. Wouters, Ludwig Dubois, Philippe Lambin, Andrea Scozzafava, Claudiu T. Supuran
Publikováno v:
Radiotherapy and Oncology. 83:367-373
Background and purpose Carbonic anhydrase (CA) IX expression is increased in response to hypoxia. Recently, sulfonamide based carbonic anhydrase inhibitors (CAI) showing specificity for CA IX have been designed. Aim was to investigate the CAI binding